A comprehensive review of interventions in the NOD mouse and implications for translation.
暂无分享,去创建一个
R. Kahn | J. Bluestone | D. Mathis | M. Atkinson | S. Ramanujan | G. Eisenbarth | A. Rossini | C. Whiting | L. Shoda | D. L. Young | Scott E. Campbell | H. Kreuwel
[1] Michel Goldman,et al. Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. , 2005, The New England journal of medicine.
[2] D. Harlan,et al. A Single Course of Anti-CD3 Monoclonal Antibody hOKT3γ1(Ala-Ala) Results in Improvement in C-Peptide Responses and Clinical Parameters for at Least 2 Years after Onset of Type 1 Diabetes , 2005, Diabetes.
[3] J. Krischer,et al. Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1. , 2005, Diabetes care.
[4] M. Atkinson,et al. Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetes , 2004, Nature Reviews Immunology.
[5] P. Pozzilli,et al. Cytokine profile and insulin antibody IgG subclasses in patients with recent onset Type 1 diabetes treated with oral insulin , 2004, Diabetologia.
[6] E. Bonifacio,et al. Pancreatic β-Cell Function and Immune Responses to Insulin After Administration of Intranasal Insulin to Humans At Risk for Type 1 Diabetes , 2004 .
[7] Q. Mi,et al. Perturbed Homeostasis of Peripheral T Cells Elicits Decreased Susceptibility to Anti-CD3-Induced Apoptosis in Prediabetic Nonobese Diabetic Mice1 , 2004, The Journal of Immunology.
[8] G. Szot,et al. Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells. , 2004, The Journal of clinical investigation.
[9] Linrong Lu,et al. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[10] Jeffrey A. Bluestone,et al. In Vitro–expanded Antigen-specific Regulatory T Cells Suppress Autoimmune Diabetes , 2004, The Journal of experimental medicine.
[11] R. Hetzer,et al. ROLE OF THE THYMUS IN TRANSPLANTATION TOLERANCE IN MINIATURE SWINE: IV. THE THYMUS IS REQUIRED DURING THE INDUCTION PHASE, BUT NOT THE MAINTENANCE PHASE, OF RENAL ALLOGRAFT TOLERANCE1 , 2004, Transplantation.
[12] C. Hughes,et al. Of Mice and Not Men: Differences between Mouse and Human Immunology , 2004, The Journal of Immunology.
[13] M. Fujimiya,et al. Extrapancreatic insulin-producing cells in multiple organs in diabetes. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[14] J. Bluestone,et al. Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells 1 , 2003, The Journal of Immunology.
[15] T. Flotte,et al. Systemic Overexpression of IL-10 Induces CD4+CD25+ Cell Populations In Vivo and Ameliorates Type 1 Diabetes in Nonobese Diabetic Mice in a Dose-Dependent Fashion 1 , 2003, The Journal of Immunology.
[16] J. Bluestone,et al. TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes , 2003, Nature Medicine.
[17] S. Khoury,et al. The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice , 2003, The Journal of experimental medicine.
[18] J. Lohr,et al. The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens , 2003, Nature Immunology.
[19] A. Cooke,et al. Schistosoma mansoni antigens modulate the activity of the innate immune response and prevent onset of type 1 diabetes , 2003, European journal of immunology.
[20] H. Mcdevitt,et al. Tumor necrosis factor-α regulation of CD4+C25+ T cell levels in NOD mice , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[21] R. Wu,et al. The anti-inflammatory compound lisofylline prevents Type I diabetes in non-obese diabetic mice , 2002, Diabetologia.
[22] Meng Chen,et al. Suppression of Autoimmune Diabetes by Viral IL-10 Gene Transfer1 , 2002, The Journal of Immunology.
[23] P. Mottram,et al. Remission and pancreas isograft survival in recent onset diabetic NOD mice after treatment with low-dose anti-CD3 monoclonal antibodies. , 2002, Transplant immunology.
[24] D. Harlan,et al. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. , 2002, The New England journal of medicine.
[25] D. Scott,et al. Gene Transfer of Ig-Fusion Proteins Into B Cells Prevents and Treats Autoimmune Diseases1 , 2002, The Journal of Immunology.
[26] T. Flotte,et al. Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[27] Stephen S. Wilson,et al. Therapeutic Alteration of Insulin-Dependent Diabetes Mellitus Progression by T Cell Tolerance to Glutamic Acid Decarboxylase 65 Peptides In Vitro and In Vivo1 , 2001, The Journal of Immunology.
[28] H. Weiner,et al. Mucosal administration of IL-10 enhances oral tolerance in autoimmune encephalomyelitis and diabetes. , 2001, International immunology.
[29] W. Cefalu,et al. Efficacy of inhaled human insulin in type 1 diabetes mellitus: a randomised proof-of-concept study , 2001, The Lancet.
[30] A. Isacchi,et al. Early Th1 Response in Unprimed Nonobese Diabetic Mice to the Tyrosine Phosphatase-Like Insulinoma-Associated Protein 2, an Autoantigen in Type 1 Diabetes , 2000, The Journal of Immunology.
[31] E. Niki,et al. Prevention of Type I Diabetes by Low-Dose Gamma Irradiation in NOD Mice , 2000, Radiation research.
[32] M. Kasuga,et al. Suppression and acceleration of autoimmune diabetes by neutralization of endogenous interleukin-12 in NOD mice. , 2000, Diabetes.
[33] M. Cameron,et al. Immunotherapy of spontaneous type 1 diabetes in nonobese diabetic mice by systemic interleukin-4 treatment employing adenovirus vector-mediated gene transfer , 2000, Gene Therapy.
[34] C. Boitard,et al. Oral insulin administration and residual (β-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial , 2000, The Lancet.
[35] A. T. N. Group,et al. No effect of oral insulin on residual beta-cell function in recent-onset Type I diabetes (the IMDIAB VII) , 2000, Diabetologia.
[36] J. Bluestone,et al. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. , 2000, Immunity.
[37] K. Haskins,et al. Induction of Diabetes in Nonobese Diabetic Mice by Th2 T Cell Clones from a TCR Transgenic Mouse1 , 2000, The Journal of Immunology.
[38] A. Rosenbloom. Prevention of Type 1 Diabetes: Perspectives , 2000 .
[39] J. Krischer,et al. Therapeutic controversy: prevention and treatment of diabetes in children. , 2000 .
[40] F. Nicoletti,et al. Early prophylaxis with recombinant human interleukin-11 prevents spontaneous diabetes in NOD mice. , 1999, Diabetes.
[41] G. Prud’homme,et al. Intramuscular administration of expression plasmids encoding interferon‐γ receptor/IgG1 or IL‐4/IgG1 chimeric proteins protects from autoimmunity , 1999, The journal of gene medicine.
[42] I Mahmood,et al. Allometric issues in drug development. , 1999, Journal of pharmaceutical sciences.
[43] J. Petersen,et al. Insulin in oral immune "tolerance": a one-amino acid change in the B chain makes the difference. , 1999, Journal of immunology.
[44] S. W. Kim,et al. Anti-GAD Monoclonal Antibody Delays the Onset of Diabetes Mellitus in NOD Mice , 1999, Pharmaceutical Research.
[45] Meroni,et al. Endogenous interleukin‐12 only plays a key pathogenetic role in non‐obese diabetic mouse diabetes during the very early stages of the disease , 1999, Immunology.
[46] Onji,et al. Transfer of dendritic cells (DC) ex vivo stimulated with interferon‐gamma (IFN‐γ) down‐modulates autoimmune diabetes in non‐obese diabetic (NOD) mice , 1999, Clinical and experimental immunology.
[47] J. Miyazaki,et al. Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice. , 1998, Human gene therapy.
[48] K. Buschard,et al. Effect of intrathymic administration of mycobacterial heat shock protein 65 and peptide p277 on the development of diabetes in NOD mice: caution required in vaccination studies , 1998, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[49] M. Kasuga,et al. Administration of IL-4 prevents autoimmune diabetes but enhances pancreatic insulitis in NOD mice. , 1998, Clinical immunology and immunopathology.
[50] M. Atkinson,et al. Retardation or Acceleration of Diabetes in NOD/Lt Mice Mediated by Intrathymic Administration of Candidate β-Cell Antigens , 1997, Diabetes.
[51] Bhagirath Singh,et al. The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. , 1997, Immunity.
[52] R. Tisch,et al. CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice. , 1997, Journal of immunology.
[53] D. Cohen,et al. Metabolically inactive insulin analog prevents type I diabetes in prediabetic NOD mice. , 1997, The Journal of clinical investigation.
[54] L. Adorini,et al. Deviation of pancreas‐infiltrating cells to Th2 by interleukin‐12 antagonist administration inhibits autoimmune diabetes , 1997, European journal of immunology.
[55] Y. W. Kim,et al. Inhibition of diabetes in non-obese diabetic mice by nicotinamide treatment for 5 weeks at the early age. , 1997, Journal of Korean medical science.
[56] T. Maki,et al. Regulation of autoimmune diabetes by interleukin 3-dependent bone marrow-derived cells in NOD mice. , 1997, Journal of autoimmunity.
[57] M. Kurrer,et al. T Helper 2 (Th2) T Cells Induce Acute Pancreatitis and Diabetes in Immune-compromised Nonobese Diabetic (NOD) Mice , 1997, The Journal of experimental medicine.
[58] C. Peterson,et al. Dapsone Decreases the Cumulative Incidence of Diabetes in Non-Obese Diabetic Female Mice , 1997, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[59] H. Kolb,et al. Oral insulin for diabetes prevention in NOD mice: potentiation by enhancing Th2 cytokine expression in the gut through bacterial adjuvant , 1997, Diabetologia.
[60] P. Nickerson,et al. A noncytolytic IL-10/Fc fusion protein prevents diabetes, blocks autoimmunity, and promotes suppressor phenomena in NOD mice. , 1997, Journal of immunology.
[61] J. Petersen,et al. A cholera toxoid-insulin conjugate as an oral vaccine against spontaneous autoimmune diabetes. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[62] L. Chatenoud,et al. CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice. , 1997, Journal of immunology.
[63] L. Harrison,et al. Aerosol Insulin Induces Regulatory CD8 γδ T Cells That Prevent Murine Insulin-dependent Diabetes , 1996, The Journal of experimental medicine.
[64] S. Henderson,et al. Prevention of a Thl Disease by a Thl, Cytokine: IL‐12 and Diabetes in, NOD Mice , 1996 .
[65] H. Jun,et al. A new type of CD4+ suppressor T cell completely prevents spontaneous autoimmune diabetes and recurrent diabetes in syngeneic islet-transplanted NOD mice. , 1996, Journal of autoimmunity.
[66] J. Peterson,et al. Transfer of Diabetes in the NOD-scid Mouse by CD4 T-Cell Clones: Differential Requirement for CD8 T-Cells , 1996, Diabetes.
[67] C. Thivolet,et al. Active Suppression of Diabetes after Oral Administration of Insulin Is Determined by Antigen Dosage , 1996, Annals of the New York Academy of Sciences.
[68] H. Weiner,et al. Oral Insulin Does Not Prevent Insulin‐dependent Diabetes Melltus in BB Rats , 1996, Annals of the New York Academy of Sciences.
[69] K. Amano,et al. Administration of monoclonal antibodies against vascular cell adhesion molecule-1/very late antigen-4 abrogates predisposing autoimmune diabetes in NOD mice. , 1995, Cellular immunology.
[70] J. Ferrara,et al. CD4+ beta islet cell-reactive T cell clones that suppress autoimmune diabetes in nonobese diabetic mice , 1995, The Journal of experimental medicine.
[71] A. Cooke,et al. In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice. , 1995, The Journal of clinical investigation.
[72] C Benoist,et al. T helper cell subsets in insulin-dependent diabetes. , 1995, Science.
[73] J. Bluestone,et al. Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse , 1995, The Journal of experimental medicine.
[74] J. Krischer,et al. Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcription. , 1995, The Journal of clinical investigation.
[75] L. Adorini,et al. Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice , 1995, The Journal of experimental medicine.
[76] R. Tisch,et al. Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process , 1994, The Journal of experimental medicine.
[77] M. Monahan,et al. Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse. , 1994, Clinical immunology and immunopathology.
[78] L. Chatenoud,et al. Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[79] A. Signore,et al. Tolbutamide reduces the incidence of diabetes mellitus, but not insulitis, in the non-obese-diabetic mouse , 1993, Diabetologia.
[80] J. Sredy,et al. Rapamycin prevents the onset of insulin‐dependent diabetes mellitus (IDDM) in NOD mice , 1992, Clinical and experimental immunology.
[81] G. Soma,et al. Homeostasis as regulated by activated macrophage. V. Suppression of diabetes mellitus in non-obese diabetic mice by LPSw (a lipopolysaccharide from wheat flour). , 1992, Chemical & pharmaceutical bulletin.
[82] T. Maki,et al. Long-term abrogation of autoimmune diabetes in nonobese diabetic mice by immunotherapy with anti-lymphocyte serum. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[83] A. Hayward,et al. Reduced incidence of insulitis in NOD mice following anti-CD3 injection: requirement for neonatal injection. , 1992, Journal of autoimmunity.
[84] J. Satoh,et al. Inhibition of autoimmune diabetes in NOD mice with serum from streptococcal preparation (OK‐432)‐injected mice , 1991, Clinical and experimental immunology.
[85] H. Weiner,et al. Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin. , 1991 .
[86] M. Matsumoto,et al. Possible mechanism of the preventive effect of BCG against diabetes mellitus in NOD mouse. II. Suppression of pathogenesis by macrophage transfer from BCG-vaccinated mice. , 1991, Cellular immunology.
[87] P. Bedossa,et al. CD8+ T cell homing to the pancreas in the nonobese diabetic mouse is CD4+ T cell-dependent. , 1991, Journal of immunology.
[88] R. Elliott,et al. Early nicotinamide treatment in the NOD mouse: effects on diabetes and insulitis suppression and autoantibody levels. , 1990, Diabetes research.
[89] K. Haskins,et al. Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone. , 1990, Science.
[90] M. Atkinson,et al. Insulitis and Diabetes in NOD Mice Reduced by Prophylactic Insulin Therapy , 1990, Diabetes.
[91] H. Mcdevitt,et al. Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[92] J. Satoh,et al. Recombinant human tumor necrosis factor alpha suppresses autoimmune diabetes in nonobese diabetic mice. , 1989, The Journal of clinical investigation.
[93] A. Hayward,et al. Neonatal injection of CD3 antibody into nonobese diabetic mice reduces the incidence of insulitis and diabetes. , 1989, Journal of immunology.
[94] C. Fathman,et al. Immunotherapy of the nonobese diabetic mouse: treatment with an antibody to T-helper lymphocytes. , 1988, Science.
[95] C. Boitard,et al. Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells , 1987, The Journal of experimental medicine.
[96] M. Suko,et al. Preventive effects of Cyclosporin on diabetes in NOD mice , 1986, Diabetologia.
[97] T. Hanafusa,et al. Preventive and Therapeutic Effects of Large-Dose Nicotinamide Injections on Diabetes Associated with Insulitis: An Observation in Nonobese Diabetic (NOD) Mice , 1982, Diabetes.
[98] Y. Tochino,et al. Breeding of a non-obese, diabetic strain of mice. , 1980, Jikken dobutsu. Experimental animals.
[99] Mark S. Anderson,et al. The NOD mouse: a model of immune dysregulation. , 2005, Annual review of immunology.
[100] D. Greiner,et al. Rat models of type 1 diabetes: genetics, environment, and autoimmunity. , 2004, ILAR journal.
[101] M. Atkinson,et al. Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice , 2004, Gene Therapy.
[102] Simon C Watkins,et al. Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advanced insulitis. , 2003, Human gene therapy.
[103] Peter Lipsky,et al. Cytokines and autoimmunity , 2002, Nature Reviews Immunology.
[104] J. Bluestone,et al. Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation. , 2001, Annual review of immunology.
[105] L. Chatenoud,et al. Tolerance to islet autoantigens in type 1 diabetes. , 2001, Annual review of immunology.
[106] N. Maclaren,et al. Effect of oral and intravenous insulin and glutamic acid decarboxylase in NOD mice. , 1997, Autoimmunity.
[107] J. B. Classen,et al. The timing of immunization affects the development of diabetes in rodents. , 1996, Autoimmunity.
[108] A. Signore,et al. Standardizing experiments with NOD mice. , 1996, Autoimmunity.
[109] L. Chatenoud,et al. [Remission of established disease in diabetic NOD mice induced by anti-CD3 monoclonal antibody]. , 1992, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.
[110] N. Doll,et al. High dose nicotinamide fails to prevent diabetes in BB rats. , 1989, Autoimmunity.