Pt-Pb nanowire array electrode for enzyme-free glucose detection.

Pt-Pb nanowire array was directly synthesized by electrochemical deposition of Pt-Pb alloy into the pores of microporous polycarbonate template and subsequent chemical etching of the template. The morphology and the composition of the Pt-Pb nanowires were characterized by scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS), respectively. Cyclic voltammetry (CV) was used to evaluate the electrochemical performance of the Pt-Pb nanowire array electrode (Pt-PbNAE). Direct glucose oxidation on Pt-PbNAE was investigated in detail by discussing the effect of the structure and materials of the electrode on electrocatalytic oxidation of glucose. As a result, we found that the Pt-PbNAE with a three-dimensional structure exhibited high electrocatalytic activity to glucose oxidation in neutral condition and could be used for the development of nonenzymatic glucose sensor. To effectively avoid the interference coming from ascorbic acid, a negative potential of -0.20V was chosen for glucose detection, and the sensitivity of the sensor to glucose oxidation was 11.25 microAmM(-1)cm(-2) with a linearity up to 11 mM, and a detection limit of 8 microM (signal-to-noise ratio of 3).

[1]  Sophie Demoustier-Champagne,et al.  Flow injection amperometric detection at enzyme-modified gold nanoelectrodes , 2004 .

[2]  Fwu-Shan Sheu,et al.  Selective and sensitive electrochemical detection of glucose in neutral solution using platinum-lead alloy nanoparticle/carbon nanotube nanocomposites. , 2007, Analytica chimica acta.

[3]  Yu.B. Vassilyev,et al.  Kinetics and mechanism of glucose electrooxidation on different electrode-catalysts: Part I. Adsorption and oxidation on platinum , 1985 .

[4]  P. Ugo,et al.  3D-Ensembles of Gold Nanowires: Preparation, Characterization and Electroanalytical Peculiarities , 2007 .

[5]  Ernest Yeager,et al.  Electrochemical oxidation of glucose on single crystal gold surfaces , 1989 .

[6]  Kang Wang,et al.  Highly Ordered Platinum‐Nanotubule Arrays for Amperometric Glucose Sensing , 2005 .

[7]  G. Wittstock,et al.  Glucose oxidation at bismuth-modified platinum electrodes , 1998 .

[8]  Shana O Kelley,et al.  Electrocatalytic detection of pathogenic DNA sequences and antibiotic resistance markers. , 2003, Analytical chemistry.

[9]  F. Battaglini,et al.  Intramolecular electron-transfer rates in ferrocene-derivatized glucose oxidase , 1993 .

[10]  G. Kokkinidis,et al.  Comparative study of the electrocatalytic influence of underpotential heavy metal adatoms on the anodic oxidation of monosaccharides on Pt in acid solutions , 1985 .

[11]  B. Beden,et al.  Fourier transform infrared reflectance spectroscopic investigation of the electrocatalytic oxidation of d-glucose: Identification of reactive intermediates and reaction products , 1996 .

[12]  F. Battaglini,et al.  Electrochemical study of sulphonated ferrocenes as redox mediators in enzyme electrodes , 1990 .

[13]  Jun Li,et al.  The fabrication and electrochemical characterization of carbon nanotube nanoelectrode arrays , 2004 .

[14]  Wei-Hua Huang,et al.  Carbon fiber nanoelectrodes modified by single-walled carbon nanotubes. , 2003, Analytical chemistry.

[15]  In-Hyeong Yeo,et al.  Anodic response of glucose at copper-based alloy electrodes , 2000 .

[16]  T. Mallouk,et al.  Combinatorial discovery of alloy electrocatalysts for amperometric glucose sensors. , 2001, Analytical chemistry.

[17]  I. Taniguchi,et al.  Electrocatalytic oxidation of glucose at gold nanoparticle-modified carbon electrodes in alkaline and neutral solutions , 2005 .

[18]  Rupert Huber,et al.  TEMPLATE SYNTHESIS OF NANOWIRES IN POROUS POLYCARBONATE MEMBRANES: ELECTROCHEMISTRY AND MORPHOLOGY , 1997 .

[19]  Fwu-Shan Sheu,et al.  Pt–Pb alloy nanoparticle/carbon nanotube nanocomposite: a strong electrocatalyst for glucose oxidation , 2006 .

[20]  Bruce Dunn,et al.  Three-dimensional battery architectures. , 2004, Chemical reviews.

[21]  A. Turner,et al.  Glucose oxidase: an ideal enzyme , 1992 .

[22]  Qin Xu,et al.  Preparation of functionalized copper nanoparticles and fabrication of a glucose sensor , 2006 .

[23]  B. Jena,et al.  Enzyme-free amperometric sensing of glucose by using gold nanoparticles. , 2006, Chemistry.

[24]  G. Bang,et al.  Electrocatalytic oxidation of sugars on silver-UPD single crystal gold electrodes in alkaline solutions , 2003 .

[25]  Wei Gao,et al.  Nonenzymatic glucose detection by using a three-dimensionally ordered, macroporous platinum template. , 2005, Chemistry.

[26]  S. Piletsky,et al.  In vitro diagnostics in diabetes: meeting the challenge. , 1999, Clinical chemistry.

[27]  C. H. Hamann,et al.  The electrooxidation of glucose in phosphate buffer solutions , 1979 .

[28]  G. Rivas,et al.  Glucose microsensor based on electrochemical deposition of iridium and glucose oxidase onto carbon fiber electrodes , 1997 .

[29]  Charles R. Martin,et al.  Preparation and electrochemical characterization of ultramicroelectrode ensembles , 1987 .

[30]  Sejin Park,et al.  Nonenzymatic glucose detection using mesoporous platinum. , 2003, Analytical chemistry.

[31]  Isao Taniguchi,et al.  Effect of metal ad-layers on Au(111) electrodes on electrocatalytic oxidation of glucose in an alkaline solution , 2004 .

[32]  Sophie Demoustier-Champagne,et al.  Bienzyme HRP-GOx-modified gold nanoelectrodes for the sensitive amperometric detection of glucose at low overpotentials. , 2005, Biosensors & bioelectronics.

[33]  Amperometric Glucose Biosensor Based on Gold‐Dispersed Carbon Paste , 1998 .

[34]  A. Tseung,et al.  Partial oxidation of glucose by a Pt|WO3 electrode , 1997 .

[35]  Sejin Park,et al.  Electrochemical non-enzymatic glucose sensors. , 2006, Analytica chimica acta.

[36]  Ernest Yeager,et al.  In situ infrared studies of glucose oxidation on platinum in an alkaline medium , 1991 .

[37]  G. S. Wilson,et al.  Can continuous glucose monitoring be used for the treatment of diabetes. , 1992, Analytical chemistry.

[38]  John H. T. Luong,et al.  Electrochemical detection of carbohydrates using copper nanoparticles and carbon nanotubes , 2004 .

[39]  Shana O Kelley,et al.  Ultrasensitive electrocatalytic DNA detection at two- and three-dimensional nanoelectrodes. , 2004, Journal of the American Chemical Society.

[40]  M. Freund,et al.  Potentiometric sensors based on the inductive effect on the pK(a) of poly(aniline): a nonenzymatic glucose sensor. , 2001, Journal of the American Chemical Society.

[41]  N. Mano,et al.  Characteristics of a miniature compartment-less glucose-O2 biofuel cell and its operation in a living plant. , 2003, Journal of the American Chemical Society.

[42]  E. Yeager,et al.  Electrochemical Oxidation of Glucose on Single Crystal and Polycrystalline Gold Surfaces in Phosphate Buffer , 1996 .

[43]  C. Breslin,et al.  Oxidation and photo-induced oxidation of glucose at a polyaniline film modified by copper particles , 2004 .

[44]  Itamar Willner,et al.  A non-compartmentalized glucose ∣ O2 biofuel cell by bioengineered electrode surfaces , 1999 .