Synthesis and Characterization of Six New Carbazolyl Porphyrins

Novel 4-(N-carbazole methyl) benzoic acid and N-carbazolacetic acid are synthesized, then six new carbazolyl porphyrins are synthesized by bonding these acids to hydroxy porphyrin or amido porphyrin via acyl chloride or N,N′-dicyclohexylcarbodiimide (DCC)–dimethylaminopyndine methods. The formations of these title compounds, as well as their intermediates are characterized by 1H NMR, mass spectrometry, Fourier transform–infrared, and elemental analysis.

[1]  Hongbing Ji,et al.  Rapid Synthesis of Alkyloxy Porphyrins Under Microwave Irradiation , 2008 .

[2]  Smita Rai,et al.  Synthesis of covalently linked unsymmetrical porphyrin pentads containing three different porphyrin subunits. , 2008, The Journal of organic chemistry.

[3]  A. Yuchi,et al.  Two-phase reactions of tin(IV)-tetraphenylporphine complexes as carrier of anion selective electrodes , 2008 .

[4]  A. Rescigno,et al.  5,10,15,20-tetrakis(4-sulfonato-phenyl)porphine-Mn(III) immobilized on imidazole-activated silica as a novel lignin-peroxidase-like biomimetic catalyst , 2007 .

[5]  Z. Jia,et al.  Synthesis and preliminary biological studies of the novel conjugate 188Re-labeled meso-tetrakis(4-sulfophenyl)porphyrin in mice. , 2007, Nuclear medicine and biology.

[6]  K. Berg,et al.  Y1068 phosphorylation is the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor. , 2007, Biochemical pharmacology.

[7]  F. Cheng,et al.  Study on spectroscopic characterization of meso-tetrakis (4-hydroxyphenyl) porphyrin (THPP) in β-cyclodextrin and its derivatives , 2005 .

[8]  K. K. Hii,et al.  Chemoselective epoxidation of dienes using polymer-supported manganese porphyrin catalysts , 2004 .

[9]  Can-cheng Guo,et al.  Chloroalkyl piperazine and nitrogen mustard porphyrins: synthesis and anticancer activity. , 2004, Bioorganic & medicinal chemistry.

[10]  P. Liu,et al.  Synthesis of N-protected amino acid trifluoroethyl esters catalyzed by 4-dimethylaminopyridine , 2001 .

[11]  M. Kochanny,et al.  Regiospecific aryl nitration of meso-substituted tetraarylporphyrins: a simple route to bifunctional porphyrins , 1989 .

[12]  P. Rothemund,et al.  Porphyrin Studies. IV.1 The Synthesis of α,β,γ,δ-Tetraphenylporphine , 1941 .