Treatment of benign and low-grade malignant intramedullary chondroid tumours with curettage and cryosurgery.

AIMS To shed light on the controversy surrounding the methods of evaluating, staging and final treatment of intramedullary chondroid lesions. Controversy particularly exists for enchondroma and low-grade chondrosarcoma located in the extremities, because their accurate distinction is hampered by their radiographical and histological similarity. METHODS Since 1991 we have treated 22 patients (mean age: 39.6 years) with 26 lesions (three chondroblastomas, 14 enchondromas and nine grade 1 chondrosarcomas) with curettage, cryosurgery and bone grafting. RESULTS After a mean follow-up of 26 months no recurrences were observed. Complications consisted of two post-operative fractures, one wound infection and one intraoperative venous gas embolism. All bone grafts incorporated, resulting in full weight-bearing capacity and excellent functional results. CONCLUSION The usefulness of a combination of curettage and cryosurgery as adjuvant therapy is considered to be equal to marginal resection according to orthopaedic oncological principles. The pre-operative assessment of these lesions and cryosurgical technique is described in detail.

[1]  W. Molenaar,et al.  Aneurysmal bone cysts treated by curettage, cryotherapy and bone grafting. , 1997, The Journal of bone and joint surgery. British volume.

[2]  E. van den Berg,et al.  Cytogenetics as a tool in the histologic subclassification of chondrosarcomas. , 1994, Cancer genetics and cytogenetics.

[3]  A. Schepper,et al.  Magnetic resonance imaging of cartilaginous tumors: is it useful or necessary? , 1996, Skeletal Radiology.

[4]  D A Whalen,et al.  Effect of varying freezing and thawing rates in experimental cryosurgery. , 1985, Cryobiology.

[5]  R. Marcove,et al.  The Treatment of Aneurysmal Bone Cyst , 1995, Clinical orthopaedics and related research.

[6]  A. Roessner,et al.  Bone tumors of the hand , 1987, Archives of orthopaedic and traumatic surgery.

[7]  K. Unni,et al.  Dahlin's Bone Tumors: General Aspects and Data on 11,087 Cases , 1996 .

[8]  S. Sone,et al.  MR of enchondroma and chondrosarcoma: rings and arcs of Gd-DTPA enhancement. , 1991, Journal of computer assisted tomography.

[9]  W. Enneking Musculoskeletal tumor surgery , 1983 .

[10]  H. Schwartz,et al.  The malignant potential of enchondromatosis. , 1987, The Journal of bone and joint surgery. American volume.

[11]  P. A. Jacobs,et al.  The closed cryosurgical treatment of giant cell tumor. , 1985, Clinical orthopaedics and related research.

[12]  R. Marcove,et al.  The use of cryosurgery in the treatment of low and medium grade chondrosarcoma. A preliminary report. , 1977, Clinical orthopaedics and related research.

[13]  N. Sanerkin,et al.  A review of the behaviour of chondrosarcoma of bone. , 1979, The Journal of bone and joint surgery. British volume.

[14]  G. Lodwick The radiologist's role in the management of chondrosarcoma. , 1984, Radiology.

[15]  R. Marcove A 17-year review of cryosurgery in the treatment of bone tumors. , 1982, Clinical orthopaedics and related research.

[16]  W. Enneking A system of staging musculoskeletal neoplasms. , 1986, Clinical orthopaedics and related research.

[17]  U. Quint,et al.  Surgical treatment of enchondroma in long tubular bones , 1995, Archives of Orthopaedic and Trauma Surgery.

[18]  W. Enneking,et al.  A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. , 1993, Clinical orthopaedics and related research.

[19]  G. Meachim Histological grading of chondrosarcomata. , 1979, The Journal of bone and joint surgery. British volume.

[20]  N. Sanerkin,et al.  The diagnosis and grading of chondrosarcoma of bone a combined cytologic and histologic approach , 1980 .

[21]  R. Moser,et al.  Cartilaginous bone tumors. , 1993, Radiologic clinics of North America.

[22]  A. Gage Cryo Corner: What Temperature Is Lethal for Cells? , 1979 .

[23]  M. Campanacci Bone and Soft Tissue Tumors , 1990 .

[24]  R. Reid New developments in the diagnosis of chondrosarcoma , 1991, The Journal of pathology.

[25]  A. Kreicbergs,et al.  Low risk of recurrence of enchondroma and low-grade chondrosarcoma in extremities. 80 patients followed for 2-25 years. , 1995, Acta orthopaedica Scandinavica.