Novel HIV-1 Knockdown Targets Identified by an Enriched Kinases/Phosphatases shRNA Library Using a Long-Term Iterative Screen in Jurkat T-Cells
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Nir Hacohen | Catarina Moita | N. Hacohen | Sylvie Rato | J. Moniz-Pereira | L. Moita | Carina F. Pereira | Joao Goncalves | Rui P. Freitas | P. Brito | Sylvie Rato | Luis Ferreira Moita | Sara Maia | Paula M. Brito | Leonor Resende | José Moniz-Pereira | C. Moita | S. Maia | J. Gonçalves | Rui Freitas | Leonor Resende | Catarina F Moita
[1] M. Giacca,et al. Extracellular HIV-1 Tat protein differentially activates the JNK and ERK/MAPK pathways in CD4 T cells. , 1999, AIDS.
[2] Narasimhan J. Venkatachari,et al. Antiviral effects of mifepristone on human immunodeficiency virus type-1 (HIV-1): targeting Vpr and its cellular partner, the glucocorticoid receptor (GR). , 2006, Antiviral research.
[3] M. Malim,et al. Human Immunodeficiency Virus Type 1 Spinoculation Enhances Infection through Virus Binding , 2000, Journal of Virology.
[4] Pauline E. Chugh,et al. Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy , 2008, Retrovirology.
[5] P. Pitha,et al. Exploitation of cellular signaling by HIV-1: unwelcome guests with master keys that signal their entry. , 2000, Virology.
[6] L. Selig,et al. HEED, the Product of the Human Homolog of the Murineeed Gene, Binds to the Matrix Protein of HIV-1* , 1999, The Journal of Biological Chemistry.
[7] L. Mullenders,et al. Nucleotide excision repair and its interplay with transcription. , 2003, Toxicology.
[8] B. Hemmings,et al. NDR family of AGC kinases – essential regulators of the cell cycle and morphogenesis , 2003, FEBS letters.
[9] Donna R. Maglott,et al. Human immunodeficiency virus type 1, human protein interaction database at NCBI , 2008, Nucleic Acids Res..
[10] F. Hanaoka,et al. Human immunodeficiency virus type 1 Vpr interacts with HHR23A, a cellular protein implicated in nucleotide excision DNA repair , 1997, Journal of virology.
[11] G. Chrousos,et al. HHR23A, the human homologue of the yeast repair protein RAD23, interacts specifically with Vpr protein and prevents cell cycle arrest but not the transcriptional effects of Vpr. , 1998, Virology.
[12] D. Margolis,et al. Hexamethylbisacetamide and disruption of human immunodeficiency virus type 1 latency in CD4(+) T cells. , 2008, The Journal of infectious diseases.
[13] A. Hopkins,et al. The druggable genome , 2002, Nature Reviews Drug Discovery.
[14] A. Dayton,et al. Hitting HIV where it hides , 2008, Retrovirology.
[15] S. Lampel,et al. The druggable genome: an update. , 2005, Drug discovery today.
[16] Charles Flexner,et al. HIV drug development: the next 25 years , 2007, Nature Reviews Drug Discovery.
[17] W. Greene,et al. Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy , 2002, Nature Medicine.
[18] S. Goff,et al. Host factors exploited by retroviruses , 2007, Nature Reviews Microbiology.
[19] J. Loffing,et al. Sgk kinases and their role in epithelial transport. , 2006, Annual review of physiology.
[20] A. Greenway,et al. HIV-1 Nef control of cell signalling molecules: Multiple strategies to promote virus replication , 2003, Journal of Biosciences.
[21] M. Ott,et al. HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane. , 2004, Molecular cell.
[22] V. Trouplin,et al. Retracing the Evolutionary Pathways of Human Immunodeficiency Virus Type 1 Resistance to Protease Inhibitors: Virus Fitness in the Absence and in the Presence of Drug , 2000, Journal of Virology.
[23] Amy S. Espeseth,et al. Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies , 2009, PLoS pathogens.
[24] H. Enslen,et al. Modulation of HIV‐1 infectivity by MAPK, a virion–associated kinase , 1998, The EMBO journal.
[25] D. Weiner,et al. Human immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanism , 2005, Cell Death and Differentiation.
[26] R. König,et al. Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication , 2008, Cell.
[27] D. Gabuzda,et al. ERK MAP Kinase Links Cytokine Signals to Activation of Latent HIV-1 Infection by Stimulating a Cooperative Interaction of AP-1 and NF-κB* , 1999, The Journal of Biological Chemistry.
[28] Pamela A Silver,et al. HIV-1 incorporates and proteolytically processes human NDR1 and NDR2 serine-threonine kinases. , 2005, Virology.
[29] David Baltimore,et al. Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors , 2002, Science.
[30] R. Kole,et al. HIV-1 preferentially binds receptors copatched with cell-surface elastase. , 2003, Blood.
[31] J. Lieberman,et al. Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen , 2007, Science.
[32] M. Geng,et al. Sulfated polymannuroguluronate, a novel anti‐acquired immune deficiency syndrome drug candidate, blocks neuroinflammatory signalling by targeting the transactivator of transcription (Tat) protein , 2006, Journal of neurochemistry.
[33] K. Kok,et al. siRNA and shRNA screens advance key understanding of host factors required for HIV-1 replication , 2009, Retrovirology.
[34] T. Hunter,et al. Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling , 1995, Cell.
[35] M. Stevenson. Can HIV be cured? , 2008, Scientific American.
[36] P. André,et al. Human Polycomb group EED protein negatively affects HIV-1 assembly and release , 2007, Retrovirology.
[37] Ashok Kumar,et al. Activation of JNK-dependent pathway is required for HIV viral protein R-induced apoptosis in human monocytic cells. INVOLVEMENT OF ANTIAPOPTOTIC BCL2 AND c-IAP1 GENES. , 2012, The Journal of Biological Chemistry.
[38] S. Nekhai,et al. REGULATION OF HIV‐1 TRANSCRIPTION BY PROTEIN PHOSPHATASE 1 , 2006, Current HIV research.
[39] J. Sodroski,et al. CD4-Induced Conformational Changes in the Human Immunodeficiency Virus Type 1 gp120 Glycoprotein: Consequences for Virus Entry and Neutralization , 1998, Journal of Virology.
[40] L. Naldini,et al. Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters , 2005, Nature Biotechnology.
[41] Amy S. Espeseth,et al. Genome-scale RNAi screen for host factors required for HIV replication. , 2008, Cell host & microbe.
[42] Philip Cohen. 25 years with HIV , 2006 .
[43] Kuan-Teh Jeang,et al. A Genome-wide Short Hairpin RNA Screening of Jurkat T-cells for Human Proteins Contributing to Productive HIV-1 Replication* , 2009, The Journal of Biological Chemistry.
[44] J. Chai,et al. Structural basis of EZH2 recognition by EED. , 2007, Structure.
[45] J. Mouscadet,et al. The Human Polycomb Group EED Protein Interacts with the Integrase of Human Immunodeficiency Virus Type 1 , 2003, Journal of Virology.
[46] S. Goff,et al. Knockdown Screens to Knockout HIV-1 , 2008, Cell.