A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 2.
暂无分享,去创建一个
[1] G. Torres,et al. Distribution Analysis of Deacetylase SIRT1 in Rodent and Human Nervous Systems , 2010, Anatomical record.
[2] Jianping Ye,et al. Lack of SIRT1 (Mammalian Sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: a role of lipid mobilization and inflammation. , 2010, Endocrinology.
[3] Ming-Ming Zhou,et al. p53-Induced Growth Arrest Is Regulated by the Mitochondrial SirT3 Deacetylase , 2010, PloS one.
[4] M. Vinciguerra,et al. SirT1 in muscle physiology and disease: lessons from mouse models , 2010, Disease Models & Mechanisms.
[5] Christian Neri,et al. SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis , 2010, Proceedings of the National Academy of Sciences.
[6] E. Lam,et al. SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2 , 2010, Molecular Cancer Therapeutics.
[7] Y. Kanfi,et al. SIRT6 protects against pathological damage caused by diet‐induced obesity , 2010, Aging cell.
[8] R. Margis,et al. SIRT1 Transcription Is Decreased in Visceral Adipose Tissue of Morbidly Obese Patients with Severe Hepatic Steatosis , 2010, Obesity surgery.
[9] Ruth I. Tennen,et al. Functional dissection of SIRT6: Identification of domains that regulate histone deacetylase activity and chromatin localization , 2010, Mechanisms of Ageing and Development.
[10] M. Periasamy,et al. Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy. , 2010, American journal of physiology. Heart and circulatory physiology.
[11] I. Rahman,et al. SIRT1 regulates oxidant- and cigarette smoke-induced eNOS acetylation in endothelial cells: Role of resveratrol. , 2010, Biochemical and biophysical research communications.
[12] S. Xiao,et al. SIRT3 reduces lipid accumulation via AMPK activation in human hepatic cells , 2010, Journal of digestive diseases.
[13] Yuzhi Zhang,et al. Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype. , 2010, Cardiovascular research.
[14] B. Knöll,et al. SIRT2-mediated protein deacetylation: An emerging key regulator in brain physiology and pathology. , 2010, European journal of cell biology.
[15] G. Gores,et al. Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. , 2010, The Journal of clinical investigation.
[16] M. Laakso,et al. SIRT1 mRNA Expression May Be Associated With Energy Expenditure and Insulin Sensitivity , 2010, Diabetes.
[17] Orian S. Shirihai,et al. The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α , 2010, Cell.
[18] K. Shimamoto,et al. Induction of Manganese Superoxide Dismutase by Nuclear Translocation and Activation of SIRT1 Promotes Cell Survival in Chronic Heart Failure* , 2010, The Journal of Biological Chemistry.
[19] C. Deng,et al. SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. , 2010, Cancer cell.
[20] C. Cobelli,et al. Downregulation of the Longevity-Associated Protein Sirtuin 1 in Insulin Resistance and Metabolic Syndrome: Potential Biochemical Mechanisms , 2010, Diabetes.
[21] Nektarios Tavernarakis,et al. The life span-prolonging effect of Sirtuin-1 is mediated by autophagy , 2010, Autophagy.
[22] Young A Lee,et al. Persimmon oligomeric proanthocyanidins extend life span of senescence-accelerated mice. , 2009, Journal of medicinal food.
[23] C. Vaslet,et al. Hypothalamic Sirt1 Regulates Food Intake in a Rodent Model System , 2009, PloS one.
[24] Nektarios Tavernarakis,et al. Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol , 2009, Aging.
[25] Cuk-Seong Kim,et al. SIRT1 deacetylates APE1 and regulates cellular base excision repair , 2009, Nucleic acids research.
[26] B. Viollet,et al. AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol , 2009, Diabetes.
[27] K. Tsuneyama,et al. Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice. , 2009, American journal of physiology. Endocrinology and metabolism.
[28] H. Hara,et al. Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection. , 2009, Biochemical and biophysical research communications.
[29] M. Pallàs,et al. Anti‐aging properties of melatonin in an in vitro murine senescence model: involvement of the sirtuin 1 pathway , 2009, Journal of pineal research.
[30] Un-In Wu,et al. Melatonin preserves longevity protein (sirtuin 1) expression in the hippocampus of total sleep‐deprived rats , 2009, Journal of pineal research.
[31] S. Stürzenbaum,et al. Quercetin mediated lifespan extension in Caenorhabditis elegans is modulated by age-1, daf-2, sek-1 and unc-43 , 2009, Biogerontology.
[32] Gene Kim,et al. Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. , 2009, The Journal of clinical investigation.
[33] Q. Tong,et al. Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle , 2009, Aging.
[34] M. McBurney,et al. SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol , 2009, Oncogene.
[35] M. Federici,et al. TIMP3 Is Reduced in Atherosclerotic Plaques From Subjects With Type 2 Diabetes and Increased by SirT1 , 2009, Diabetes.
[36] Daisuke Koya,et al. SIRT1 and insulin resistance , 2009, Nature Reviews Endocrinology.
[37] A. Purushotham,et al. SIRT1 performs a balancing act on the tight-rope toward longevity , 2009, Aging.
[38] K. Jang,et al. Expression of DBC1 and SIRT1 Is Associated with Poor Prognosis of Gastric Carcinoma , 2009, Clinical Cancer Research.
[39] J. Bennett,et al. Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway. , 2009, Free radical biology & medicine.
[40] I. Komuro,et al. Protective Role of SIRT1 in Diabetic Vascular Dysfunction , 2009, Arteriosclerosis, thrombosis, and vascular biology.
[41] Jane-ling Wang,et al. The prolongevity effect of resveratrol depends on dietary composition and calorie intake in a tephritid fruit fly , 2009, Experimental Gerontology.
[42] K. Birukov,et al. SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1 , 2009, Molecular and Cellular Biology.
[43] B. Jung-Hynes,et al. Role of p53 in the anti-proliferative effects of Sirt1 inhibition in prostate cancer cells , 2009, Cell cycle.
[44] T. Yeatman,et al. SirT1 Is an Inhibitor of Proliferation and Tumor Formation in Colon Cancer* , 2009, The Journal of Biological Chemistry.
[45] C. Bäckesjö,et al. Resveratrol inhibits proliferation and promotes apoptosis of osteosarcoma cells. , 2009, European journal of pharmacology.
[46] D. Della-Morte,et al. Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1–uncoupling protein 2 pathway , 2009, Neuroscience.
[47] M. Mattson,et al. Nicotinamide Prevents NAD+ Depletion and Protects Neurons Against Excitotoxicity and Cerebral Ischemia: NAD+ Consumption by SIRT1 may Endanger Energetically Compromised Neurons , 2009, NeuroMolecular Medicine.
[48] Yu-cai Fu,et al. Resveratrol inhibits the expression of SREBP1 in cell model of steatosis via Sirt1-FOXO1 signaling pathway. , 2009, Biochemical and biophysical research communications.
[49] C. Liu,et al. Porcine sirtuin 1 gene clone, expression pattern, and regulation by resveratrol. , 2009, Journal of animal science.
[50] M. Yamakuchi,et al. MiR-34, SIRT1, and p53: The feedback loop , 2009, Cell cycle.
[51] D. Das,et al. Expression of the longevity proteins by both red and white wines and their cardioprotective components, resveratrol, tyrosol, and hydroxytyrosol. , 2009, Free radical biology & medicine.
[52] D. Hernandez-Verdun,et al. Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis , 2009, Journal of Cell Science.
[53] B. Jung-Hynes,et al. Role of Sirtuin Histone Deacetylase SIRT1 in Prostate Cancer , 2009, Journal of Biological Chemistry.
[54] Ji‐Hyun Lee,et al. Overexpression of SIRT1 Protects Pancreatic β-Cells Against Cytokine Toxicity by Suppressing the Nuclear Factor-κB Signaling Pathway , 2009, Diabetes.
[55] C. Deng. SIRT1, Is It a Tumor Promoter or Tumor Suppressor? , 2009, International journal of biological sciences.
[56] Yu-cai Fu,et al. Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway. , 2009, Biochemical and biophysical research communications.
[57] Howard Y. Chang,et al. SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span , 2009, Cell.
[58] D. Bennett,et al. Sirtuin 1 Reduction Parallels the Accumulation of Tau in Alzheimer Disease , 2009, Journal of neuropathology and experimental neurology.
[59] D. Lombard. Sirtuins at the Breaking Point: SIRT6 in DNA Repair , 2009, Aging.
[60] S. Guan,et al. SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair , 2009, Aging.
[61] Chi Ma,et al. Opposing Effects of Sirtuins on Neuronal Survival: SIRT1-Mediated Neuroprotection Is Independent of Its Deacetylase Activity , 2008, PloS one.
[62] J. Olefsky,et al. SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes , 2008, Molecular and Cellular Biology.
[63] M. Mattson,et al. Preventing NAD+ Depletion Protects Neurons against Excitotoxicity , 2008, Annals of the New York Academy of Sciences.
[64] Andrew D. Steele,et al. The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration , 2008, Experimental Gerontology.
[65] S. French,et al. Sirt1 is involved in energy metabolism: the role of chronic ethanol feeding and resveratrol. , 2008, Experimental and molecular pathology.
[66] E. Bober,et al. Sirt7-dependent inhibition of cell growth and proliferation might be instrumental to mediate tissue integrity during aging. , 2008, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
[67] F. Alt,et al. SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging , 2008, Cell.
[68] F. LaFerla,et al. Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau , 2008, The Journal of Neuroscience.
[69] M. Pallàs,et al. Evaluation of potential pro‐survival pathways regulated by melatonin in a murine senescence model , 2008, Journal of pineal research.
[70] C. Steegborn,et al. Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5. , 2008, Journal of molecular biology.
[71] C. Deng,et al. Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis. , 2008, Molecular cell.
[72] Alexander S. Banks,et al. SirT1 gain of function increases energy efficiency and prevents diabetes in mice. , 2008, Cell metabolism.
[73] X. Wang,et al. Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. , 2008, Cancer cell.
[74] A. Bookout,et al. Brain SIRT1: Anatomical Distribution and Regulation by Energy Availability , 2008, The Journal of Neuroscience.
[75] Shiwei Song,et al. A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis , 2008, Proceedings of the National Academy of Sciences.
[76] E. Tsiani,et al. Stimulation of muscle cell glucose uptake by resveratrol through sirtuins and AMPK. , 2008, Biochemical and biophysical research communications.
[77] M. Gottesman,et al. SIRT1 Contributes in Part to Cisplatin Resistance in Cancer Cells by Altering Mitochondrial Metabolism , 2008, Molecular Cancer Research.
[78] C. Bäckesjö,et al. Activation of Sirt1 Decreases Adipocyte Formation during Osteoblast Differentiation of Mesenchymal Stem Cells , 2008, Cells Tissues Organs.
[79] N. Sundaresan,et al. SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70 , 2008, Molecular and Cellular Biology.
[80] K. Maiese,et al. Enhanced tolerance against early and late apoptotic oxidative stress in mammalian neurons through nicotinamidase and sirtuin mediated pathways. , 2008, Current neurovascular research.
[81] Fan Lan,et al. SIRT1 Regulates Hepatocyte Lipid Metabolism through Activating AMP-activated Protein Kinase* , 2008, Journal of Biological Chemistry.
[82] P. Pfluger,et al. Sirt1 protects against high-fat diet-induced metabolic damage , 2008, Proceedings of the National Academy of Sciences.
[83] V. Longo,et al. SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons. , 2008, Cell metabolism.
[84] K. Sunagawa,et al. SIRT1, a Longevity Gene, Downregulates Angiotensin II Type 1 Receptor Expression in Vascular Smooth Muscle Cells , 2008, Arteriosclerosis, thrombosis, and vascular biology.
[85] B. Richelsen,et al. Low Sirt1 expression, which is upregulated by fasting, in human adipose tissue from obese women , 2008, International Journal of Obesity.
[86] D. Allison,et al. A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice , 2008, PloS one.
[87] C. Napoli,et al. High glucose downregulates endothelial progenitor cell number via SIRT1. , 2008, Biochimica et biophysica acta.
[88] C. Lieber,et al. Effect of chronic alcohol consumption on Hepatic SIRT1 and PGC-1alpha in rats. , 2008, Biochemical and biophysical research communications.
[89] W. Hahn,et al. The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth , 2008, PloS one.
[90] Min You,et al. Involvement of mammalian sirtuin 1 in the action of ethanol in the liver. , 2008, American journal of physiology. Gastrointestinal and liver physiology.
[91] E. Bober,et al. Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice , 2008, Circulation research.
[92] Howard Y. Chang,et al. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin , 2008, Nature.
[93] Jörg Vervoorts,et al. The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility , 2008, The Journal of cell biology.
[94] Min You,et al. Mammalian sirtuin 1 is involved in the protective action of dietary saturated fat against alcoholic fatty liver in mice. , 2008, The Journal of nutrition.
[95] B. Tang,et al. SIRT2, tubulin deacetylation, and oligodendroglia differentiation. , 2008, Cell motility and the cytoskeleton.
[96] S. Imai,et al. Age‐associated loss of Sirt1‐mediated enhancement of glucose‐stimulated insulin secretion in beta cell‐specific Sirt1‐overexpressing (BESTO) mice , 2008, Aging cell.
[97] J. Qin,et al. Negative regulation of the deacetylase SIRT1 by DBC1 , 2008, Nature.
[98] Andrew D. Steele,et al. SIRT1 transgenic mice show phenotypes resembling calorie restriction , 2007, Aging cell.
[99] Eric Verdin,et al. Regulation of Insulin Secretion by SIRT4, a Mitochondrial ADP-ribosyltransferase* , 2007, Journal of Biological Chemistry.
[100] M. Salto‐Tellez,et al. Function of the SIRT1 protein deacetylase in cancer. , 2007, Biotechnology journal.
[101] J. Milner,et al. SIRT3 is Pro-Apoptotic and Participates in Distinct Basal Apoptotic Pathways , 2007, Cell cycle.
[102] L. Qiang,et al. Identification of a Domain within Peroxisome Proliferator-Activated Receptor γ Regulating Expression of a Group of Genes Containing Fibroblast Growth Factor 21 That Are Selectively Repressed by SIRT1 in Adipocytes , 2007, Molecular and Cellular Biology.
[103] F. Alt,et al. SIRT1 controls endothelial angiogenic functions during vascular growth. , 2007, Genes & development.
[104] L. Guarente,et al. SIRT1 deacetylates and positively regulates the nuclear receptor LXR. , 2007, Molecular cell.
[105] Q. Zhai,et al. SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. , 2007, Cell metabolism.
[106] L. Partridge,et al. Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans , 2007, Mechanisms of Ageing and Development.
[107] Lu Li,et al. Downregulation of Sirt1 by antisense oligonucleotides induces apoptosis and enhances radiation sensitization in A549 lung cancer cells. , 2007, Lung cancer.
[108] W. Pang,et al. Modulation of Sirt1 by resveratrol and nicotinamide alters proliferation and differentiation of pig preadipocytes , 2007, Molecular and Cellular Biochemistry.
[109] Cuk-Seong Kim,et al. SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase , 2007, Proceedings of the National Academy of Sciences.
[110] C. Kahn,et al. SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation. , 2007, Cell metabolism.
[111] Kazuhiko Suzuki,et al. Resveratrol abolishes resistance to axonal degeneration in slow Wallerian degeneration (WldS) mice: activation of SIRT2, an NAD-dependent tubulin deacetylase. , 2007, Biochemical and biophysical research communications.
[112] Ruben Abagyan,et al. Sirtuin 2 Inhibitors Rescue α-Synuclein-Mediated Toxicity in Models of Parkinson's Disease , 2007, Science.
[113] T. Nagy,et al. SIRT1 is significantly elevated in mouse and human prostate cancer. , 2007, Cancer research.
[114] Andre Fischer,et al. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis , 2007, The EMBO journal.
[115] Lulu Chen,et al. The expression of SIRT1 in nonalcoholic fatty liver disease induced by high‐fat diet in rats , 2007, Liver international : official journal of the International Association for the Study of the Liver.
[116] S. Vatner,et al. Sirt1 Regulates Aging and Resistance to Oxidative Stress in the Heart , 2007, Circulation research.
[117] Y. Kubo,et al. Strong expression of a longevity-related protein, SIRT1, in Bowen’s disease , 2007, Archives of Dermatological Research.
[118] Bin Zhang,et al. Sirtuin 2, a Mammalian Homolog of Yeast Silent Information Regulator-2 Longevity Regulator, Is an Oligodendroglial Protein That Decelerates Cell Differentiation through Deacetylating α-Tubulin , 2007, The Journal of Neuroscience.
[119] G. Park,et al. SIRT1 promotes DNA repair activity and deacetylation of Ku70 , 2007, Experimental & Molecular Medicine.
[120] T. Shioi,et al. Resveratrol ameliorates experimental autoimmune myocarditis. , 2007, Circulation journal : official journal of the Japanese Circulation Society.
[121] M. Oshimura,et al. SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress , 2007, Oncogene.
[122] M. Tainsky,et al. Microtubule Deacetylases, SirT2 and HDAC6, in the Nervous System , 2007, Neurochemical Research.
[123] J. Shao,et al. SIRT1 Regulates Adiponectin Gene Expression through Foxo1-C/Enhancer-binding Protein α Transcriptional Complex* , 2006, Journal of Biological Chemistry.
[124] P. Puigserver,et al. Resveratrol improves health and survival of mice on a high-calorie diet , 2006, Nature.
[125] P. Shiels,et al. Altered sirtuin expression is associated with node-positive breast cancer , 2006, British Journal of Cancer.
[126] M. Perez-Pinzon,et al. Resveratrol Mimics Ischemic Preconditioning in the Brain , 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[127] Jun Wang,et al. Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction* , 2006, Journal of Biological Chemistry.
[128] Antonino Cattaneo,et al. Resveratrol Prolongs Lifespan and Retards the Onset of Age-Related Markers in a Short-Lived Vertebrate , 2006, Current Biology.
[129] Kelly M. McGarvey,et al. Inhibition of SIRT1 Reactivates Silenced Cancer Genes without Loss of Promoter DNA Hypermethylation , 2006, PLoS genetics.
[130] Madeleine Lemieux,et al. Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells , 2005, PLoS biology.
[131] Andrew D. Steele,et al. Increase in Activity During Calorie Restriction Requires Sirt1 , 2005, Science.
[132] A. Ho,et al. FISH-mapping and genomic organization of the NAD-dependent histone deacetylase gene, Sirtuin 2 (Sirt2). , 2005, International journal of oncology.
[133] C. Bradbury,et al. Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors , 2005, Leukemia.
[134] M. Permutt,et al. Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice. , 2005, Cell metabolism.
[135] Michael M. Murphy,et al. Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress. , 2005, Cell metabolism.
[136] G. Wilcox. Insulin and insulin resistance. , 2005, The Clinical biochemist. Reviews.
[137] S. Fields,et al. Substrate-specific Activation of Sirtuins by Resveratrol* , 2005, Journal of Biological Chemistry.
[138] Q. Tong,et al. SIRT3, a Mitochondrial Sirtuin Deacetylase, Regulates Mitochondrial Function and Thermogenesis in Brown Adipocytes* , 2005, Journal of Biological Chemistry.
[139] S. Tachiiri,et al. Role of NAD‐dependent deacetylases SIRT1 and SIRT2 in radiation and cisplatin‐induced cell death in vertebrate cells , 2005, Genes to cells : devoted to molecular & cellular mechanisms.
[140] E. Ravussin,et al. Glucose tolerance and skeletal muscle gene expression in response to alternate day fasting. , 2005, Obesity research.
[141] S. Fulda,et al. Sensitization for anticancer drug-induced apoptosis by the chemopreventive agent resveratrol , 2004, Oncogene.
[142] J. Milbrandt,et al. Increased Nuclear NAD Biosynthesis and SIRT1 Activation Prevent Axonal Degeneration , 2004, Science.
[143] J. Wood,et al. Sirtuin activators mimic caloric restriction and delay ageing in metazoans , 2004, Nature.
[144] Namjin Chung,et al. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ , 2004, Nature.
[145] Steven P. Gygi,et al. Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase , 2004, Science.
[146] Phuong Chung,et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan , 2003, Nature.
[147] J. Denu,et al. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. , 2003, Molecular cell.
[148] Delin Chen,et al. Negative Control of p53 by Sir2α Promotes Cell Survival under Stress , 2001, Cell.
[149] Robert V Farese,et al. SIRT 3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation , 2010 .
[150] Physiology.. Mice , 2008 .
[151] L. Peshkin,et al. Supplemental Data Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span , 2008 .
[152] K. Clément,et al. Contribution of energy restriction and macronutrient composition to changes in adipose tissue gene expression during dietary weight-loss programs in obese women. , 2008, The Journal of clinical endocrinology and metabolism.
[153] R. Abagyan,et al. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. , 2007, Science.
[154] B. Thiers. Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6 , 2007 .
[155] L. Guarente,et al. Negative control of p53 by Sir2alpha promotes cell survival under stress. , 2001, Cell.