Brain Stimulation for Combating Alzheimer’s Disease

Alzheimer’s disease (AD) is a devastating disease affecting 5.2 million Americans. As the cause of death between 2000 and 2010, AD increased by 68% (1). The number of individuals developing AD in the United States will rise dramatically in the following decades (2). As AD patients are often resistant to pharmacotherapy, alternative therapeutic strategies are imperative. Non-invasive and non-lesional brain stimulation is a promising therapeutic option that has been attracting increasing attention over the last few years (3–6). Brain stimulation is useful to accelerate diagnosis and treatment (6, 7). This article focuses on advances in cognitive neurorehabilitation via brain stimulation techniques in AD patients to provide insights into a promising ray of hope for AD patients.