From “What Is?” to “What Isn't?” Computational Biology

This year, PLOS Computational Biology is celebrating its 10th birthday. Such a milestone provides an excellent occasion to reflect on the transformation that the field has undergone during the journal’s lifetime, and on the challenging question of where we may expect it to go next. As the leading journal in computational biology, PLOS Computational Biology encompasses the entire discipline and is therefore well placed to narrate this remarkable story. The evolution of the journal tells a rewarding story of success and accomplishment.