Using Virtual Reality for Cognitive Training of the Elderly

There is a pressing demand for improving the quality and efficacy of health care and social support services needed by the world’s growing elderly population, especially by those affected by mild cognitive impairment (MCI) and Alzheimer’s disease (AD)-type early-stage dementia. Meeting that demand can significantly benefit from the deployment of innovative, computer-based applications capable of addressing specific needs, particularly in the area of cognitive impairment mitigation and rehabilitation. In that context, we present here our perspective viewpoint on the use of virtual reality (VR) tools for cognitive rehabilitation training, intended to assist medical personnel, health care workers, and other caregivers in improving the quality of daily life activities of people with MCI and AD. We discuss some effective design criteria and developmental strategies and suggest some possibly useful protocols and procedures. The particular innovative supportive advantages offered by the immersive interactive characteristics inherent to VR technology are discussed.

[1]  W. Thies,et al.  2013 Alzheimer's disease facts and figures , 2013, Alzheimer's & Dementia.

[2]  Jose Luis Monteagudo Capacidades y oportunidades de innovación en TIC para Alzheimer , 2013 .

[3]  Non-pharmacological intervention for memory decline , 2014, Neurobiology of Aging.

[4]  M. Trabucchi,et al.  Outcomes of a computer-based cognitive rehabilitation program on Alzheimer's disease patients compared with those on patients affected by mild cognitive impairment. , 2006, Archives of gerontology and geriatrics.

[5]  Martin Knapp,et al.  Goal-oriented cognitive rehabilitation in early-stage dementia: study protocol for a multi-centre single-blind randomised controlled trial (GREAT) , 2013, Trials.

[6]  S. Gauthier,et al.  Training-related brain plasticity in subjects at risk of developing Alzheimer's disease. , 2011, Brain : a journal of neurology.

[7]  Cheryl L Grady,et al.  Changes in memory processing with age , 2000, Current Opinion in Neurobiology.

[8]  Albert A. Rizzo,et al.  Virtual environment applications in clinical neuropsychology , 2000, Proceedings IEEE Virtual Reality 2000 (Cat. No.00CB37048).

[9]  Kristine Yaffe,et al.  A Cognitive Training Program Based on Principles of Brain Plasticity: Results from the Improvement in Memory with Plasticity‐based Adaptive Cognitive Training (IMPACT) Study , 2009, Journal of the American Geriatrics Society.

[10]  Pedro Rosa-Neto,et al.  Performance testing of a fully automated, Chemiluminescent, beta-amyloid 42 assay , 2013, Alzheimer's & Dementia.

[11]  M. Simard,et al.  Errorless learning and spaced retrieval techniques to relearn instrumental activities of daily living in mild Alzheimer’s disease: A case report study , 2008, Neuropsychiatric disease and treatment.

[12]  Luciano Gamberini,et al.  Controlling Memory Impairment in Elderly Adults Using Virtual Reality Memory Training: A Randomized Controlled Pilot Study , 2010, Neurorehabilitation and neural repair.

[13]  Osvaldo Gervasi,et al.  Nu!RehaVR: virtual reality in neuro tele-rehabilitation of patients with traumatic brain injury and stroke , 2009, Virtual Reality.

[14]  Albert A. Rizzo,et al.  Initial Validation of a Virtual Environment for Assessment of Memory Functioning: Virtual Reality Cognitive Performance Assessment Test , 2008, Cyberpsychology Behav. Soc. Netw..

[15]  Bob Woods,et al.  Nonpharmacological Therapies in Alzheimer’s Disease: A Systematic Review of Efficacy , 2010, Dementia and Geriatric Cognitive Disorders.

[16]  A. Wimo,et al.  The global prevalence of dementia: A systematic review and metaanalysis , 2013, Alzheimer's & Dementia.

[17]  M. Trabucchi,et al.  Efficacy of cognitive rehabilitation in patients with mild cognitive impairment treated with cholinesterase inhibitors , 2007, International journal of geriatric psychiatry.

[18]  Bernhard Buss,et al.  Virtual reality training system for patients with dementia , 2009 .

[19]  Anna Bacon Moore,et al.  Explicit memory training leads to improved memory for face–name pairs in patients with mild cognitive impairment: Results of a pilot investigation , 2008, Journal of the International Neuropsychological Society.

[20]  M. Schmitter-Edgecombe,et al.  Characterizing multiple memory deficits and their relation to everyday functioning in individuals with mild cognitive impairment. , 2009, Neuropsychology.

[21]  D. Harvey,et al.  MCI is Associated With Deficits in Everyday Functioning , 2006, Alzheimer disease and associated disorders.

[22]  Brian Hobbs,et al.  Developing a Virtual Reality-Based Methodology for People with Dementia: A Feasibility Study , 2003, Cyberpsychology Behav. Soc. Netw..

[23]  Kristine Yaffe,et al.  Improvement in Memory with Plasticity‐Based Adaptive Cognitive Training: Results of the 3‐Month Follow‐Up , 2011, Journal of the American Geriatrics Society.

[24]  Nicholas Tarrier,et al.  Virtual reality in mental health : a review of the literature. , 2007, Social psychiatry and psychiatric epidemiology.

[25]  Rosa Maria Esteves Moreira da Costa,et al.  The acceptance of virtual reality devices for cognitive rehabilitation: a report of positive results with schizophrenia , 2004, Comput. Methods Programs Biomed..

[26]  Abdenour Bouzouane,et al.  Serious games in cognitive training for Alzheimer's patients , 2011, 2011 IEEE 1st International Conference on Serious Games and Applications for Health (SeGAH).

[27]  Vince D. Calhoun,et al.  Alterations in Memory Networks in Mild Cognitive Impairment and Alzheimer's Disease: An Independent Component Analysis , 2006, The Journal of Neuroscience.

[28]  Frederick A. Schmitt,et al.  Improving dementia care: The role of screening and detection of cognitive impairment , 2013, Alzheimer's & Dementia.

[29]  M. Schmitter-Edgecombe,et al.  Application of Cognitive Rehabilitation Theory to the Development of Smart Prompting Technologies , 2012, IEEE Reviews in Biomedical Engineering.

[30]  L. Garcia,et al.  A Discussion of the Use of Virtual Reality in Dementia , 2012 .

[31]  Felipe Fregni,et al.  Non-invasive brain stimulation to assess and modulate neuroplasticity in Alzheimer's disease , 2011, Neuropsychological rehabilitation.

[32]  Jeonghun Ku,et al.  A Virtual Reality System for the Assessment and Rehabilitation of the Activities of Daily Living , 2003, Cyberpsychology Behav. Soc. Netw..

[33]  Charles J Duffy,et al.  Detecting navigational deficits in cognitive aging and Alzheimer disease using virtual reality , 2008, Neurology.

[34]  Giuseppe Riva,et al.  Virtual Reality in Psychotherapy: Review , 2005, Cyberpsychology Behav. Soc. Netw..

[35]  J. A. Almendral,et al.  Reorganization of Functional Networks in Mild Cognitive Impairment , 2011, PloS one.

[36]  Malaz Boustani,et al.  Alzheimer's Association recommendations for operationalizing the detection of cognitive impairment during the Medicare Annual Wellness Visit in a primary care setting , 2013, Alzheimer's & Dementia.

[37]  Sylvie Belleville,et al.  Improvement of Episodic Memory in Persons with Mild Cognitive Impairment and Healthy Older Adults: Evidence from a Cognitive Intervention Program , 2006, Dementia and Geriatric Cognitive Disorders.

[38]  G. Riva,et al.  Virtual reality as assessment tool in psychology. , 1997, Studies in health technology and informatics.

[39]  Sergi Grau,et al.  PREVIRNEC: A cognitive telerehabilitation system based on Virtual Environments , 2009, 2009 Virtual Rehabilitation International Conference.

[40]  Francesca Morganti,et al.  Virtual interaction in cognitive neuropsychology , 2004, Cybertherapy.

[41]  C. Neuper,et al.  Virtual reality in neurologic rehabilitation of spatial disorientation , 2013, Journal of NeuroEngineering and Rehabilitation.