Effects of donor age on urinary chemosignals that influence the timing of first oestrus in young female house mice, Mus domesticus.

The effects of donor age on the effectiveness of puberty-influencing urinary chemosignals in wild house mice was tested in a series of 3 experiments. The chemosignal from male mice that accelerates puberty was present in the urine from about the time of puberty and throughout the normal lifespan, but declined about 1 year of age. Oestrous females released a substance in their urine that accelerates puberty in young females. This substance remained effective from first oestrus until over 1 year of age, although older females were in oestrus less frequently than younger mice. Females that are pregnant or lactating released a puberty-accelerating substance in their urine regardless of age. Production and release of the puberty-delaying chemosignal by grouped females was initiated before puberty and continued throughout the lifespan of the mouse.

[1]  L. C. Drickamer.  Effects of urine from females in oestrus on puberty in female mice. , 1986, Journal of reproduction and fertility.

[2]  L. C. Drickamer.  Effects of very small doses of urine on acceleration and delay of sexual maturation in female house mice. , 1984, Journal of reproduction and fertility.

[3]  L. C. Drickamer.  Chemosignal effects on puberty in young female mice: urine from pregnant and lactating females. , 1983, Developmental psychobiology.

[4]  F. Bronson,et al.  Deterioration of the capacity for sexual arousal in aged male mice. , 1982, Biology of reproduction.

[5]  C. Desjardins,et al.  Sexual activity of aged male mice: correlation with level of arousal, physical endurance, pathological status, and ejaculatory capacity. , 1980, Biology of reproduction.

[6]  J. E. Hoover,et al.  Effects of urine from pregnant and lactating female house mice on sexual maturation of juvenile females. , 1979, Developmental psychobiology.

[7]  C. Desjardins,et al.  Reproductive failure in aged CBF1 male mice: interrelationships between pituitary gonadotropic hormones, testicular function, and mating success. , 1977, Endocrinology.

[8]  L. C. Drickamer.  Delay of sexual maturation in female house mice by exposure to grouped females or urine from grouped females. , 1977, Journal of reproduction and fertility.

[9]  J. Vandenbergh,et al.  Pheromonally induced sexual maturation in females: regulation by the social environment of the male. , 1977, Science.

[10]  D. Colby,et al.  Regulatory effects of urinary pheromones on puberty in the mouse. , 1974, Biology of reproduction.

[11]  L. C. Drickamer,et al.  Social and dietary factors in the sexual maturation of female mice. , 1972, Journal of reproduction and fertility.

[12]  R. Berry,et al.  Life and death in an island population of the house mouse. , 1971, Experimental gerontology.

[13]  J. Vandenbergh.  Male odor accelerates female sexual maturation in mice. , 1969, Endocrinology.

[14]  L. C. Drickamer,et al.  Female mouse maturation: effects of excreted and bladder urine from juvenile and adult males. , 1978, Developmental psychobiology.

[15]  E. Hafez.  Aging and reproductive physiology , 1976 .

[16]  R. Rugh,et al.  The mouse; its reproduction and development , 1968 .