A heart failure diagnosis model based on support vector machine

To help clinicians diagnose Heart failure (HF) at the early stage, this study proposes a scoring model based on support vector machine (SVM). Missing data in clinic are imputed by employing Bayesian principal component analysis. According to the evaluation of cardiac dysfunction, samples are classified into three groups: the healthy group (without cardiac dysfunction), the HF-prone group (in asymptomatic stages of cardiac dysfunction) and the HF group (in symptomatic stages of cardiac dysfunction). The total accuracy of the model in classification is 74.4%, with accuracies of 78.79%, 87.5% and 65.85% for identifying the healthy group, the HF-prone group and the HF group, respectively. Compared with the reported results in clinical practice, the model helps to improve the accuracy of HF diagnosis,especially in screening HF patients at the early stage.

[1]  Tai-Yue Wang,et al.  One-against-one fuzzy support vector machine classifier: An approach to text categorization , 2009, Expert Syst. Appl..

[2]  E. Balas,et al.  Improving clinical practice using clinical decision support systems: a systematic review of trials to identify features critical to success , 2005, BMJ : British Medical Journal.

[3]  B. Reiser,et al.  Estimation of the Youden Index and its Associated Cutoff Point , 2005, Biometrical journal. Biometrische Zeitschrift.

[4]  H. Madeira,et al.  How patients with heart failure are managed in Portugal , 2002, European journal of heart failure.

[5]  C. Fonseca Diagnosis of heart failure in primary care , 2006, Heart Failure Reviews.

[6]  C. Lang,et al.  Non-cardiac comorbidities in chronic heart failure , 2006, Heart.

[7]  Euripidis Loukis,et al.  Support Vectors Machine-based identification of heart valve diseases using heart sounds , 2009, Comput. Methods Programs Biomed..

[8]  H. Mcdonald,et al.  Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review. , 2005, JAMA.

[9]  Roberto Cardarelli,et al.  B-type natriuretic peptide: a review of its diagnostic, prognostic, and therapeutic monitoring value in heart failure for primary care physicians. , 2003, The Journal of the American Board of Family Practice.

[10]  A. Hoes,et al.  Clinical epidemiology of heart failure , 2007, Heart.

[11]  Shin Ishii,et al.  A Bayesian missing value estimation method for gene expression profile data , 2003, Bioinform..

[12]  K. Furie,et al.  Heart disease and stroke statistics--2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. , 2008, Circulation.

[13]  J. Remes,et al.  Validity of clinical diagnosis of heart failure in primary health care. , 1991, European heart journal.

[14]  Corinna Cortes,et al.  Support-Vector Networks , 1995, Machine Learning.

[15]  A. Hungin,et al.  Barriers to accurate diagnosis and effective management of heart failure in primary care: qualitative study , 2003, BMJ : British Medical Journal.