An Objective Evaluation Method Designed for Pulsating Cardiac Phantom with 64-row MDCT

In the research of non-invasive cardiac coronary imaging with multi-detector CT (MDCT), it is necessary to use a standard cardiac phantom to perform the mass repetitive experiments. The standard phantom can help to investigate the regularity of a technology, and hence provide the instructions to clinic. In this study, an objective evaluation method of coronary stenosis rate, which can process CT images automatically, is developed with a cardiac phantom, to enhance working efficiency and to reduce subjective error. Several experiments were designed to verify the accuracy, the sensitivity and the consistency of this method. Based on the results, we found the accuracy of this objective method is within the clinical acceptable range. This method is sensitive to image quality change, and the results of the method are consistent without being affected by the environment and the operators. This proposed method can help to improve the efficiency of processing mass experimental data based on the cardiac phantom and establish a good foundation for the research on the cardiac coronary imaging with MDCT. This method is also applied to clinical images for tests and acceptable results are achieved in stenosis of low density.

[1]  Klaus Sartor,et al.  Small vessel stents for intracranial angioplasty: in vitro evaluation of in-stent stenoses using CT angiography , 2004, Neuroradiology.

[2]  姜滨,et al.  新型心脏动态体模及其在多层螺旋CT心脏扫描中的应用 , 2006 .

[3]  Xiangying Du,et al.  Effect of dose-reduced scan protocols on cardiac coronary image quality with 64-row MDCT: a cardiac phantom study. , 2008, European journal of radiology.

[4]  Matthew J Budoff,et al.  Assessment of coronary plaque morphology by contrast-enhanced computed tomographic angiography: comparison with intravascular ultrasound , 2006, Coronary artery disease.

[5]  Peter G. J. Barten,et al.  Spatiotemporal model for the contrast sensitivity of the human eye and its temporal aspects , 1993, Electronic Imaging.

[6]  R M Lang,et al.  Objective evaluation of changes in left ventricular and atrial volumes during parabolic flight using real-time three-dimensional echocardiography. , 2006, Journal of applied physiology.

[7]  Peter G. J. Barten,et al.  Physical model for the contrast sensitivity of the human eye , 1992, Electronic Imaging.

[8]  Konstantin Nikolaou,et al.  Quantification of obstructive and nonobstructive coronary lesions by 64-slice computed tomography: a comparative study with quantitative coronary angiography and intravascular ultrasound. , 2005, Journal of the American College of Cardiology.

[9]  Xiangying Du,et al.  64-MDCT coronary angiography: phantom study of effects of vascular attenuation on detection of coronary stenosis. , 2008, AJR. American journal of roentgenology.

[10]  J. Murray,et al.  ACC/AHA guidelines for coronary angiography. A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee on Coronary Angiography). Developed in collaboration with the Society for Cardiac Angiography and Interventions. , 1999, Journal of the American College of Cardiology.

[11]  Udo Hoffmann,et al.  Accuracy of 16-slice multi-detector CT to quantify the degree of coronary artery stenosis: assessment of cross-sectional and longitudinal vessel reconstructions. , 2006, European journal of radiology.

[12]  Konstantin Nikolaou,et al.  Advances in cardiac CT imaging: 64-slice scanner , 2004, The International Journal of Cardiovascular Imaging.

[13]  Werner Moshage,et al.  Noninvasive Coronary Angiography by Retrospectively ECG-Gated Multislice Spiral CT , 2000, Circulation.

[14]  Jonathan Chan,et al.  Anatomical M-mode: A novel technique for the quantitative evaluation of regional wall motion analysis during dobutamine echocardiography , 2000, The International Journal of Cardiac Imaging.

[15]  Thomas S. Spisz,et al.  Medical image processing and analysis software , 2000 .

[16]  Luigi Albani,et al.  Grayscale standard display function on LCD color monitors , 2007, SPIE Medical Imaging.