β-Catenin signaling in hepatocellular cancer: Implications in inflammation, fibrosis, and proliferation.

[1]  B. Ke,et al.  PTEN‐mediated akt/β‐Catenin/foxo1 signaling regulates innate immune responses in mouse liver ischemia/reperfusion injury , 2013, Hepatology.

[2]  J. Stauffer,et al.  Chronic inflammation, immune escape, and oncogenesis in the liver: A unique neighborhood for novel intersections , 2012, Hepatology.

[3]  H. Inui,et al.  Coordinated Action of Hypoxia-inducible Factor-1α and β-Catenin in Androgen Receptor Signaling* , 2012, The Journal of Biological Chemistry.

[4]  Sucha Singh,et al.  β-Catenin Loss in Hepatocytes Promotes Hepatocellular Cancer after Diethylnitrosamine and Phenobarbital Administration to Mice , 2012, PloS one.

[5]  H. El‐Serag,et al.  Epidemiology of viral hepatitis and hepatocellular carcinoma. , 2012, Gastroenterology.

[6]  T. Roskams,et al.  Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease , 2012, Nature Medicine.

[7]  S. Altekruse,et al.  Hepatocellular Carcinoma Confirmation, Treatment, and Survival in Surveillance, Epidemiology, and End Results Registries, 1992‐2008 , 2012, Hepatology.

[8]  V. Baud,et al.  Oncogenic β-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in mice. , 2012, The Journal of clinical investigation.

[9]  R. Dahiya,et al.  MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer. , 2012, Carcinogenesis.

[10]  Guozhong Tao,et al.  Wnt-β-catenin signaling protects against hepatic ischemia and reperfusion injury in mice. , 2011, Gastroenterology.

[11]  Satdarshan P. S. Monga,et al.  Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad. , 2011, Seminars in cancer biology.

[12]  A. Buchmann,et al.  Tumor formation in liver of conditional β-catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen. , 2011, Carcinogenesis.

[13]  Sucha Singh,et al.  Conditional β‐catenin loss in mice promotes chemical hepatocarcinogenesis: Role of oxidative stress and platelet‐derived growth factor receptor α/phosphoinositide 3‐kinase signaling , 2010, Hepatology.

[14]  C. Dai,et al.  Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine‐45 mutant β‐catenin , 2010, Hepatology.

[15]  P. Schirmacher,et al.  Signaling networks in human hepatocarcinogenesis--novel aspects and therapeutic options. , 2010, Progress in molecular biology and translational science.

[16]  M. Copetti,et al.  Changes in CpG Islands Promoter Methylation Patterns during Ductal Breast Carcinoma Progression , 2009, Cancer Epidemiology, Biomarkers & Prevention.

[17]  B. Cieply,et al.  Unique phenotype of hepatocellular cancers with exon‐3 mutations in beta‐catenin gene , 2009, Hepatology.

[18]  M. Kay,et al.  Distinct pathways of genomic progression to benign and malignant tumors of the liver , 2007, Proceedings of the National Academy of Sciences.

[19]  C. Elie,et al.  Cholestasis is a marker for hepatocellular carcinomas displaying β‐catenin mutations , 2007, The Journal of pathology.

[20]  S. Monga,et al.  WNT/β‐catenin signaling in liver health and disease , 2007 .

[21]  Derek Y. Chiang,et al.  Genomics and signaling pathways in hepatocellular carcinoma. , 2007, Seminars in liver disease.

[22]  S. Boyault,et al.  Differential effects of inactivated Axin1 and activated β-catenin mutations in human hepatocellular carcinomas , 2007, Oncogene.

[23]  S. Boyault,et al.  Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets , 2007, Hepatology.

[24]  S. Monga,et al.  WNT/beta-catenin signaling in liver health and disease. , 2007, Hepatology.

[25]  B. Cieply,et al.  Conditional deletion of beta-catenin reveals its role in liver growth and regeneration. , 2006, Gastroenterology.

[26]  Ronald A. DePinho,et al.  Hepatocellular carcinoma pathogenesis: from genes to environment , 2006, Nature Reviews Cancer.

[27]  D. Rickman,et al.  Apc tumor suppressor gene is the "zonation-keeper" of mouse liver. , 2006, Developmental cell.

[28]  Yukako Yagi,et al.  Primary histologic diagnosis using automated whole slide imaging: a validation study , 2006, BMC clinical pathology.

[29]  J. Zucman‐Rossi,et al.  Genotype–phenotype correlation in hepatocellular adenoma: New classification and relationship with HCC , 2006, Hepatology.

[30]  J. Ferlay,et al.  Global Cancer Statistics, 2002 , 2005, CA: a cancer journal for clinicians.

[31]  M. Giovannini,et al.  Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[32]  S. Friedman,et al.  Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes. , 2004, Gastroenterology.

[33]  Kazuo Suzuki,et al.  Identification of the leukocyte cell‐derived chemotaxin 2 as a direct target gene of β‐catenin in the liver , 2004, Hepatology.

[34]  S. Thorgeirsson,et al.  Thioacetamide-induced hepatic fibrosis in transforming growth factor beta-1 transgenic mice , 2004, European journal of gastroenterology & hepatology.

[35]  M. Taketo,et al.  Hepatocarcinogenesis in Mice with β-Catenin and Ha-Ras Gene Mutations , 2004, Cancer Research.

[36]  M. Taketo,et al.  Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations. , 2004, Cancer research.

[37]  Jan Kitajewski,et al.  New targets of β-catenin signaling in the liver are involved in the glutamine metabolism , 2002, Oncogene.

[38]  A. Buchmann,et al.  Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of β-catenin-mutated mouse liver tumors , 2001, Oncogene.

[39]  M. Buendia,et al.  Nuclear accumulation of mutated beta-catenin in hepatocellular carcinoma is associated with increased cell proliferation. , 1999, The American journal of pathology.

[40]  Jan Bayer,et al.  Beta-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity , 1999, Oncogene.

[41]  A. Jemal,et al.  Global cancer statistics , 2011, CA: a cancer journal for clinicians.

[42]  R. Gebhardt,et al.  Changes in distribution and activity of glutamine synthetase in carbon tetrachloride‐induced cirrhosis in the rat: Potential role in hyperammonemia , 1994, Hepatology.