Skin integrity testing and monitoring of in vitro tape stripping by capacitance‐based sensor imaging

Despite the frequent use of porcine ear skin for tape‐stripping experiments, the peculiarities of this skin type have not been characterised in detail yet. Thus, different techniques were employed to investigate the skin surface structure of porcine ear skin and the changes in barrier function during in vitro tape stripping. To this end, the potential of capacitance‐based skin hydration imaging as a means of skin quality control was investigated for the first time.

[1]  J. Lademann,et al.  Comparison of Transepidermal Water Loss and Laser Scanning Microscopy Measurements to Assess Their Value in the Characterization of Cutaneous Barrier Defects , 2011, Skin Pharmacology and Physiology.

[2]  G. Resch,et al.  Modification of the conformational skin structure by treatment with liposomal formulations and its correlation to the penetration depth of aciclovir. , 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[3]  V. Klang,et al.  Facilitating in vitro Tape Stripping: Application of Infrared Densitometry for Quantification of Porcine Stratum Corneum Proteins , 2011, Skin Pharmacology and Physiology.

[4]  R. Pons,et al.  Application of bicellar systems on skin: diffusion and molecular organization effects. , 2010, Langmuir : the ACS journal of surfaces and colloids.

[5]  G. Piérard,et al.  Characterization of the skin using capacitance imaging. , 2010 .

[6]  Min Feng,et al.  Study on the mechanisms of chitosan and its derivatives used as transdermal penetration enhancers. , 2009, International journal of pharmaceutics.

[7]  J Lademann,et al.  The tape stripping procedure--evaluation of some critical parameters. , 2009, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[8]  L. Bagatolli,et al.  Pig skin structure and transdermal delivery of liposomes: a two photon microscopy study. , 2008, Journal of controlled release : official journal of the Controlled Release Society.

[9]  V. Normand,et al.  Molecular organization of the lipid matrix in intact Stratum corneum using ATR-FTIR spectroscopy. , 2008, Biochimica et biophysica acta.

[10]  R. Voegeli,et al.  Efficient and simple quantification of stratum corneum proteins on tape strippings by infrared densitometry , 2007, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[11]  Juergen Lademann,et al.  Porcine ear skin: an in vitro model for human skin , 2007, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[12]  G. Piérard,et al.  Skin capacitance mapping of psoriasis , 2006, Journal of the European Academy of Dermatology and Venereology : JEADV.

[13]  J. Lévêque,et al.  Skin capacitance imaging, a new technique for investigating the skin surface. , 2006, European journal of dermatology : EJD.

[14]  M. Hope,et al.  The effect of bilayer and hexagonal HII phase lipid films on transepidermal water loss , 2006, Experimental dermatology.

[15]  Franck Giron,et al.  Capacitance imaging of the skin surface , 2006, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[16]  J. Lademann,et al.  Estimation of the relative stratum corneum amount removed by tape stripping , 2005, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[17]  Y. Kalia,et al.  Porcine Ear Skin as a Model for the Assessment of Transdermal Drug Delivery to Premature Neonates , 2004, Pharmaceutical Research.

[18]  J. Lévêque,et al.  What Is SkinChip®? From Silicon Image Sensor Technology to SkinChip® , 2004, Dermatology.

[19]  Bernard Querleux,et al.  SkinChip®, a new tool for investigating the skin surface in vivo , 2003, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[20]  J. Lademann,et al.  UV/VIS Absorbance Allows Rapid, Accurate, and Reproducible Mass Determination of Corneocytes Removed by Tape Stripping , 2003, Skin Pharmacology and Physiology.

[21]  R H Guy,et al.  Biophysical study of porcine ear skin in vitro and its comparison to human skin in vivo. , 2002, Journal of pharmaceutical sciences.

[22]  W. Meyer,et al.  [Skin layer thickness at the ear of the domesticated pig , with special reference to the use of the ear integument for human dermatological research]. , 2002, Berliner und Munchener tierarztliche Wochenschrift.

[23]  H.-J. Weigmann,et al.  Determination of the Horny Layer Profile by Tape Stripping in Combination with Optical Spectroscopy in the Visible Range as a Prerequisite to Quantify Percutaneous Absorption , 1999, Skin Pharmacology and Physiology.

[24]  R. Mendelsohn,et al.  FTIR Spectroscopy Studies of the Conformational Order and Phase Behavior of Ceramides , 1997 .

[25]  R H Guy,et al.  Homogeneous transport in a heterogeneous membrane: water diffusion across human stratum corneum in vivo. , 1996, Biophysical journal.

[26]  W. Meyer.  Bemerkungen zur Eignung der Schweinehaut als biologisches Modell für die Haut des Menschen , 1996, Der Hautarzt.

[27]  G. Piérard,et al.  The Skin Landscape Following Nonoptical Capacitance Imaging , 2010, American journal of clinical dermatology.

[28]  Lioudmila Tchvialeva,et al.  Skin Roughness Assessment , 2010 .

[29]  Vikas Rana,et al.  Thermotropic and spectroscopic behavior of skin: relationship with percutaneous permeation enhancement. , 2006, Current drug delivery.

[30]  Jürgen Lademann,et al.  Determination of penetration profiles of topically applied substances by means of tape stripping and optical spectroscopy: UV filter substance in sunscreens. , 2005, Journal of biomedical optics.