Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition.
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David M. Evans | D. Kiel | A. Hofman | A. Uitterlinden | J. V. van Meurs | J. Ioannidis | M. Brown | C. Christiansen | F. Rivadeneira | J. Richards | P. Lips | L. Cupples | E. McCloskey | U. Styrkarsdottir | K. Estrada | D. Mellström | D. Evans | E. Evangelou | C. Ohlsson | Ching‐Ti Liu | J. Riancho | S. Kaptoge | S. Ralston | M. Zillikens | L. Vandenput | C. Medina-Gomez | N. V. van Schoor | J. Meurs | L. Stolk | Y. Hsu | E. Ntzani | H. Pols | E. Duncan | K. Zhu | J. Lewis | Seung Hun Lee | R. Prince | G. Kim | J. Koh | D. Karasik | J. Reeve | B. Obermayer-Pietsch | M. van der Klift | M. Karlsson | David M. Evans | M. Karlsson | M. Castano-Betancourt | E. Oei | L. Oei | N. Alonso | L. Husted | B. Langdahl | Ö. Ljunggren | Lizbeth Herrera | O. Ljunggren | E. Oei | J. Hernández | J. B. Richards | Josefina Martínez | C. Valero | A. Daroszewska | Evangelos A. Evangelou | U. Styrkársdóttir | Matthew A. Brown | A. Uitterlinden | J. Hernandez | A. Hofman | M. Klift | Douglas P. Kiel | J. B. Richards | S. H. Ralston | Richard L. Prince | John P. A. Ioannidis | J. B. Richards | J. L. Hernández | Eugene V. McCloskey | K. Zhu | N. M. Schoor | A. Uitterlinden | M. Karlsson | B. Langdahl | H. Pols | E.H.G. Oei | Joshua R Lewis | Kun Zhu | Seung Hun Lee | L. A. Cupples | Matthew A. Brown | Emma L Duncan
[1] Kankana Mukherjee. Winner's Curse , 2015 .
[2] Tim D. Spector,et al. Genetics of osteoporosis from genome-wide association studies: advances and challenges , 2012, Nature Reviews Genetics.
[3] Daniel L. Koller,et al. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture , 2012, Nature Genetics.
[4] D. Kiel,et al. Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the framingham study , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[5] John P A Ioannidis,et al. What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations. , 2012, International journal of epidemiology.
[6] A. Hofman,et al. Review of radiological scoring methods of osteoporotic vertebral fractures for clinical and research settings , 2012, European Radiology.
[7] C. Cooper,et al. Osteoporosis: burden, health care provision and opportunities in the EU , 2011, Archives of osteoporosis.
[8] Eleazar Eskin,et al. Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. , 2011, American journal of human genetics.
[9] Steve D. M. Brown,et al. Genome-Wide Association Study Using Extreme Truncate Selection Identifies Novel Genes Affecting Bone Mineral Density and Fracture Risk , 2011, PLoS genetics.
[10] M. Boehnke,et al. Transferability of Type 2 Diabetes Implicated Loci in Multi-Ethnic Cohorts from Southeast Asia , 2011, PLoS genetics.
[11] B. Henderson,et al. Caution in generalizing known genetic risk markers for breast cancer across all ethnic/racial populations , 2011, European Journal of Human Genetics.
[12] A. Hofman,et al. Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium. , 2010, Osteoarthritis and cartilage.
[13] G. Abecasis,et al. MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes , 2010, Genetic epidemiology.
[14] B. Henderson,et al. Generalizability and Epidemiologic Characterization of Eleven Colorectal Cancer GWAS Hits in Multiple Populations , 2010, Cancer Epidemiology, Biomarkers & Prevention.
[15] J. Llorca,et al. Bone turnover markers in Spanish adult men The Camargo Cohort Study. , 2010, Clinica chimica acta; international journal of clinical chemistry.
[16] Sharon R Grossman,et al. Integrating common and rare genetic variation in diverse human populations , 2010, Nature.
[17] Yun Li,et al. METAL: fast and efficient meta-analysis of genomewide association scans , 2010, Bioinform..
[18] Teri A Manolio,et al. Genomewide association studies and assessment of the risk of disease. , 2010, The New England journal of medicine.
[19] L. Husted,et al. Genotypes and Haplotypes of the Estrogen Receptor Genes, but Not the Retinoblastoma-interacting Zinc Finger Protein 1 Gene, Are Associated with Osteoporosis , 2010, Calcified Tissue International.
[20] R. Prentice,et al. Correcting “winner's curse” in odds ratios from genomewide association findings for major complex human diseases , 2009, Genetic epidemiology.
[21] A. Aromaa,et al. Severity of vertebral fracture and risk of hip fracture: a nested case–control study , 2010, Osteoporosis International.
[22] J. Pasco,et al. Bone mineral density reference ranges for Australian men: Geelong Osteoporosis Study , 2010, Osteoporosis International.
[23] J. Llorca,et al. Bone turnover markers in Spanish postmenopausal women: the Camargo cohort study. , 2009, Clinica chimica acta; international journal of clinical chemistry.
[24] Peter Kraft,et al. Replication in genome-wide association studies. , 2009, Statistical science : a review journal of the Institute of Mathematical Statistics.
[25] E. Zeggini,et al. Ranking of genome-wide association scan signals by different measures. , 2009, International journal of epidemiology.
[26] Yurii S. Aulchenko,et al. Twenty bone mineral density loci identified by large-scale meta-analysis of genome-wide association studies , 2009, Nature Genetics.
[27] H. Choi,et al. The forkhead transcription factor Foxc2 stimulates osteoblast differentiation. , 2009, Biochemical and biophysical research communications.
[28] Tobias A. Knoch,et al. GRIMP: a web- and grid-based tool for high-speed analysis of large-scale genome-wide association using imputed data , 2009, Bioinform..
[29] Tomas W. Fitzgerald,et al. Genomic and Genic Deletions of the FOX Gene Cluster on 16q24.1 and Inactivating Mutations of FOXF1 Cause Alveolar Capillary Dysplasia and Other Malformations , 2009, American journal of human genetics.
[30] J. Eisman,et al. Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women. , 2009, JAMA.
[31] Monique M. B. Breteler,et al. The Rotterdam Study: 2016 objectives and design update , 2015, European Journal of Epidemiology.
[32] J. Ioannidis. Why Most Discovered True Associations Are Inflated , 2008, Epidemiology.
[33] A. Uitterlinden,et al. Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study. , 2008, Bone.
[34] M. Brown,et al. Genetic Analyses in a Sample of Individuals With High or Low BMD Shows Association With Multiple Wnt Pathway Genes , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[35] H. Shin,et al. Association of FLT3 Polymorphisms With Low BMD and Risk of Osteoporotic Fracture in Postmenopausal Women , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[36] Lester L. Peters,et al. Genome-wide association study identifies novel breast cancer susceptibility loci , 2007, Nature.
[37] Qiong Yang,et al. The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination. , 2007, American journal of epidemiology.
[38] A. Tosteson,et al. Incidence and Economic Burden of Osteoporosis‐Related Fractures in the United States, 2005–2025 , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[39] J. Riancho,et al. Identification of an aromatase haplotype that is associated with gene expression and postmenopausal osteoporosis. , 2007, The Journal of clinical endocrinology and metabolism.
[40] J. Richards,et al. Effect of selective serotonin reuptake inhibitors on the risk of fracture. , 2007, Archives of internal medicine.
[41] Jacques P. Brown,et al. Changes to Osteoporosis Prevalence According to Method of Risk Assessment , 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[42] John Brazier,et al. Clodronate Reduces the Incidence of Fractures in Community‐Dwelling Elderly Women Unselected for Osteoporosis: Results of a Double‐Blind, Placebo‐Controlled Randomized Study , 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[43] A. Uitterlinden,et al. Genetics of osteoporosis , 2007, Proceedings of the Nutrition Society.
[44] R. Hoover. The evolution of epidemiologic research: from cottage industry to "big" science. , 2007, Epidemiology.
[45] J. Riancho,et al. Adiposity, estradiol, and genetic variants of steroid-metabolizing enzymes as determinants of bone mineral density. , 2007, European journal of endocrinology.
[46] T. Werge,et al. Links between cardiovascular disease and osteoporosis in postmenopausal women: serum lipids or atherosclerosis per se? , 2006, Osteoporosis International.
[47] A. Tiran,et al. Type 2 diabetes mellitus in nursing home patients: effects on bone turnover, bone mass, and fracture risk. , 2006, The Journal of clinical endocrinology and metabolism.
[48] D. Kiel,et al. Incidence and Risk Factors for Vertebral Fracture in Women and Men: 25‐Year Follow‐Up Results From the Population‐Based Framingham Study , 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[49] D. Reich,et al. Principal components analysis corrects for stratification in genome-wide association studies , 2006, Nature Genetics.
[50] Richard L Prince,et al. Effects of calcium supplementation on clinical fracture and bone structure: results of a 5-year, double-blind, placebo-controlled trial in elderly women. , 2006, Archives of internal medicine.
[51] O. Johnell,et al. Free Testosterone is an Independent Predictor of BMD and Prevalent Fractures in Elderly Men: MrOS Sweden , 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[52] A. Uitterlinden,et al. Large-Scale Evidence for the Effect of the COLIA1 Sp1 Polymorphism on Osteoporosis Outcomes: The GENOMOS Study , 2006, PLoS medicine.
[53] Andres Metspalu,et al. An Evaluation of the Performance of Tag SNPs Derived from HapMap in a Caucasian Population , 2006, PLoS genetics.
[54] D. Gold,et al. Vertebral compression fractures in primary care: recommendations from a consensus panel. , 2005, The Journal of family practice.
[55] T. Spector,et al. The assessment of vertebral deformity: A method for use in population studies and clinical trials , 1993, Osteoporosis International.
[56] J. Reeve,et al. The European prospective osteoporosis study , 2005, Osteoporosis International.
[57] W. Shen,et al. Impact of incident vertebral fractures on health related quality of life (HRQOL) in postmenopausal women with prevalent vertebral fractures , 2005, Osteoporosis International.
[58] O Johnell,et al. A family history of fracture and fracture risk: a meta-analysis. , 2004, Bone.
[59] R. Eastell,et al. Comparison of methods for the visual identification of prevalent vertebral fracture in osteoporosis , 2004, Osteoporosis International.
[60] Toshihiro Tanaka. The International HapMap Project , 2003, Nature.
[61] J. Reeve. Determinants of the Size of Incident Vertebral Deformities in European Men and Women in the Sixth to Ninth Decades of Age: The European Prospective Osteoporosis Study (EPOS) , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[62] E. Lander,et al. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease , 2003, Nature Genetics.
[63] D. Felsenberg,et al. Defining Incident Vertebral Deformities in Population Studies: A Comparison of Morphometric Criteria , 2002, Osteoporosis International.
[64] A. Hofman,et al. The Incidence of Vertebral Fractures in Men and Women: The Rotterdam Study , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[65] J Dequeker,et al. Incidence of Vertebral Fracture in Europe: Results From the European Prospective Osteoporosis Study (EPOS) , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[66] J. Smit,et al. Attrition in the Longitudinal Aging Study Amsterdam. The effect of differential inclusion in side studies. , 2002, Journal of clinical epidemiology.
[67] M. Noda,et al. Bone Morphogenetic Protein Regulation of Forkhead/Winged Helix Transcription Factor Foxc2 (Mfh1) in a Murine Mesodermal Cell Line C1 and in Skeletal Precursor Cells , 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[68] O. Johnell,et al. A Statistical Method to Minimize Magnification Errors in Serial Vertebral Radiographs , 2001, Osteoporosis International.
[69] J. Pasco,et al. Prevalence of osteoporosis in Australian women: Geelong Osteoporosis Study. , 2000, Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry.
[70] C. Cooper,et al. Health‐Related Quality of Life in Postmenopausal Women With Low BMD With or Without Prevalent Vertebral Fractures , 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[71] J. Cauley,et al. Prevalent Vertebral Deformities Predict Mortality and Hospitalization in Older Women with Low Bone Mass , 2000, Journal of the American Geriatrics Society.
[72] A. Tenenhouse,et al. Estimation of the Prevalence of Low Bone Density in Canadian Women and Men Using a Population-Specific DXA Reference Standard: The Canadian Multicentre Osteoporosis Study (CaMos) , 2000, Osteoporosis International.
[73] A. Silman,et al. Validity of Self-Report of Fractures: Results from a Prospective Study in Men and Women Across Europe , 2000, Osteoporosis International.
[74] J Pearson,et al. Prevalent Vertebral Deformities Predict Hip Fractures and New Vertebral Deformities but Not Wrist Fractures , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[75] L. Mosekilde,et al. The Danish Osteoporosis Prevention Study (DOPS): project design and inclusion of 2000 normal perimenopausal women. , 1999, Maturitas.
[76] C. Cooper,et al. Vertebral Fractures Predict Subsequent Fractures , 1999, Osteoporosis International.
[77] S. Cummings,et al. The Association of Radiographically Detected Vertebral Fractures with Back Pain and Function: A Prospective Study , 1998, Annals of Internal Medicine.
[78] P. Ross,et al. Clinical consequences of vertebral fractures. , 1997, The American journal of medicine.
[79] B. Hogan,et al. The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo. , 1997, Genes & development.
[80] A. Hofman,et al. Vertebral Deformities and Functional Impairment in Men and Women , 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[81] A. Silman,et al. The prevalence of vertebral deformity in European men and women: The european vertebral osteoporosis study , 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[82] D. Gold. The clinical impact of vertebral fractures: quality of life in women with osteoporosis. , 1996, Bone.
[83] M. Nevitt,et al. Vertebral fracture assessment using a semiquantitative technique , 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[84] P. Allhoff,et al. The Framingham Offspring Study , 1991 .
[85] W. Kannel,et al. An investigation of coronary heart disease in families. The Framingham offspring study. , 1979, American journal of epidemiology.
[86] T. Dawber,et al. Epidemiological approaches to heart disease: the Framingham Study. , 1951, American journal of public health and the nation's health.