Progress in Medicine: Experts Take Stock

In the year-end editorial, the PLOS Medicine editors ask 11 researchers and clinicians about the most relevant challenges, promising research, and important initiatives in their fields as we head into 2016.

[1]  S. Yusuf,et al.  Availability and affordability of cardiovascular disease medicines and their effect on use in high-income, middle-income, and low-income countries: an analysis of the PURE study data , 2016, The Lancet.

[2]  D. Safer,et al.  Antipsychotic prescribing for behavioral disorders in US youth: physician specialty, insurance coverage, and complex regimens , 2016, Pharmacoepidemiology and drug safety.

[3]  H. Welch,et al.  South Korea's Thyroid-Cancer "Epidemic"--Turning the Tide. , 2015, The New England journal of medicine.

[4]  J. Hemingway.  Malaria: Fifteen years of interventions , 2015, Nature.

[5]  U. Dalrymple,et al.  The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015 , 2015, Nature.

[6]  R. Maude,et al.  Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker , 2015, The Lancet. Infectious diseases.

[7]  J. Elmore,et al.  Diagnostic concordance among pathologists interpreting breast biopsy specimens. , 2015, JAMA.

[8]  W. Rogers,et al.  The challenge of overdiagnosis begins with its definition , 2015, BMJ : British Medical Journal.

[9]  Bernadette A. Thomas,et al.  Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 , 2015, The Lancet.

[10]  D. Kwiatkowski,et al.  Spread of artemisinin resistance in Plasmodium falciparum malaria. , 2014, The New England journal of medicine.

[11]  L. Newman,et al.  The Cost and Cost-Effectiveness of Scaling up Screening and Treatment of Syphilis in Pregnancy: A Model , 2014, PloS one.

[12]  Janet B W Williams,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[13]  L. Say,et al.  Global Estimates of Syphilis in Pregnancy and Associated Adverse Outcomes: Analysis of Multinational Antenatal Surveillance Data , 2013, PLoS medicine.

[14]  G. Reed,et al.  Toward ICD-11: Improving the Clinical Utility of WHO's International Classification of Mental Disorders , 2010 .

[15]  S. Fowler,et al.  Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. , 2002, The New England journal of medicine.

[16]  C. Dolea,et al.  World Health Organization , 1949, International Organization.

[17]  Jim Y. Kim.  WHO VALIDATES ELIMINATION OF MOTHER-TO-CHILD TRANSMISSION OF HIV AND SYPHILIS IN CUBA. , 2015, Saudi medical journal.

[18]  Atta Abbas,et al.  DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS, FIFTH EDITION , 2013 .

[19]  Toshihiro Mita,et al.  Evolution of Plasmodium falciparum drug resistance: implications for the development and containment of artemisinin resistance. , 2012, Japanese journal of infectious diseases.

[20]  U. Unicef,et al.  Global HIV/AIDS response: epidemic update and health sector progress towards universal access: progress report 2011. , 2011 .

[21]  Alan D. Lopez,et al.  The Global Burden of Disease Study , 2003 .