Inflammatory myofibroblastic tumor of the appendix arising after treatment of gastric cancer: a case report and review of the literature

Inflammatory myofibroblastic tumor (IMT) is a rare soft tissue neoplasm of uncertain malignant potential and unclear etiology. IMT involving the appendix is very rare. Herein, we report a case of IMT of the appendix in a gastric cancer patient who was treated with radical gastrectomy and adjuvant systemic chemotherapy. Rare cases of IMT associated with preceding events have been described in other organs/sites, but not in the appendix. A previous intra‐abdominal operation for gastric cancer may contribute to the development of IMT in the appendix as seen in the present patient. To our knowledge, this is the first case of appendiceal IMT arising after a previous operation.

[1]  A. Rastogi,et al.  Inflammatory myofibroblastic tumor appendix with concomitant mucosal dysplasia, simulating pseudomyxoma on preoperative aspiration cytology. , 2012, Journal of cancer research and therapeutics.

[2]  G. Magro,et al.  Post-traumatic inflammatory pseudotumor of the breast with atypical morphological features: A potential diagnostic pitfall. Report of a case and a critical review of the literature. , 2011, Pathology, research and practice.

[3]  M. Uludağ,et al.  Inflammatory Pseudo-Tumour of the Appendix and Acute Appendicitis: a Case Report , 2008, Acta chirurgica Belgica.

[4]  T. M. Yelbuz,et al.  Lower abdominal inflammatory myofibroblastic tumor -an unusual presentation- a case report and brief literature review , 2007, European Journal of Pediatrics.

[5]  M. Ippoliti,et al.  Intra-abdominal inflammatory myofibroblastic pseudotumor: case report and review of the literature. , 2005, Il Giornale di chirurgia.

[6]  D. Dijoux,et al.  Abdominal inflammatory myofibroblastic tumors in children: report of an appendiceal case and review of the literature. , 1996, Journal of pediatric surgery.

[7]  Louis P. Dehner,et al.  Extrapulmonary Inflammatory Myofibroblastic Tumor (Inflammatory Pseudotumor) A Clinicopathologic and Immunohistochemical Study of 84 Cases , 1995, The American journal of surgical pathology.

[8]  G. Vujanić,et al.  Aggressive inflammatory pseudotumor of the abdomen 9 years after therapy for wilms tumor. A complication, coincidence, or association? , 1992, Cancer.

[9]  M. Mimouni,et al.  Inflammatory pseudotumor in childhood. A diagnostic and therapeutic dilemma. , 1991, Archives of surgery.

[10]  F. Mertens,et al.  World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone , 2002 .

[11]  M. Newbould,et al.  Inflammatory pseudotumor of the liver masquerading as a metastasis in a child treated for nephroblastoma. , 1992, Medical and Pediatric Oncology.