Kanglexin, a novel anthraquinone compound, protects against myocardial ischemic injury in mice by suppressing NLRP3 and pyroptosis

[1]  Z. Du,et al.  Aloe-Emodin Attenuates Myocardial Infarction and Apoptosis Via Up-Regulating MiR-133 Expression. , 2019, Pharmacological research.

[2]  J. Downey,et al.  Innate immunity as a target for acute cardioprotection. , 2019, Cardiovascular research.

[3]  Yu-ping Yang,et al.  Emodin Attenuates Lipopolysaccharide-Induced Injury via Down-Regulation of miR-223 in H9c2 Cells. , 2019, International heart journal.

[4]  Jiancheng Huang,et al.  Emodin protects H9c2 cells against hypoxia‐induced injury via regulation of miR‐26a/survivin and the JAK1/STAT3 pathway , 2019, Journal of cellular biochemistry.

[5]  Zhihong Liu,et al.  Rhein protects the myocardiac cells against hypoxia/reoxygention-induced injury by suppressing GSK3β activity. , 2018, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[6]  K. Cianflone,et al.  Trimetazidine Attenuates Cardiac Dysfunction in Endotoxemia and Sepsis by Promoting Neutrophil Migration , 2018, Front. Immunol..

[7]  J. Sun,et al.  MiR-223 promotes cardiomyocyte apoptosis by inhibiting Foxo3a expression. , 2018, European review for medical and pharmacological sciences.

[8]  T. Yi,et al.  NF-κB-Gasdermin D (GSDMD) Axis Couples Oxidative Stress and NACHT, LRR and PYD Domains-Containing Protein 3 (NLRP3) Inflammasome-Mediated Cardiomyocyte Pyroptosis Following Myocardial Infarction , 2018, Medical science monitor : international medical journal of experimental and clinical research.

[9]  J. Downey,et al.  Caspase-1 inhibition by VX-765 administered at reperfusion in P2Y12 receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function , 2018, Basic Research in Cardiology.

[10]  J. Ge,et al.  Liraglutide attenuates NLRP3 inflammasome-dependent pyroptosis via regulating SIRT1/NOX4/ROS pathway in H9c2 cells. , 2018, Biochemical and biophysical research communications.

[11]  A. Abbate,et al.  The NLRP3 inflammasome in acute myocardial infarction , 2018, Nature Reviews Cardiology.

[12]  Chaoqian Xu,et al.  LncRNA ZFAS1 as a SERCA2a Inhibitor to Cause Intracellular Ca2+ Overload and Contractile Dysfunction in a Mouse Model of Myocardial Infarction , 2018, Circulation research.

[13]  C. Esmon,et al.  Cytoprotective activated protein C averts Nlrp3 inflammasome-induced ischemia-reperfusion injury via mTORC1 inhibition. , 2017, Blood.

[14]  Wenliang Zhu,et al.  Aloe-Emodin Relieves High-Fat Diet Induced QT Prolongation via MiR-1 Inhibition and IK1 Up-Regulation in Rats , 2017, Cellular Physiology and Biochemistry.

[15]  M. Dutot,et al.  25-Hydroxycholesterol induces both P2X7-dependent pyroptosis and caspase-dependent apoptosis in human skin model: New insights into degenerative pathways. , 2017, Chemistry and physics of lipids.

[16]  BullónPedro,et al.  Could NLRP3–inflammasome be a cardiovascular risk biomarker in acute myocardial infarction patients? , 2017 .

[17]  Mei Xue,et al.  P2X7 receptor inhibition attenuated sympathetic nerve sprouting after myocardial infarction via the NLRP3/IL‐1β pathway , 2017, Journal of cellular and molecular medicine.

[18]  Wenqing Gao,et al.  Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death. , 2017, Trends in biochemical sciences.

[19]  Jian-chun Luo,et al.  Dihydromyricetin Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Mice , 2017, BioMed research international.

[20]  G. Pasterkamp,et al.  The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction , 2016, European heart journal.

[21]  Meryem Temiz-Reşitoğlu,et al.  Inhibition of NLRP3 Inflammasome Prevents LPS-Induced Inflammatory Hyperalgesia in Mice: Contribution of NF-κB, Caspase-1/11, ASC, NOX, and NOS Isoforms , 2016, Inflammation.

[22]  H. Zhang,et al.  PEDF Inhibits the Activation of NLRP3 Inflammasome in Hypoxia Cardiomyocytes through PEDF Receptor/Phospholipase A2 , 2016, International journal of molecular sciences.

[23]  J. Lieberman,et al.  Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores , 2016, Nature.

[24]  S. Carbone,et al.  Inhibition of the NLRP3 inflammasome limits the inflammatory injury following myocardial ischemia-reperfusion in the mouse. , 2016, International journal of cardiology.

[25]  M. Schultz,et al.  Nlrp3 plays no role in acute cardiac infarction due to low cardiac expression. , 2014, International journal of cardiology.

[26]  Masafumi Takahashi.  NLRP3 inflammasome as a novel player in myocardial infarction. , 2014, International heart journal.

[27]  J. Spertus,et al.  Beyond medication prescription as performance measures: optimal secondary prevention medication dosing after acute myocardial infarction. , 2013, Journal of the American College of Cardiology.

[28]  A. Abbate,et al.  Role of NLRP3 (cryopyrin) in acute myocardial infarction. , 2013, Cardiovascular research.

[29]  D. Atar,et al.  ESC Guidelines for the Management of Acute Myocardial Infarction in Patients Presenting With ST-Segment Elevation , 2013 .

[30]  R A Knight,et al.  Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 , 2011, Cell Death and Differentiation.

[31]  K. Mahaffey,et al.  Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology ( ESC ) , 2012 .

[32]  N. Voelkel,et al.  The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse , 2011, Proceedings of the National Academy of Sciences.

[33]  Meng Chen,et al.  Salvianolic acid B and Tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways , 2011, Therapeutic advances in cardiovascular disease.

[34]  B. V. Van Tassell,et al.  Interleukin‐1β modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse , 2010, European journal of heart failure.

[35]  A. J. Valente,et al.  Neutralization of Interleukin-18 Ameliorates Ischemia/Reperfusion-induced Myocardial Injury* , 2009, Journal of Biological Chemistry.

[36]  B. Cookson,et al.  Pyroptosis: host cell death and inflammation , 2009, Nature Reviews Microbiology.

[37]  D. Srivastava,et al.  Thymosin β4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair , 2004, Nature.

[38]  T. Litovitz,et al.  Electrocardiographic changes associated with beta-blocker toxicity. , 2002, Annals of emergency medicine.

[39]  A. Deten,et al.  Cardiac cytokine expression is upregulated in the acute phase after myocardial infarction. Experimental studies in rats. , 2002, Cardiovascular research.

[40]  J. Love.  Electrocardiographic Changes Associated with Beta Blocker Intoxication , 2002 .

[41]  J. Howell,et al.  Electrocardiographic changes associated with beta-blocker toxicity. , 2002, Annals of emergency medicine.

[42]  J. Cohn,et al.  Cardiac remodeling--concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling. , 2000, Journal of the American College of Cardiology.

[43]  M. Boggild.  Intracerebral haemorrhage after dermal nitrate application. , 1992, BMJ.