Oral allergy syndrome amongst young Mexicans: prevalence and associated factors

Doi 10.23822/EurAnnACI.1764-1489.59 Summary Background. Oral allergy syndrome (OAS) is the most common food allergy manifestation amongst adults. However, population studies aimed at estimating its prevalence and associated factors are scarce in Mexico. Objectives. To establish the prevalence of OAS in a sample of university students and to describe their clinical characteristics and its associated factors. Methods. From a sample group made up of 25,269 university students, the data corresponding to 1,200 students aged 18 to 25 was analyzed with a crosssectional approach. A structured questionnaire was used to identify OAS, its symptoms and related foods, and the personal history of atopic diseases. The associations between variables were calculated through logistical regression analysis. Results. The prevalence of OAS was 3.4%, with a 95% confidence interval (95% CI) of 2.5 to 4.6. The main oral symptoms reported were lip pruritus, edema and the sensation of pharyngeal oppression. Among the extra-oral complaints were: reddish coloration of the skin, body pruritus, abdominal pain, and abdominal bloating. The foods that were most frequently associated with OAS were fruits (68.5%), vegetables (22.0%) and seafood (19.3%). Through multivariate analyses, allergy to pollen and latex were found to be associated with OAS, OR 3.29; 95%: CI 1.53 to 7.10 and OR 5.53; 95% CI: 1.08 to 28.2, respectively. Conclusions. Notably, the prevalence of OAS varies according to the geographic area. Personal histories of allergy to pollen or latex were the main factors linked to OAS.

[1]  C. Cingi,et al.  Oral Allergy Syndrome , 2018, American journal of rhinology & allergy.

[2]  M. Flores-Merino,et al.  Self-reported prevalence and risk factors associated with food hypersensitivity in Mexican young adults. , 2016, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

[3]  L. Bojić,et al.  Prevalence and risk factors for developing oral allergy syndrome in adult patients with seasonal allergic rhinitis. , 2015, Acta clinica Croatica.

[4]  M. Bedolla-Barajas,et al.  Food Hypersensitivity in Mexican Adults at 18 to 50 Years of Age: A Questionnaire Survey , 2014, Allergy, asthma & immunology research.

[5]  N. Segura-Méndez,et al.  [Oral allergy syndrome in adults of a third level hospital]. , 2014, Revista alergia Mexico.

[6]  M. Bedolla-Barajas,et al.  Frequency and clinical features of the oral allergy syndrome in Mexican adults with nasal pollinosis. , 2013, Revista alergia Mexico.

[7]  C. Colak,et al.  Risk factors for oral allergy syndrome in patients with seasonal allergic rhinitis. , 2011, Medicina oral, patologia oral y cirugia bucal.

[8]  C. Katelaris Food allergy and oral allergy or pollen-food syndrome , 2010, Current opinion in allergy and clinical immunology.

[9]  S. Durham,et al.  Prevalence of pollen-related Oral Allergy Syndrome (OAS) in a UK population , 2010 .

[10]  J. López-López,et al.  Sensibilización a pólenes de la familia Oleaceae en un grupo de pacientes de la Ciudad de México , 2009 .

[11]  J. Marrugo,et al.  Prevalence of self-reported food allergy in Cartagena (Colombia) population. , 2008, Allergologia et immunopathologia.

[12]  Z. Ikezawa,et al.  Oral allergy syndrome due to plant-derived foods: a clinical review of 63 patients over a period of 6 years , 2007, Arerugi = [Allergy].

[13]  S. Vieths,et al.  The oral allergy syndrome: improved diagnostic and treatment methods , 2005, Current opinion in allergy and clinical immunology.

[14]  H. Falcão,et al.  Food hypersensitivity in Portuguese adults , 2004, European Journal of Clinical Nutrition.

[15]  U. Bengtsson,et al.  Self-reported food hypersensitivity in Sweden, Denmark, Estonia, Lithuania, and Russia. , 2004, Journal of investigational allergology & clinical immunology.

[16]  A. Nowak‐Wegrzyn,et al.  A survey on the management of pollen-food allergy syndrome in allergy practices. , 2003, The Journal of allergy and clinical immunology.

[17]  S. Wagner,et al.  The latex-fruit syndrome. , 2002, Biochemical Society transactions.

[18]  C. B. Guerra Síndrome látex-frutas , 2002 .

[19]  S. Fukuda,et al.  Springtime pollinosis and oral allergy syndrome in Sapporo. , 2001, Auris, nasus, larynx.

[20]  J. Cuesta-Herranz,et al.  Allergy to plant‐derived fresh foods in a birch‐ and ragweed‐free area , 2000, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[21]  R. Asero,et al.  Detection of prognostic factors for oral allergy syndrome in patients with birch pollen hypersensitivity. , 1996, The Journal of allergy and clinical immunology.

[22]  A. Bircher,et al.  IgE to food allergens are highly prevalent in patients allergic to pollens, with and without symptoms of food allergy , 1994, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[23]  D. Kemeny,et al.  Oral allergy syndrome (OAS): symptoms of IgE‐mediated hypersensitivity to foods , 1987, Clinical allergy.