Malignant struma ovarii: Report of two cases and selected review of the literature

Malignant struma ovarii is an extremely rare tumor. Two new cases are described and current perspectives provided. Both cases are examples of the mixed form of the disease, and both were treated by surgery alone. One patient underwent total hysterectomy and bilateral salpingo‐oophorectomy; the other had unilateral salpingo‐oophorectomy. Both patients remained free of recurrent disease at 20 and 33 months from diagnosis. The controversies relating to therapy and diagnosis are discussed in detail.

[1]  N. G. Rosenblum,et al.  Malignant struma ovarli , 1989 .

[2]  Speers Wc,et al.  Malignant struma ovarii. A case report and literature review. , 1983 .

[3]  F. Pardo‐Mindán,et al.  Malignant struma ovarii: Light and electron microscopic study , 1983, Cancer.

[4]  S. Robboy,et al.  Strumal carcinoid of the ovary: An analysis of 50 cases of a distinctive tumor composed of thyroid tissue and carcinoid , 1980, Cancer.

[5]  A. Tashjian,et al.  Immunocytochemical localization of calcitonin‐producing cells in a strumal carcinoid with amyloid stroma , 1979, Cancer.

[6]  A. Blaustein Calcitonin secreting struma-carcinoid tumor of the ovary. , 1979, Human pathology.

[7]  G. Ueda,et al.  Strumal carcinoid of the ovary: histological, ultrastructural, and immunohistological studies with anti-human thyroglobulin. , 1978, Gynecologic oncology.

[8]  J. V. Johannessen,et al.  The fine structure of human thyroid cancer. , 1978, Human pathology.

[9]  P. Hasleton,et al.  Benign and malignant struma ovarii. , 1978, Archives of pathology & laboratory medicine.

[10]  L. Valenta,et al.  Ultrastructure and biochemistry of thyroid carcinoma , 1977, Cancer.

[11]  N. Janovski,et al.  Ovarian tumors. Tumors and tumor-like conditions of the ovaries, fallopian tubes and ligaments of the uterus. , 1973, Major problems in obstetrics and gynecology.

[12]  D. L. Hoffman,et al.  Struma ovarii--ascitic, hyperthyroid, and asymptomatic syndromes. , 1970, Annals of internal medicine.

[13]  H. W. Mayberger Adenocarcinoma of Thyroid Origin in a Benign Cystic Teratoma , 1959 .

[14]  E. Novak Gynecologic and obstetric pathology, with clinical and endocrine relations , 1947 .

[15]  F. Smith Pathology and physiology of struma ovarii. , 1946, Archives of surgery.

[16]  L. Bakay,et al.  CEREBRAL MERASTASES OF OVARIAN STRUMA , 1946 .