Increasing rates of cardiac device infections among Medicare beneficiaries: 1990-1999.

Abstract Background Although cardiac devices have been found to reduce symptoms and mortality rates in appropriate patient populations, the implications of certain important risks, such as infection, are incompletely understood. The purpose of this study was to use a large population-based database to define the population that is at risk for cardiac device infections, determine the prevalence of device infections, and study changes in the rates of cardiac device implantation and infection in the past decade. Methods Patients with cardiac device implantations and infections were identified with claims files from the Health Care Finance Administration for Medicare beneficiaries from January 1, 1990, through December 31, 1999. Rates of implantation of cardiac devices were determined. Time trend analyses were performed to determine the significance of the observed change in rates. Results Cardiac device implantation rates increased from 3.26 implantations per 1000 beneficiaries in 1990 to 4.64 implantations per 1000 beneficiaries in 1999, which represents an increase of 42% in 10 years ( P for trend P for trend Conclusions During the previous decade, there was a significant increase in both cardiac device implantations and infections in elderly patients, although the increase in the rates of device infections was substantially higher. Additional studies are needed to better understand the relationship and timing between cardiac device implantation and infection.

[1]  V L Gott,et al.  Termination of malignant ventricular arrhythmias with an implanted automatic defibrillator in human beings. , 1980, The New England journal of medicine.

[2]  David Longworth,et al.  Diagnosis and Management of Infections Involving Implantable Electrophysiologic Cardiac Devices , 2000, Annals of Internal Medicine.

[3]  A. Moss,et al.  Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. Multicenter Automatic Defibrillator Implantation Trial Investigators. , 1996, The New England journal of medicine.

[4]  K. McDonald,et al.  Utilization and outcomes of the implantable cardioverter defibrillator, 1987 to 1995. , 2002, American heart journal.

[5]  M C Oz,et al.  Long-term use of a left ventricular assist device for end-stage heart failure. , 2001, The New England journal of medicine.

[6]  M C Oz,et al.  Implantable left ventricular assist devices. , 1998, The New England journal of medicine.

[7]  E. DeLong,et al.  Discordance of Databases Designed for Claims Payment versus Clinical Information Systems: Implications for Outcomes Research , 1993, Annals of Internal Medicine.

[8]  W G Henderson,et al.  Outcomes 15 years after valve replacement with a mechanical versus a bioprosthetic valve: final report of the Veterans Affairs randomized trial. , 2000, Journal of the American College of Cardiology.

[9]  F. Grover,et al.  Determinants of the occurrence of and survival from prosthetic valve endocarditis. Experience of the Veterans Affairs Cooperative Study on Valvular Heart Disease. , 1994, The Journal of thoracic and cardiovascular surgery.

[10]  M. Vanantwerp,et al.  The Artificial Heart Program: Current Status and History , 1991 .

[11]  F. Grover,et al.  Determinants of the occurrence of and survival from prosthetic valve endocarditis , 1994 .

[12]  Vance G. Fowler,et al.  Staphylococcus aureus Bacteremia in Patients With Permanent Pacemakers or Implantable Cardioverter-Defibrillators , 2001, Circulation.

[13]  E. Blackstone,et al.  Death and other time-related events after valve replacement. , 1985, Circulation.

[14]  J. Oss,et al.  PROPHYLACTIC IMPLANTATION OF A DEFIBRILLATOR IN PATIENTS WITH MYOCARDIAL INFARCTION AND REDUCED EJECTION FRACTION , 2002 .

[15]  C. Cobbs,et al.  Prosthetic valve endocarditis. , 1984, Circulation.

[16]  D Lacroix,et al.  Systemic infection related to endocarditis on pacemaker leads: clinical presentation and management. , 1997, Circulation.

[17]  H Le Breton,et al.  Pacemaker lead infection: echocardiographic features, management, and outcome , 1999, Heart.

[18]  J. Daubert,et al.  Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay. , 2001, The New England journal of medicine.

[19]  E. Wong,et al.  Prosthetic valve endocarditis: superiority of surgical valve replacement versus medical therapy only. , 1994, The Annals of thoracic surgery.

[20]  H. Trappe,et al.  Infections after cardioverter-defibrillator implantation: observations in 335 patients over 10 years. , 1995, British heart journal.

[21]  A. Gage,et al.  Correction of complete heart block by a self-contained and subcutaneously implanted pacemaker. Clinical experience with 15 patients. , 1961, The Journal of thoracic and cardiovascular surgery.

[22]  K. Lee,et al.  A randomized study of the prevention of sudden death in patients with coronary artery disease. Multicenter Unsustained Tachycardia Trial Investigators. , 1999, The New England journal of medicine.

[23]  H. Soroff,et al.  Partial and complete prostheses in aortic insufficiency. , 1960, The Journal of thoracic and cardiovascular surgery.

[24]  A. Pavie,et al.  Pacemaker infective endocarditis. , 1998, The American journal of cardiology.

[25]  R. Morris,et al.  Management of infected implantable cardiac defibrillators. , 1997, The Annals of thoracic surgery.