Cytochrome P450 in Rodents

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[8]  S. Imaoka,et al.  Changes in the amount of cytochrome P450s in rat hepatic microsomes with starvation. , 1990, Archives of biochemistry and biophysics.

[9]  S. Imaoka,et al.  Characterization of three cytochrome P450s purified from renal microsomes of untreated male rats and comparison with human renal cytochrome P450. , 1990, Archives of biochemistry and biophysics.

[10]  J. Goldstein,et al.  Hormonal regulation of male-specific rat hepatic cytochrome P-450g (P-450IIC13) by androgens and the pituitary. , 1989, The Journal of biological chemistry.

[11]  M. Correia,et al.  Purification and characterization of a mouse liver cytochrome P-450 induced by cannabidiol. , 1989, Molecular pharmacology.

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[13]  R. Kato,et al.  Cytochrome P450 in livers of diabetic rats: regulation by growth hormone and insulin. , 1989, Archives of biochemistry and biophysics.

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[15]  J. Schenkman,et al.  Further characterization of RLM2 and comparison with a related form of cytochrome P-450, RLM2b. , 1988, Archives of biochemistry and biophysics.

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[18]  M. Negishi,et al.  Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene. , 1988, The Journal of biological chemistry.

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[20]  J. Schenkman,et al.  Regioselective hydroxylation of prostaglandins by constitutive forms of cytochrome P-450 from rat liver: formation of a novel metabolite by a female-specific P-450. , 1988, Archives of biochemistry and biophysics.

[21]  S. Imaoka,et al.  Purification and characterization of two constitutive cytochromes P-450 (F-1 and F-2) from adult female rats: identification of P-450F-1 as the phenobarbital-inducible cytochrome P-450 in male rat liver. , 1987, Biochimica et biophysica acta.

[22]  S. Imaoka,et al.  Purification and characterization of liver microsomal cytochrome P-450 from untreated male rats. , 1987, Biochimica et biophysica acta.

[23]  J. Schenkman,et al.  Responses to insulin by two forms of rat hepatic microsomal cytochrome P-450 that undergo major (RLM6) and minor (RLM5b) elevations in diabetes. , 1987, The Journal of biological chemistry.

[24]  S. Imaoka,et al.  Purification and characterization of six cytochromes P-450 from hepatic microsomes of immature female rats. , 1987, Journal of biochemistry.

[25]  M. P. Arlotto,et al.  Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450. , 1987, Archives of biochemistry and biophysics.

[26]  P. Thomas,et al.  Regulation of cytochrome P-450j, a high-affinity N-nitrosodimethylamine demethylase, in rat hepatic microsomes. , 1987, Biochemistry.

[27]  C. Kozak,et al.  Debrisoquine 4-hydroxylase: characterization of a new P450 gene subfamily, regulation, chromosomal mapping, and molecular analysis of the DA rat polymorphism. , 1987, DNA.

[28]  F. Gonzalez,et al.  Isolation, complementary DNA sequence, and regulation of rat hepatic lauric acid omega-hydroxylase (cytochrome P-450LA omega). Identification of a new cytochrome P-450 gene family. , 1987, The Journal of biological chemistry.

[29]  M. Noshiro,et al.  Pretranslational regulation of sex-dependent testosterone hydroxylases by growth hormone in mouse liver. , 1986, The Journal of biological chemistry.

[30]  P. Thomas,et al.  Age- and sex-related expression of cytochromes p450f and P450g in rat liver. , 1986, Archives of biochemistry and biophysics.

[31]  C. Bonfils,et al.  Purification and characterization of a new form of cytochrome P-450 (LM2b) from untreated male rabbit liver microsomes. , 1986, Biochemical and biophysical research communications.

[32]  J. Casazza,et al.  Identification of ethanol-inducible P-450 isozyme 3a as the acetone and acetol monooxygenase of rabbit microsomes. , 1985, The Journal of biological chemistry.

[33]  S. Imaoka,et al.  Simultaneous purification of multiple forms of rat liver microsomal cytochrome P-450 by high-performance liquid chromatography. , 1985, Biochimica et biophysica acta.

[34]  D. Waxman,et al.  Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes. , 1985, Biochemistry.

[35]  D. Nebert,et al.  Complete cDNA and protein sequence of a pregnenolone 16 alpha-carbonitrile-induced cytochrome P-450. A representative of a new gene family. , 1985, The Journal of biological chemistry.

[36]  J. Schenkman,et al.  Purification and characterization of a new form (RLM2) of liver microsomal cytochrome P-450 from untreated rat. , 1985, The Journal of biological chemistry.

[37]  M. J. Coon,et al.  Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P-450 of rabbit liver microsomes by diverse agents: ethanol, imidazole, trichloroethylene, acetone, pyrazole, and isoniazid. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[38]  P. Thomas,et al.  Characterization of a major form of rat hepatic microsomal cytochrome P-450 induced by isoniazid. , 1985, The Journal of biological chemistry.

[39]  C. Lieber,et al.  New pathway for retinol metabolism in liver microsomes. , 1985, The Journal of biological chemistry.

[40]  P. Watkins,et al.  Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p. , 1985, Biochemistry.

[41]  M. J. Coon,et al.  Metabolism of nitrosamines by purified rabbit liver cytochrome P-450 isozymes. , 1985, Cancer research.

[42]  K. Holm,et al.  Isolation by ion-exchange high performance liquid chromatography of rabbit liver cytochrome P-450 with regioselectivity for omega-hydroxylation of prostaglandins. , 1985, The Journal of biological chemistry.

[43]  K. Griffin,et al.  Variations in hepatic progesterone 21-hydroxylase activity reflect differences in the microsomal concentration of rabbit cytochrome P-450 1. , 1985, Archives of biochemistry and biophysics.

[44]  D. Waxman Rat hepatic cytochrome P-450 isoenzyme 2c. Identification as a male-specific, developmentally induced steroid 16 alpha-hydroxylase and comparison to a female-specific cytochrome P-450 isoenzyme. , 1984, The Journal of biological chemistry.

[45]  J. Gustafsson,et al.  Purification, characterization, and pituitary regulation of the sex-specific cytochrome P-450 15 beta-hydroxylase from liver microsomes of untreated female rats. , 1984, The Journal of biological chemistry.

[46]  D. Williams,et al.  A prostaglandin omega-hydroxylase cytochrome P-450 (P-450PG-omega) purified from lungs of pregnant rabbits. , 1984, The Journal of biological chemistry.

[47]  D. Nebert,et al.  Purification and characterization of a microsomal cytochrome P-450 with high activity of coumarin 7-hydroxylase from mouse liver. , 1984, European journal of biochemistry.

[48]  M. Ingelman-Sundberg,et al.  Induction of the ethanol-inducible form of rabbit liver microsomal cytochrome P-450 by inhibitors of alcohol dehydrogenase. , 1984, Biochemical and biophysical research communications.

[49]  N. Harada,et al.  Mouse liver testosterone 16 alpha-hydroxylase (cytochrome P-450(16) alpha). Purification, regioselectivity, stereospecificity, and immunochemical characterization. , 1984, The Journal of biological chemistry.

[50]  F. Guengerich,et al.  Purification and characterization of the rat liver microsomal cytochrome P-450 involved in the 4-hydroxylation of debrisoquine, a prototype for genetic variation in oxidative drug metabolism. , 1984, Biochemistry.

[51]  M. Komori,et al.  Purification and characterization of cytochrome P-450 with high affinity for 7-alkoxycoumarins. , 1984, Journal of biochemistry.

[52]  P. Thomas,et al.  Characterization of three highly purified cytochromes P-450 from hepatic microsomes of adult male rats. , 1984, The Journal of biological chemistry.

[53]  N. Harada,et al.  Mouse liver testosterone 15 alpha-hydroxylase (cytochrome P-450(15) alpha). Purification, regioselectivity, stereospecificity, and sex-dependent expression. , 1984, The Journal of biological chemistry.

[54]  C. Walsh,et al.  Regioselectivity and stereoselectivity of androgen hydroxylations catalyzed by cytochrome P-450 isozymes purified from phenobarbital-induced rat liver. , 1983, The Journal of biological chemistry.

[55]  C. Walsh,et al.  Cytochrome P-450 isozyme 1 from phenobarbital-induced rat liver: purification, characterization, and interactions with metyrapone and cytochrome b5. , 1983, Biochemistry.

[56]  T. Kamataki,et al.  Sex difference of cytochrome P-450 in the rat: purification, characterization, and quantitation of constitutive forms of cytochrome P-450 from liver microsomes of male and female rats. , 1983, Archives of biochemistry and biophysics.

[57]  P. Thomas,et al.  Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes. , 1983, The Journal of biological chemistry.

[58]  P. Thomas,et al.  Induction of two immunochemically related rat liver cytochrome P-450 isozymes, cytochromes P-450c and P-450d, by structurally diverse xenobiotics. , 1983, The Journal of biological chemistry.

[59]  M. J. Coon,et al.  Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits. Oxidation of alcohols. , 1982, The Journal of biological chemistry.

[60]  F. Guengerich,et al.  Purification and characterization of liver microsomal cytochromes p-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or beta-naphthoflavone. , 1982, Biochemistry.

[61]  M. Boyd,et al.  The relationship between the catalytic activities of rabbit pulmonary cytochrome P-450 isozymes and the lung-specific toxicity of the furan derivative, 4-ipomeanol. , 1982, Molecular pharmacology.

[62]  P. Thomas,et al.  Purification and characterization of a minor form of hepatic microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls☆ , 1982 .

[63]  Y. Fujii‐Kuriyama,et al.  Primary structure of a cytochrome P-450: coding nucleotide sequence of phenobarbital-inducible cytochrome P-450 cDNA from rat liver. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[64]  N. Elshourbagy,et al.  Immunochemical evidence for induction of a common form of hepatic cytochrome P-450 in rats treated with pregnenolone-16 alpha-carbonitrile or other steroidal or non-steroidal agents. , 1982, Molecular pharmacology.

[65]  J. Schenkman,et al.  Purification and characterization of two constitutive forms of rat liver microsomal cytochrome P-450. , 1982, The Journal of biological chemistry.

[66]  M. J. Coon,et al.  Properties of electrophoretically homogeneous constitutive forms of liver microsomal cytochrome P-450. , 1981, The Journal of biological chemistry.

[67]  P. Thomas,et al.  Regulation of three forms of cytochrome P-450 and epoxide hydrolase in rat liver microsomes. Effects of age, sex, and induction. , 1981, The Journal of biological chemistry.

[68]  Y. Funae,et al.  High-performance liquid chromatography technique for resolving multiple forms of hepatic membrane-bound cytochrome P-450. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[69]  N. Elshourbagy,et al.  Separation, purification, and characterization of a novel form of hepatic cytochrome P-450 from rats treated with pregnenolone-16 alpha-carbonitrile. , 1980, The Journal of biological chemistry.

[70]  E. Johnson,et al.  Isolation and characterization of a constitutive form of rabbit liver microsomal cytochrome P-450. , 1980, The Journal of biological chemistry.

[71]  D. Nebert,et al.  Structural gene products of the Ah locus. Genetic and immunochemical evidence for two forms of mouse liver cytochrome P-450 induced by 3-methylcholanthrene. , 1979, The Journal of biological chemistry.

[72]  C. Wolf,et al.  The rabbit pulmonary monooxygenase system. Catalytic differences between two purified forms of cytochrome P-450 in the metabolism of benzo(a)pyrene. , 1979, The Journal of biological chemistry.

[73]  P. Thomas,et al.  Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene. , 1979, The Journal of biological chemistry.

[74]  U. Muller-eberhard,et al.  Identification of the major cytochrome P-450 form transplacentally induced in neonatal rabbits by 3,3,7,8-tetrachlorodibenzo-p-dioxin. , 1978, The Journal of biological chemistry.

[75]  A. Y. Lu,et al.  Separation, purification, and properties of multiple forms of cytochrome P-450 from the liver microsomes of phenobarbital-treated mice. , 1976, The Journal of biological chemistry.

[76]  M. J. Coon,et al.  Cytochrome P-450 purified to apparent homogeneity from phenobarbital-induced rabbit liver microsomes: catalytic activity and other properties. , 1974, Biochemical and biophysical research communications.

[77]  Y. Imai,et al.  A gel-electrophoretically homogeneous preparation of cytochrome P-450 from liver microsomes of phenobarbital-pretreated rabbits. , 1974, Biochemical and biophysical research communications.

[78]  W. Levin,et al.  Purification and characterization of hepatic microsomal cytochrome P-450. , 1990, Pharmacology & therapeutics.

[79]  J. Schenkman,et al.  Effects of testosterone and growth hormone treatment on hepatic microsomal P450 expression in the diabetic rat. , 1990, Molecular pharmacology.

[80]  J. Schenkman,et al.  Physiological and pathophysiological alterations in rat hepatic cytochrome P-450. , 1989, Drug metabolism reviews.

[81]  M. J. Coon,et al.  Cytochrome P-450 isozymes 2 and 5 in rabbit lung and liver. Comparisons of structure and inducibility. , 1987, Drug metabolism and disposition: the biological fate of chemicals.

[82]  S. Yamamoto,et al.  Isolation of cytochrome P-450 highly active in prostaglandin omega-hydroxylation from lung microsomes of rabbits treated with progesterone. , 1984, Journal of biochemistry.

[83]  E. Hodgson,et al.  Purification and reconstitution of the cytochrome P-450 monooxygenase system from uninduced mouse liver , 1983 .