Recent advances of antioxidant low-dimensional carbon materials for biomedical applications

As the primary cause of many tissue damage and diseases, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are well known to be extremely harmful to a variety of biological components in cells including lipids, proteins and DNA. Numerous antioxidative nanomaterials have been artificially designed and rationally synthesized to protect cells from the oxidative damage caused by reactive oxygen species/reactive nitrogen species. Recent studies demonstrate that low dimensional carbon antioxidative nanomaterials have received a lot of attention owing to their tiny nanoscales and unique physicochemical property. As a result, a brief overview of recent advancements in antioxidant low-dimensional carbon materials is provided. Typically, carbon nanomaterials are classified according to their nanostructure dimensions, which are zero-dimension, one-dimension, and two-dimension. Last but not least, the challenges and perspectives of these high-performance low-dimensional materials in biomedical fields and further clinical usages are discussed as well.

[1]  Jiani Xie,et al.  External Use of Nano-graphdiyne Hydrogel for Skin Radioprotection via Both Physically Shielding of Low-energy X-ray and Chemically Scavenging of Broad-spectrum Free Radicals , 2021, Chemical Engineering Journal.

[2]  X. Qu,et al.  Phenol-like group functionalized graphene quantum dots structurally mimicking natural antioxidants for highly efficient acute kidney injury treatment† , 2020, Chemical science.

[3]  Huibo Wang,et al.  Carbon dots derived from citric acid and glutathione as a high-efficient intracellular ROS scavenger for alleviating the lipopolysaccharide induced inflammation in macrophage. , 2020, ACS applied materials & interfaces.

[4]  L. Miao,et al.  Integrated cascade nanozyme catalyzes in vivo ROS scavenging for anti-inflammatory therapy , 2020, Science Advances.

[5]  K. Xi,et al.  Phenylenediamine-based Carbon Nanodots Alleviate Acute Kidney Injury via Preferential Renal Accumulation and Antioxidant Capacity. , 2020, ACS applied materials & interfaces.

[6]  O. Crosby,et al.  nanotubes , 2020, Catalysis from A to Z.

[7]  Yuliang Zhao,et al.  Graphdiyne nanoradioprotector with efficient free radical scavenging ability for mitigating radiation-induced gastrointestinal tract damage. , 2020, Biomaterials.

[8]  A. Zhang,et al.  Facile Synthesis of Water-Soluble Fullerene (C60) Nanoparticles via Mussel-Inspired Chemistry as Efficient Antioxidants , 2019, Nanomaterials.

[9]  Baolin Guo,et al.  Mussel-inspired, antibacterial, conductive, antioxidant, injectable composite hydrogel wound dressing to promote the regeneration of infected skin. , 2019, Journal of colloid and interface science.

[10]  Jinjun Shi,et al.  Antioxidative nanomaterials and biomedical applications , 2019, Nano Today.

[11]  Feng Cheng,et al.  Green Synthesis of Fluorescent Carbon Dots from Gynostemma for Bioimaging and Antioxidant in Zebrafish. , 2019, ACS applied materials & interfaces.

[12]  Chunru Wang,et al.  Amino acid modified [70] fullerene derivatives with high radical scavenging activity as promising bodyguards for chemotherapy protection , 2018, Scientific Reports.

[13]  Xiurong Yang,et al.  Polydopamine Nanoparticles as Efficient Scavengers for Reactive Oxygen Species in Periodontal Disease. , 2018, ACS nano.

[14]  Xiaogang Qu,et al.  Carbon Nanozymes: Enzymatic Properties, Catalytic Mechanism, and Applications. , 2018, Angewandte Chemie.

[15]  Yuan Cheng,et al.  ROS scavenging Mn3O4 nanozymes for in vivo anti-inflammation† †Electronic supplementary information (ESI) available: Additional figures and associated discussions. See DOI: 10.1039/c7sc05476a , 2018, Chemical science.

[16]  Chunru Wang,et al.  Biocompatible [60]/[70] Fullerenols: Potent Defense against Oxidative Injury Induced by Reduplicative Chemotherapy. , 2017, ACS applied materials & interfaces.

[17]  Huaping Xu,et al.  Selenium-Doped Carbon Quantum Dots for Free-Radical Scavenging. , 2017, Angewandte Chemie.

[18]  X. Liu,et al.  Electrochemical synthesis of phosphorus-doped graphene quantum dots for free radical scavenging. , 2017, Physical chemistry chemical physics : PCCP.

[19]  X. Qu,et al.  A GO-Se nanocomposite as an antioxidant nanozyme for cytoprotection. , 2017, Chemical communications.

[20]  R. Du,et al.  Comprehensive Insights into the Multi-Antioxidative Mechanisms of Melanin Nanoparticles and Their Application To Protect Brain from Injury in Ischemic Stroke. , 2017, Journal of the American Chemical Society.

[21]  Z. Chai,et al.  Crossover between Anti- and Pro-oxidant Activities of Graphene Quantum Dots in the Absence or Presence of Light. , 2016, ACS nano.

[22]  S. C. Sharma,et al.  Cinnamon supported facile green reduction of graphene oxide, its dye elimination and antioxidant activities , 2015 .

[23]  Y. Shieh,et al.  Radical scavenging efficiencies of modified and microwave-treated multiwalled carbon nanotubes , 2014 .

[24]  R. Hurt,et al.  Antioxidant chemistry of graphene-based materials and its role in oxidation protection technology. , 2014, Nanoscale.

[25]  Shengshui Hu,et al.  Facile synthesis of water-soluble fullerene–graphene oxide composites for electrodeposition of phosphotungstic acid-based electrocatalysts , 2013 .

[26]  X. Fang,et al.  C70-carboxyfullerenes as efficient antioxidants to protect cells against oxidative-induced stress. , 2013, ACS applied materials & interfaces.

[27]  N. Lee,et al.  Amine-modified single-walled carbon nanotubes protect neurons from injury in a rat stroke model. , 2011, Nature nanotechnology.

[28]  Annia Galano,et al.  Influence of Diameter, Length, and Chirality of Single-Walled Carbon Nanotubes on Their Free Radical Scavenging Capability , 2009 .

[29]  James M Tour,et al.  Antioxidant single-walled carbon nanotubes. , 2009, Journal of the American Chemical Society.

[30]  Paul C. Wang,et al.  The scavenging of reactive oxygen species and the potential for cell protection by functionalized fullerene materials. , 2009, Biomaterials.