Fine‐mapping and replication of EWAS loci harboring putative epigenetic alterations associated with AD neuropathology in a large collection of human brain tissue samples
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P. D. De Jager | Lei Yu | Z. Huo | Tongjun Gu | Jingyun Yang | David A. Bennett | Jinying Zhao | H. Palma-Gudiel | Yanling Wang | Cheng Gao | Peng Jin | Zhiguang Huo | Lei Yu | Helena Palma-Gudiel
[1] Benjamin A. Logsdon,et al. Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue , 2021, Nature Communications.
[2] D. Bennett,et al. Human Brain and Blood N-Glycome Profiling in Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias , 2021, Frontiers in Aging Neuroscience.
[3] C. Jack,et al. Contribution of Alzheimer's biomarkers and risk factors to cognitive impairment and decline across the Alzheimer's disease continuum , 2021, Alzheimer's & dementia : the journal of the Alzheimer's Association.
[4] W. M. van der Flier,et al. Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores , 2021, Nature Communications.
[5] Daniel J. Gaffney,et al. Genome-wide meta-analysis, fine-mapping, and integrative prioritization implicate new Alzheimer’s disease risk genes , 2021, Nature Genetics.
[6] Chunshui Yu,et al. Hippocampal transcriptome-wide association study and neurobiological pathway analysis for Alzheimer’s disease , 2021, PLoS genetics.
[7] Weiqi Chen,et al. Glycemic traits and Alzheimer’s disease: a Mendelian randomization study , 2020, Aging.
[8] Nick C Fox,et al. New insights on the genetic etiology of Alzheimer’s and related dementia , 2020 .
[9] Charles C. White,et al. Neuroticism alters the transcriptome of the frontal cortex to contribute to the cognitive decline and onset of Alzheimer’s disease , 2020, bioRxiv.
[10] Naaheed Mukadam,et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission , 2020, The Lancet.
[11] Stephen C. J. Parker,et al. The Trans-Ancestral Genomic Architecture of Glycemic Traits , 2020, Nature Genetics.
[12] Benjamin A. Logsdon,et al. Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer’s disease , 2020, Genome Medicine.
[13] Alan J. Thomas,et al. A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex , 2020, Nature Communications.
[14] M. Bozzali,et al. Cerebello-Cortical Alterations Linked to Cognitive and Social Problems in Patients With Spastic Paraplegia Type 7: A Preliminary Study , 2020, Frontiers in Neurology.
[15] E. Colicino,et al. DNA Methylation–Based Biomarkers of Environmental Exposures for Human Population Studies , 2020, Current Environmental Health Reports.
[16] James B. Brewer,et al. Brain cell type–specific enhancer–promoter interactome maps and disease-risk association , 2019, Science.
[17] P. Barbarino,et al. THE STATE OF THE ART OF DEMENTIA RESEARCH: NEW FRONTIERS , 2019, Alzheimer's & Dementia.
[18] Trevor Hastie,et al. Genetics of 35 blood and urine biomarkers in the UK Biobank , 2020, Nature Genetics.
[19] Arturas Petronis,et al. Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms , 2019, Nature Communications.
[20] V. Vaccarino,et al. DNA Methylation of Five Core Circadian Genes Jointly Contributes to Glucose Metabolism: A Gene-Set Analysis in Monozygotic Twins , 2019, Front. Genet..
[21] Nick C Fox,et al. Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing , 2019, Nature Genetics.
[22] J. Mill,et al. A cross-brain regions study of ANK1 DNA methylation in different neurodegenerative diseases , 2019, Neurobiology of Aging.
[23] Anne E Carpenter,et al. BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 implicated in Tau pathology , 2019, bioRxiv.
[24] Timothy J. Hohman,et al. Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk , 2019, Nature Genetics.
[25] Bin Zhang,et al. Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer’s disease susceptibility , 2018, Nature Genetics.
[26] Jun Xie,et al. Cauchy Combination Test: A Powerful Test With Analytic p-Value Calculation Under Arbitrary Dependency Structures , 2018, Journal of the American Statistical Association.
[27] F. Piferrer,et al. Consistent inverse correlation between DNA methylation of the first intron and gene expression across tissues and species , 2018, Epigenetics & Chromatin.
[28] C. Jack,et al. NIA-AA Research Framework: Toward a biological definition of Alzheimer’s disease , 2018, Alzheimer's & Dementia.
[29] U. Muthane,et al. Discovery of a frameshift mutation in podocalyxin-like (PODXL) gene, coding for a neural adhesion molecule, as causal for autosomal-recessive juvenile Parkinsonism , 2016, Journal of Medical Genetics.
[30] D. Bennett,et al. Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease , 2014, Nature Neuroscience.
[31] Manolis Kellis,et al. Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci , 2014 .
[32] Manolis Kellis,et al. Alzheimery's disease pathology is associated with early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci , 2014, Nature Neuroscience.
[33] Francis Eustache,et al. Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease , 2013, NeuroImage: Clinical.
[34] J. Schneider,et al. Overview and findings from the religious orders study. , 2012, Current Alzheimer research.
[35] J. Schneider,et al. Overview and findings from the rush Memory and Aging Project. , 2012, Current Alzheimer research.
[36] Peter A. Jones. Functions of DNA methylation: islands, start sites, gene bodies and beyond , 2012, Nature Reviews Genetics.
[37] Andrew E. Jaffe,et al. Bioinformatics Applications Note Gene Expression the Sva Package for Removing Batch Effects and Other Unwanted Variation in High-throughput Experiments , 2022 .
[38] K. Gunderson,et al. High density DNA methylation array with single CpG site resolution. , 2011, Genomics.
[39] B. Hyman,et al. Neuropathological alterations in Alzheimer disease. , 2011, Cold Spring Harbor perspectives in medicine.
[40] N. Maglaveras,et al. Human epigenome data reveal increased CpG methylation in alternatively spliced sites and putative exonic splicing enhancers. , 2011, DNA and cell biology.
[41] E. Soriano,et al. Podocalyxin Is a Novel Polysialylated Neural Adhesion Protein with Multiple Roles in Neural Development and Synapse Formation , 2010, PloS one.
[42] J. Nielsen,et al. The role of podocalyxin in health and disease. , 2009, Journal of the American Society of Nephrology : JASN.
[43] N. Bresolin,et al. A clinical, genetic, and biochemical characterization of SPG7 mutations in a large cohort of patients with hereditary spastic paraplegia , 2008, Human mutation.
[44] Sergio Cocozza,et al. Spastic Paraplegia and OXPHOS Impairment Caused by Mutations in Paraplegin, a Nuclear-Encoded Mitochondrial Metalloprotease , 1998, Cell.