We present an application of the Vertex Morphing Method to aircraft preliminary design. Vertex Morphing is a node-based shape optimization technique, that unifies shape control, mesh-regularization and sensitivity filtering. Since it directly uses surface nodes of the given discrete model, it is particularly useful to explore the design space at a minimum modelling effort. It also allows for effective shape optimization where another parametrization is not obvious or even infeasible. Hence, it represents an alternative to the application of an experience-based shape parametrization. Particular problem of interest is the aerodynamic shape optimization of a flexible wing. Given this multidisciplinary problem, we investigate the Vertex Morphing method in terms of possible design improvements and quality of the final design. Furthermore, we present a generic implementation of the Vertex Morphing method in an established open-source software framework dedicated to multiphysics in general. The implementation provides a standalone optimizer with a python interface, that allows any interested user to conveniently try Vertex Morphing for own problems from different physical applications (e.g. structures or aerodynamics). An outlook on the shape optimization of a forwardswept wing aircraft finally highlights capabilities of the implementation.