The role of deoxynucleoside triphosphate pools in the inhibition of DNA-excision repair and replication in human cells by hydroxyurea.

[1]  R. Snyder.  Effects of nucleotide pool imbalances on the excision repair of ultraviolet-induced damage in the DNA of human diploid fibroblasts. , 1985, Basic life sciences.

[2]  R. Snyder,et al.  The inhibition of ultraviolet radiation-induced DNA repair in human diploid fibroblasts by arabinofuranosyl nucleosides. , 1984, Chemico-biological interactions.

[3]  R. Snyder.  Deoxyribonucleoside triphosphate pools in human diploid fibroblasts and their modulation by hydroxyurea and deoxynucleosides. , 1984, Biochemical pharmacology.

[4]  T. Seno,et al.  Unusual sensitivity to bleomycin and joint resistance to 9-beta-D-arabinofuranosyladenine and 1-beta-D-arabinofuranosylcytosine of mouse FM3A cell mutants with altered ribonucleotide reductase and thymidylate synthase. , 1983, Cancer research.

[5]  W. Przybyszewski,et al.  Protection against hydroxyurea-induced cytotoxic effects in L5178Y cells by free radical scavengers. , 1982, Cancer letters.

[6]  G. Tyrsted.  Effect of hydroxyurea and 5-fluorodeoxyuridine on deoxyribonucleoside triphosphate pools early in phytohemagglutinin-stimulated human lymphocytes. , 1982, Biochemical pharmacology.

[7]  R. Snyder,et al.  Differential responses of log and stationary phase human fibroblasts to inhibition of DNA repair by aphidicolin. , 1982, Biochimica et biophysica acta.

[8]  D. Hunting,et al.  Determination of deoxyribonucleoside triphosphates using DNA polymerase: a critical evaluation. , 1981, Canadian journal of biochemistry.

[9]  J. G. Cory,et al.  Effect of iron-chelating agents on inhibitors of ribonucleotide reductase. , 1981, Biochemical pharmacology.

[10]  D. Forsdyke,et al.  Isotope-dilution analysis of the effects of deoxyguanosine and deoxyadenosine on the incorporation of thymidine and deoxycytidine by hydroxyurea-treated thymus cells. , 1980, The Biochemical journal.

[11]  C. Mathews,et al.  Detection of activities that interfere with the enzymatic assay of deoxyribonucleoside 5'-triphosphates. , 1980, The Journal of biological chemistry.

[12]  A. Pardee,et al.  Multienzyme complex for metabolic channeling in mammalian DNA replication. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[13]  R. Blevins,et al.  Inhibition of DNA repair in ultraviolet-irradiated human cells by hydroxyurea. , 1979, Biochimica et biophysica acta.

[14]  K. Erixon,et al.  Single-strand breaks in DNA during repair of UV-induced damage in normal human and xeroderma pigmentosum cells as determined by alkaline DNA unwinding and hydroxylapatite chromatography: effects of hydroxyurea, 5-fluorodeoxyuridine and 1-beta-D-arabinofuranosylcytosine on the kinetics of repair. , 1979, Mutation research.

[15]  J. Clarkson.  Enhancement of repair replication in mammalian cells by hydroxyurea. , 1978, Mutation research.

[16]  B. Sjöberg,et al.  The tyrosine free radical in ribonucleotide reductase from Escherichia coli. , 1978, The Journal of biological chemistry.

[17]  R. Wohlhueter,et al.  Transport and metabolism of deoxycytidine and 1-beta-D-arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation, and regulation of triphosphate synthesis. , 1978, Cancer research.

[18]  A. Collins,et al.  Reversal of the changes in DNA and chromosome structure which follow the inhibition of UV-induced repair in human cells. , 1978, Biochemical and biophysical research communications.

[19]  P. Reichard.  From deoxynucleotides to DNA synthesis. , 1978, Federation proceedings.

[20]  M. Smulson,et al.  Effect of methotrexate and 5-fluorodeoxyuridine on ribonucleotide reductase activity in mammalian cells. , 1977, Cancer research.

[21]  J. Little,et al.  Enhancement of UV-induced unscheduled DNA synthesis by hydroxyurea. Demonstration by combined biochemical and autoradiographic techniques. , 1977, Experimental cell research.

[22]  A. Collins.  DNA damage in ultraviolet-irradiated HeLa and CHO-Kl cells examined by alkaline lysis and hydroxyapatite chromatography. , 1977, Biochimica et biophysica acta.

[23]  B. Sjöberg,et al.  Nature of the free radical in ribonucleotide reductase from Escherichia coli. , 1977, The Journal of biological chemistry.

[24]  A. Collins,et al.  The inhibition of repair in UV irradiated human cells. , 1977, Mutation research.

[25]  P. Hanawalt,et al.  Repair replication in human cells. Simplified determination utilizing hydroxyurea. , 1976, Biochimica et biophysica acta.

[26]  P. Plagemann,et al.  Intracellular conversions of deoxyribonucleosides by Novikoff rat hepatoma cells and effects of hydroxyurea , 1974, Journal of cellular physiology.

[27]  E. Vitols,et al.  Ribonucleotide reductase activity during the cell cycle of Saccharomyces cerevisiae. , 1973, Archives of biochemistry and biophysics.

[28]  P. Reichard,et al.  Control of deoxyribonucleotide synthesis in vitro and in vivo. , 1972, Advances in enzyme regulation.

[29]  R. Adams,et al.  Deoxyribonucleoside triphosphate pools in synchronized and drug-inhibited L 929 cells. , 1971, Biochimica et biophysica acta.

[30]  E. Ben-hur,et al.  DNA REPAIR IN ULTRAVIOLET LIGHT IRRADIATED HeLa CELLS AND ITS REVERSIBLE INHIBITION BY HYDROXYUREA , 1971, Photochemistry and photobiology.

[31]  B. Nordenskjöld,et al.  Effects of hydroxyurea and 1-beta-D-arabinofuranosyl-cytosine on deoxyribonucleotide pools in mouse embryo cells. , 1971, European journal of biochemistry.

[32]  H. Rosenkranz,et al.  Degradation of DNA by carbamoyloxyurea--an oxidation product of hydroxyurea. , 1969, Biochimica et biophysica acta.

[33]  J. Cleaver.  Repair replication of mammalian cell DNA: effects of compounds that inhibit DNA synthesis or dark repair. , 1969, Radiation research.

[34]  P. Reichard,et al.  Inhibition of ribonucleoside diphosphate reductase by hydroxyurea. , 1968, Cancer research.

[35]  J. Lindsay,et al.  Hydroxyurea reversal of inhibition and use as a cell-synchronizing agent. , 1967, The Journal of biological chemistry.