MRI features of spongiform leukoencephalopathy following heroin inhalation

A 26-year-old man with a history of heroin inhalation presented with impaired motor, speech, and cognitive functions, reduced muscle strength, hyperactive deep tendon reflexes, and intact light-tough, vibration, and pinprick sensitivity. T2-weighted MRI revealed symmetric hyperintensity in white matter tracts, consistent with spongiform degeneration and demyelination (figure 1).1 Involvement of …