Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA
暂无分享,去创建一个
W. Mark Saltzman | Kim A. Woodrow | Yen Cu | W. Saltzman | K. Woodrow | J. Saucier-Sawyer | C. Booth | Carmen J. Booth | Jennifer K. Saucier-Sawyer | Y. Cu | M. J. Wood | Monica J. Wood
[1] Daniel G. Anderson,et al. Knocking down barriers: advances in siRNA delivery , 2009, Nature Reviews Drug Discovery.
[2] John J. Rossi,et al. The promises and pitfalls of RNA-interference-based therapeutics , 2009, Nature.
[3] A. Judge,et al. Misinterpreting the therapeutic effects of small interfering RNA caused by immune stimulation. , 2008, Human gene therapy.
[4] Dale L. Greiner,et al. T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice , 2008, Cell.
[5] Christopher J. Miller,et al. Whither or Wither Microbicides? , 2008, Science.
[6] David P Wilson,et al. The paradoxical effects of using antiretroviral-based microbicides to control HIV epidemics , 2008, Proceedings of the National Academy of Sciences.
[7] Junji Kato,et al. Resolution of liver cirrhosis using vitamin A–coupled liposomes to deliver siRNA against a collagen-specific chaperone , 2008, Nature Biotechnology.
[8] Naoyuki Murata,et al. Anti-tumor effects of anti-VEGF siRNA encapsulated with PLGA microspheres in mice. , 2008, Journal of controlled release : official journal of the Controlled Release Society.
[9] D. Peer,et al. Systemic Leukocyte-Directed siRNA Delivery Revealing Cyclin D1 as an Anti-Inflammatory Target , 2008, Science.
[10] F. Liu,et al. Several serum proteins significantly decrease inflammatory response to lipid-based non-viral vectors. , 2008, Molecular therapy : the journal of the American Society of Gene Therapy.
[11] Shubiao Zhang,et al. Cationic lipids and polymers mediated vectors for delivery of siRNA. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[12] M. Breunig,et al. Breaking up the correlation between efficacy and toxicity for nonviral gene delivery , 2007, Proceedings of the National Academy of Sciences.
[13] J. Vishwanatha,et al. Polymeric nanoparticles for sustained down-regulation of annexin A2 lead to reduction in proliferation and migration of prostate cancer cells , 2007 .
[14] Justin Hanes,et al. Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus , 2007, Proceedings of the National Academy of Sciences.
[15] W. Gu,et al. Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenes , 2006, Cancer Gene Therapy.
[16] Xudong Yuan,et al. SiRNA drug delivery by biodegradable polymeric nanoparticles. , 2006, Journal of nanoscience and nanotechnology.
[17] Shubiao Zhang,et al. Toxicity of cationic lipids and cationic polymers in gene delivery. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[18] Y. Barenholz,et al. Lipoplexes prepared from cationic liposomes and mammalian DNA induce CpG‐independent, direct cytotoxic effects in cell cultures and in mice , 2006, The journal of gene medicine.
[19] Amy C Richards Grayson,et al. Biophysical and Structural Characterization of Polyethylenimine-Mediated siRNA Delivery in Vitro , 2006, Pharmaceutical Research.
[20] Sung Wan Kim,et al. Current status of polymeric gene delivery systems. , 2006, Advanced drug delivery reviews.
[21] Matthias John,et al. RNAi-mediated gene silencing in non-human primates , 2006, Nature.
[22] J. Richie,et al. Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[23] J. Lieberman,et al. An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection , 2006, Nature.
[24] U. Bachrach. Naturally occurring polyamines: interaction with macromolecules. , 2005, Current protein & peptide science.
[25] John P. Moore,et al. Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus–cell fusion , 2005, Nature.
[26] Keith Bowman,et al. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs , 2005, Nature Biotechnology.
[27] Judy Lieberman,et al. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors , 2005, Nature Biotechnology.
[28] Feng Liu,et al. Implications of pharmacokinetic behavior of lipoplex for its inflammatory toxicity. , 2005, Advanced drug delivery reviews.
[29] Wenlei Jiang,et al. Biodegradable poly(lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigens. , 2005, Advanced drug delivery reviews.
[30] I. Adcock,et al. The Journal of Inflammation , 2004, Journal of Inflammation.
[31] G. Hannon,et al. Unlocking the potential of the human genome with RNA interference , 2004, Nature.
[32] X. Zhu,et al. Polymer microspheres for controlled drug release. , 2004, International journal of pharmaceutics.
[33] Stephen P. Fox,et al. Sustained Polymeric Delivery of Gene Silencing Antisense ODNs, siRNA, DNAzymes and Ribozymes: In Vitro and In Vivo Studies , 2004, Journal of drug targeting.
[34] E. Gerner,et al. Polyamine-dependent gene expression , 2003, Cellular and Molecular Life Sciences CMLS.
[35] M. Manns,et al. Caspase 8 small interfering RNA prevents acute liver failure in mice , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[36] Sandra L. Schmid,et al. Regulated portals of entry into the cell , 2003, Nature.
[37] John P. Moore,et al. Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120 , 2003, Nature Medicine.
[38] Jayanth Panyam,et al. Dynamics of Endocytosis and Exocytosis of Poly(D,L-Lactide-co-Glycolide) Nanoparticles in Vascular Smooth Muscle Cells , 2003, Pharmaceutical Research.
[39] W. Saltzman,et al. Gene expression and mucosal immune responses after vaginal DNA immunization in mice using a controlled delivery matrix. , 2003, Journal of controlled release : official journal of the Controlled Release Society.
[40] A. Stone. Microbicides: a new approach to preventing HIV and other sexually transmitted infections , 2002, Nature Reviews Drug Discovery.
[41] Jayanth Panyam,et al. Rapid endo‐lysosomal escape of poly(DL‐lactide‐coglycolide) nanoparticles: implications for drug and gene delivery , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[42] J. Lieberman,et al. siRNA-directed inhibition of HIV-1 infection , 2002, Nature Medicine.
[43] A. I. Yudin,et al. Diffusion of macromolecules and virus-like particles in human cervical mucus. , 2001, Biophysical journal.
[44] T. Thomas,et al. Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications , 2001, Cellular and Molecular Life Sciences CMLS.
[45] Sanchita Bhattacharya,et al. Characterization of cationic lipid-protamine–DNA (LPD) complexes for intravenous gene delivery , 1998, Gene Therapy.
[46] Scott D. Putney,et al. Improving protein therapeutics with sustained-release formulations , 1998, Nature Biotechnology.
[47] K. Whaley,et al. Controlled release of antibodies for long-term topical passive immunoprotection of female mice against genital herpes , 1996, Nature Biotechnology.
[48] J. Patton,et al. (D) Routes of delivery: Case studies , 1992 .
[49] L. Illum,et al. (D) Routes of delivery: Case studies , 1992 .