MANF ameliorates DSS-induced mouse colitis via restricting Ly6ChiCX3CR1int macrophage transformation and suppressing CHOP-BATF2 signaling pathway

[1]  S. Heath,et al.  Systemic inflammation in pre-clinical ulcerative colitis. , 2021, Gastroenterology.

[2]  M. Macias,et al.  Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease , 2021, Nature Communications.

[3]  Jianming Xu,et al.  Hepatocyte-derived MANF is protective for rifampicin-induced cholestatic hepatic injury via inhibiting ATF4-CHOP signal activation. , 2020, Free radical biology & medicine.

[4]  Yujun Shen,et al.  Hepatocyte‐derived MANF alleviates hepatic ischaemia‐reperfusion injury via regulating endoplasmic reticulum stress‐induced apoptosis in mice , 2020, Liver international : official journal of the International Association for the Study of the Liver.

[5]  Songguo Zheng,et al.  ECM1 is an essential factor for the determination of M1 macrophage polarization in IBD in response to LPS stimulation , 2020, Proceedings of the National Academy of Sciences.

[6]  Licheng Wu,et al.  Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase 3 Expression. , 2019, Gastroenterology.

[7]  G. Miyoshi,et al.  Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network , 2019, Nature Communications.

[8]  Chuan-sheng Wei,et al.  MANF regulates splenic macrophage differentiation in mice. , 2019, Immunology letters.

[9]  O. Pabst,et al.  Inflammation triggers immediate rather than progressive changes in monocyte differentiation in the small intestine , 2019, Nature Communications.

[10]  G. Matteoli,et al.  Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD , 2019, Nature Reviews Gastroenterology & Hepatology.

[11]  M. Neurath.  Targeting immune cell circuits and trafficking in inflammatory bowel disease , 2019, Nature Immunology.

[12]  H. Ji,et al.  YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis. , 2019, Cell reports.

[13]  Hongqiang Cheng,et al.  Phosphatase Shp2 exacerbates intestinal inflammation by disrupting macrophage responsiveness to interleukin-10 , 2019, The Journal of experimental medicine.

[14]  Chen-Yu Liao,et al.  MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage , 2018, Nature Metabolism.

[15]  Daniel E. Zak,et al.  Batf2 differentially regulates tissue immunopathology in Type 1 and Type 2 diseases , 2018, Mucosal Immunology.

[16]  I. Belevich,et al.  MANF Is Required for the Postnatal Expansion and Maintenance of Pancreatic β-Cell Mass in Mice , 2018, Diabetes.

[17]  M. Gershwin,et al.  The CXC Chemokine Receptor 3 Inhibits Autoimmune Cholangitis via CD8+ T Cells but Promotes Colitis via CD4+ T Cells , 2018, Front. Immunol..

[18]  K. Kharbanda,et al.  Dextran sodium sulfate colitis murine model: An indispensable tool for advancing our understanding of inflammatory bowel diseases pathogenesis , 2017, World journal of gastroenterology.

[19]  S. Akira,et al.  Antitumor effect of Batf2 through IL-12 p40 up-regulation in tumor-associated macrophages , 2017, Proceedings of the National Academy of Sciences.

[20]  L. Öhman,et al.  Mucosal immune system of the gastrointestinal tract: maintaining balance between the good and the bad , 2017, Scandinavian journal of gastroenterology.

[21]  J. Grainger,et al.  Macrophages in gastrointestinal homeostasis and inflammation , 2017, Pflügers Archiv - European Journal of Physiology.

[22]  H. Jasper,et al.  Immune modulation by MANF promotes tissue repair and regenerative success in the retina , 2016, Science.

[23]  C. Fiocchi,et al.  Immunopathogenesis of IBD: current state of the art , 2016, Nature Reviews Gastroenterology &Hepatology.

[24]  G. Kaplan,et al.  The global burden of IBD: from 2015 to 2025 , 2015, Nature Reviews Gastroenterology &Hepatology.

[25]  L. Taams,et al.  The Interplay Between Monocytes/Macrophages and CD4+ T Cell Subsets in Rheumatoid Arthritis , 2015, Front. Immunol..

[26]  S. Fang,et al.  ER stress-inducible protein MANF selectively expresses in human spleen. , 2015, Human immunology.

[27]  Reto Guler,et al.  Targeting Batf2 for infectious diseases and cancer , 2015, Oncotarget.

[28]  Jay W. Shin,et al.  Batf2/Irf1 Induces Inflammatory Responses in Classically Activated Macrophages, Lipopolysaccharides, and Mycobacterial Infection , 2015, The Journal of Immunology.

[29]  J. Uney,et al.  Enhanced efficacy of the CDNF/MANF family by combined intranigral overexpression in the 6-OHDA rat model of Parkinson's disease. , 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

[30]  Markus F. Neurath,et al.  Cytokines in inflammatory bowel disease , 2014, Nature Reviews Immunology.

[31]  J. Gálvez.  Role of Th17 Cells in the Pathogenesis of Human IBD , 2014, ISRN inflammation.

[32]  B. Chassaing,et al.  Dextran Sulfate Sodium (DSS)‐Induced Colitis in Mice , 2014, Current protocols in immunology.

[33]  A. Kaser,et al.  Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation , 2013, Gut.

[34]  E. Shin,et al.  Genetic variants in the IL12B gene are associated with inflammatory bowel diseases in the Korean population , 2013, Journal of gastroenterology and hepatology.

[35]  K. Murphy,et al.  Specificity through cooperation: BATF–IRF interactions control immune-regulatory networks , 2013, Nature Reviews Immunology.

[36]  B. Malissen,et al.  Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors , 2012, Mucosal Immunology.

[37]  Ansuman T. Satpathy,et al.  Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells. , 2012, Immunity.

[38]  C. Glembotski.  Functions for the cardiomyokine, MANF, in cardioprotection, hypertrophy and heart failure. , 2011, Journal of molecular and cellular cardiology.

[39]  C. Wijmenga,et al.  Functional polymorphism in IL12B promoter site is associated with ulcerative colitis. , 2011, Inflammatory bowel diseases.

[40]  W. Strober,et al.  Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases. , 2011, Gastroenterology.

[41]  E. Hoster,et al.  Strong overexpression of CXCR3 axis components in childhood inflammatory bowel disease , 2010, Inflammatory bowel diseases.

[42]  M. Raffatellu,et al.  Th17 Cytokines and the Gut Mucosal Barrier , 2010, Journal of Clinical Immunology.

[43]  D. Rampton,et al.  DIFFERENTIAL REGULATION OF INTERLEUKIN-17 AND INTERFERON- PRODUCTION IN INFLAMMATORY BOWEL DISEASE , 2011 .

[44]  L. Mayer,et al.  Evolving paradigms in the pathogenesis of IBD , 2009, Journal of Gastroenterology.

[45]  O. Lindvall,et al.  MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain , 2008, Molecular and Cellular Neuroscience.

[46]  D. Rubin,et al.  Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation , 2008, Laboratory Investigation.

[47]  S. Fang,et al.  Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death. , 2008, Experimental cell research.

[48]  U Wahnschaffe,et al.  Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease , 2006, Gut.

[49]  R. D. Hatton,et al.  Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages , 2005, Nature Immunology.

[50]  K. Kaukinen,et al.  Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells , 2005, Laboratory Investigation.

[51]  S. Oyadomari,et al.  Roles of CHOP/GADD153 in endoplasmic reticulum stress , 2004, Cell Death and Differentiation.

[52]  T. Abe,et al.  mRNA of MUC2 is stimulated by IL‐4, IL‐13 or TNF‐α through a mitogen‐activated protein kinase pathway in human colon cancer cells , 2003, Immunology and cell biology.

[53]  A. Andoh,et al.  Increased expression of interleukin 17 in inflammatory bowel disease , 2003, Gut.

[54]  K. Abrams,et al.  The risk of colorectal cancer in ulcerative colitis: a meta-analysis , 2001, Gut.

[55]  M. Neurath,et al.  Antibodies to interleukin 12 abrogate established experimental colitis in mice , 1995, The Journal of experimental medicine.

[56]  C. Elson,et al.  Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice. , 1994, Gastroenterology.