论文信息 - Reaction of ketohexoses with acid in certain non-aqueous sugar solvents

Reaction of ketohexoses with acid in certain non-aqueous sugar solvents

Ketohexoses or potential ketohexoses react rapidly with acids at high temperatures in non-aqueous solvents (containing the grouping R·O·C·C·OH in their structures1) to produce 5-hydroxymethyl-furfural (HMF). HMF reacts further to give the solvent ether (e.g., II, III or IV) in a slow reaction. Several of these ethers have been reduced partially to mono-ethers of 2,5-di(hydroxymethyl)furan (V, VI or VII) and fully to mono-ethers of 2,5-di(hydroxymethyl)tetrahydrofuran (VIII, IX or X).

C. Moye | R. Goldsack

[1] J. Mason,et al. Solid Derivatives of Monoalkyl Ethers of Ethylene Glycol and Diethylene Glycol. II , 1940 .

[2] J. F. Harris,et al. A sample applicator for chromatographic paper and its use for 5-hydroxymethyl-2-furaldehyde and levulinic acid analysis , 1961 .