Smad signalling in the ovary
暂无分享,去创建一个
[1] F. Otsuka,et al. The role of bone morphogenetic proteins in ovarian function. , 2019, Reproduction (Cambridge, England) Supplement.
[2] R. Robker,et al. Null mutation in transforming growth factor beta1 disrupts ovarian function and causes oocyte incompetence and early embryo arrest. , 2006, Endocrinology.
[3] J. Juengel,et al. Physiological effects of major genes affecting ovulation rate in sheep , 2005, Genetics Selection Evolution.
[4] C. Sturgis,et al. The development of a mouse model of ovarian endosalpingiosis. , 2005, Endocrinology.
[5] R. Gilchrist,et al. Oocytes prevent cumulus cell apoptosis by maintaining a morphogenic paracrine gradient of bone morphogenetic proteins , 2005, Journal of Cell Science.
[6] V. Rosen,et al. BMP-3 is a novel inhibitor of both activin and BMP-4 signaling in Xenopus embryos. , 2005, Developmental biology.
[7] C. Mummery,et al. Altered primordial germ cell migration in the absence of transforming growth factor beta signaling via ALK5. , 2005, Developmental biology.
[8] R. Gilchrist,et al. Role of oocyte-secreted growth differentiation factor 9 in the regulation of mouse cumulus expansion. , 2005, Endocrinology.
[9] A. Byskov,et al. Anti-Müllerian hormone initiates growth of human primordial follicles in vitro , 2005, Molecular and Cellular Endocrinology.
[10] R. van den Hurk,et al. Formation of mammalian oocytes and their growth, differentiation and maturation within ovarian follicles. , 2005, Theriogenology.
[11] D. Mottershead,et al. Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulosa cell function in ruminants. , 2005, Reproduction.
[12] D. Mottershead,et al. Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulosa cell function. , 2005, Reproduction.
[13] H. Schnaper,et al. The Role of Internalization in Transforming Growth Factor β1-induced Smad2 Association with Smad Anchor for Receptor Activation (SARA) and Smad2-dependent Signaling in Human Mesangial Cells* , 2005, Journal of Biological Chemistry.
[14] M. Matzuk,et al. Genetic models for transforming growth factor β superfamily signaling in ovarian follicle development , 2004, Molecular and Cellular Endocrinology.
[15] P. Pandolfi,et al. Cytoplasmic PML function in TGF-β signalling , 2004, Nature.
[16] J. Flaws,et al. Ovarian follicle development requires Smad3. , 2004, Molecular endocrinology.
[17] H. Lankinen,et al. Immunoneutralization of Growth Differentiation Factor 9 Reveals It Partially Accounts for Mouse Oocyte Mitogenic Activity1 , 2004, Biology of reproduction.
[18] M. Matzuk,et al. Growth Differentiation Factor 9 Regulates Expression of the Bone Morphogenetic Protein Antagonist Gremlin* , 2004, Journal of Biological Chemistry.
[19] R. Gilchrist,et al. Oocyte-somatic cell interactions during follicle development in mammals. , 2004, Animal reproduction science.
[20] S. Shimasaki,et al. Functional and Molecular Characterization of Naturally Occurring Mutations in the Oocyte-secreted Factors Bone Morphogenetic Protein-15 and Growth and Differentiation Factor-9* , 2004, Journal of Biological Chemistry.
[21] M. Mullen,et al. Mutations in the Genes for Oocyte-Derived Growth Factors GDF9 and BMP15 Are Associated with Both Increased Ovulation Rate and Sterility in Cambridge and Belclare Sheep (Ovis aries)1 , 2004, Biology of reproduction.
[22] L. Attisano,et al. Regulation of the TGFβ signalling pathway by ubiquitin-mediated degradation , 2004, Oncogene.
[23] C. Klein,et al. Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5. , 2004, Molecular endocrinology.
[24] F. Otsuka,et al. The bone morphogenetic protein system in mammalian reproduction. , 2004, Endocrine reviews.
[25] Mark P. de Caestecker,et al. The transforming growth factor-beta superfamily of receptors. , 2004, Cytokine & growth factor reviews.
[26] P. G. Knight,et al. Local roles of TGF-beta superfamily members in the control of ovarian follicle development. , 2003, Animal reproduction science.
[27] M. Surani,et al. Specification of germ cell fate in mice. , 2003, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[28] J. Massagué,et al. Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus , 2003, Cell.
[29] W. Vale,et al. Cripto forms a complex with activin and type II activin receptors and can block activin signaling , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[30] R. Gilchrist,et al. Comparison of oocyte factors and transforming growth factor-β in the regulation of DNA synthesis in bovine granulosa cells , 2003, Molecular and Cellular Endocrinology.
[31] S. Shimasaki,et al. Reproductive Biology and Endocrinology Open Access the Spatiotemporal Expression Pattern of the Bone Morphogenetic Protein Family in Rat Ovary Cell Types during the Estrous Cycle , 2003 .
[32] U. Vitt,et al. Growth differentiation factor-9 induces Smad2 activation and inhibin B production in cultured human granulosa-luteal cells. , 2003, The Journal of clinical endocrinology and metabolism.
[33] F. Otsuka,et al. Molecular Basis of Bone Morphogenetic Protein-15 Signaling in Granulosa Cells* , 2003, The Journal of Biological Chemistry.
[34] R. Behringer,et al. Requirement of Bmpr1a for Müllerian duct regression during male sexual development , 2002, Nature Genetics.
[35] Martin M. Matzuk,et al. Intercellular Communication in the Mammalian Ovary: Oocytes Carry the Conversation , 2002, Science.
[36] F. Otsuka,et al. A negative feedback system between oocyte bone morphogenetic protein 15 and granulosa cell kit ligand: Its role in regulating granulosa cell mitosis , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[37] D. Fishman,et al. Localization of the activin signal transduction components in normal human ovarian follicles: implications for autocrine and paracrine signaling in the ovary. , 2002, The Journal of clinical endocrinology and metabolism.
[38] J. Strauss,et al. Growth differentiation factor-9 inhibits 3'5'-adenosine monophosphate-stimulated steroidogenesis in human granulosa and theca cells. , 2002, The Journal of clinical endocrinology and metabolism.
[39] M. Byrne,et al. Knockout of pentraxin 3, a downstream target of growth differentiation factor-9, causes female subfertility. , 2002, Molecular endocrinology.
[40] J. Juengel,et al. Bmp15 mutations and ovarian function , 2002, Molecular and Cellular Endocrinology.
[41] Jeffrey L. Wrana,et al. Signal Transduction by the TGF-β Superfamily , 2002, Science.
[42] C. Deng,et al. Smad 3 May Regulate Follicular Growth in the Mouse Ovary1 , 2002, Biology of reproduction.
[43] B. Campbell,et al. Effect of bone morphogenetic protein 2 (BMP2) on oestradiol and inhibin A production by sheep granulosa cells, and localization of BMP receptors in the ovary by immunohistochemistry. , 2002, Reproduction.
[44] T. Raivio,et al. Activation of the bone morphogenetic protein signaling pathway induces inhibin beta(B)-subunit mRNA and secreted inhibin B levels in cultured human granulosa-luteal cells. , 2002, The Journal of clinical endocrinology and metabolism.
[45] E. Baracat,et al. Aberrant expression of growth differentiation factor-9 in oocytes of women with polycystic ovary syndrome. , 2002, The Journal of clinical endocrinology and metabolism.
[46] J. Juengel,et al. Genetic mutations influencing ovulation rate in sheep. , 2001, Reproduction, fertility, and development.
[47] C. Heldin,et al. Smad regulation in TGF-beta signal transduction. , 2001, Journal of cell science.
[48] C. Deng,et al. Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion. , 2001, Developmental biology.
[49] J. Eppig,et al. Oocyte control of ovarian follicular development and function in mammals. , 2001, Reproduction.
[50] E. Robertson,et al. Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation. , 2001, Development.
[51] S. Shimasaki,et al. Biological Function and Cellular Mechanism of Bone Morphogenetic Protein-6 in the Ovary* , 2001, The Journal of Biological Chemistry.
[52] C. Heldin,et al. Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads , 2001, The EMBO journal.
[53] Yusuke Nakamura,et al. Axin Facilitates Smad3 Activation in the Transforming Growth Factor β Signaling Pathway , 2001, Molecular and Cellular Biology.
[54] X. Qi,et al. Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[55] B. Yoon,et al. The type I BMP receptor BmprIB is essential for female reproductive function , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[56] R. Fairman,et al. Formation of a Stable Heterodimer between Smad2 and Smad4* , 2001, The Journal of Biological Chemistry.
[57] J. Visser,et al. The serine/threonine transmembrane receptor ALK2 mediates Müllerian inhibiting substance signaling. , 2001, Molecular endocrinology.
[58] Xiang-Xi Xu,et al. The adaptor molecule Disabled‐2 links the transforming growth factor β receptors to the Smad pathway , 2001, The EMBO journal.
[59] M. Matzuk,et al. Smad5 is required for mouse primordial germ cell development , 2001, Mechanisms of Development.
[60] M. Matzuk,et al. Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function. , 2001, Molecular endocrinology.
[61] K. Ikeda,et al. Filamin Associates with Smads and Regulates Transforming Growth Factor-β Signaling* , 2001, The Journal of Biological Chemistry.
[62] K. Miyazono,et al. Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins. , 2001, Molecular biology of the cell.
[63] C. Heldin,et al. Phosphorylation of Smad7 at Ser-249 Does Not Interfere with Its Inhibitory Role in Transforming Growth Factor-β-dependent Signaling but Affects Smad7-dependent Transcriptional Activation* , 2001, The Journal of Biological Chemistry.
[64] Shin Yamamoto,et al. Bone Morphogenetic Protein-15 Inhibits Follicle-stimulating Hormone (FSH) Action by Suppressing FSH Receptor Expression* , 2001, The Journal of Biological Chemistry.
[65] Serhiy Souchelnytskyi,et al. Regulation of Smad signaling by protein kinase C , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[66] Benoy M. Chacko,et al. The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization , 2001, Nature Structural Biology.
[67] R. Weinberg,et al. Ski/Sno and TGF-β signaling , 2001 .
[68] R. Derynck,et al. Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[69] C. Hill,et al. Transforming Growth Factor β-Independent Shuttling of Smad4 between the Cytoplasm and Nucleus , 2000, Molecular and Cellular Biology.
[70] Xia Lin,et al. Smurf2 Is a Ubiquitin E3 Ligase Mediating Proteasome-dependent Degradation of Smad2 in Transforming Growth Factor-β Signaling* 210 , 2000, The Journal of Biological Chemistry.
[71] R. Mason,et al. Inactivation of Smad-Transforming Growth Factor β Signaling by Ca2+-Calmodulin-Dependent Protein Kinase II , 2000, Molecular and Cellular Biology.
[72] U. Vitt,et al. In vivo treatment with GDF-9 stimulates primordial and primary follicle progression and theca cell marker CYP17 in ovaries of immature rats. , 2000, Endocrinology.
[73] C. Klein,et al. Growth Differentiation Factor-9 Stimulates Rat Theca-Interstitial Cell Androgen Biosynthesis1 , 2000, Biology of reproduction.
[74] Y G Chen,et al. Engagement of bone morphogenetic protein type IB receptor and Smad1 signaling by anti-Müllerian hormone and its type II receptor. , 2000, The Journal of biological chemistry.
[75] E. Nishida,et al. Regulation of intracellular dynamics of Smad4 by its leucine‐rich nuclear export signal , 2000, EMBO reports.
[76] G. Montgomery,et al. Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner , 2000, Nature Genetics.
[77] K. Lewis,et al. Betaglycan binds inhibin and can mediate functional antagonism of activin signalling , 2000, Nature.
[78] M. Gimbrone,et al. A role for Smad6 in development and homeostasis of the cardiovascular system , 2000, Nature Genetics.
[79] U. Vitt,et al. Growth Differentiation Factor-9 Stimulates Proliferation but Suppresses the Follicle-Stimulating Hormone-Induced Differentiation of Cultured Granulosa Cells from Small Antral and Preovulatory Rat Follicles1 , 2000, Biology of reproduction.
[80] T. Shioda,et al. The Smad4 Activation Domain (SAD) Is a Proline-rich, p300-dependent Transcriptional Activation Domain* , 2000, The Journal of Biological Chemistry.
[81] K. Miyazono,et al. Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation. , 1999, Journal of cell science.
[82] Anita B. Roberts,et al. Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response , 1999, Nature Cell Biology.
[83] Jeffrey L. Wrana,et al. A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation , 1999, Nature.
[84] N. Ueno,et al. A functional bone morphogenetic protein system in the ovary. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[85] M. Matzuk,et al. Paracrine actions of growth differentiation factor-9 in the mammalian ovary. , 1999, Molecular endocrinology.
[86] E. Nishida,et al. Identification of Two Smad4 Proteins in Xenopus , 1999, The Journal of Biological Chemistry.
[87] M. Matzuk,et al. Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects. , 1999, Development.
[88] J. Massagué,et al. A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras. , 1999, Genes & development.
[89] J. D. Brown,et al. MEKK-1, a Component of the Stress (Stress-activated Protein Kinase/c-Jun N-terminal Kinase) Pathway, Can Selectively Activate Smad2-mediated Transcriptional Activation in Endothelial Cells* , 1999, The Journal of Biological Chemistry.
[90] U. M. Rose,et al. Recombinant Growth Differentiation Factor-9 (GDF-9) Enhances Growth and Differentiation of Cultured Early Ovarian Follicles. , 1999, Endocrinology.
[91] A. Roberts,et al. Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF‐β , 1999, The EMBO journal.
[92] J. Gauthier,et al. A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3 , 1999, Oncogene.
[93] Liliana Attisano,et al. SARA, a FYVE Domain Protein that Recruits Smad2 to the TGFβ Receptor , 1998, Cell.
[94] M. Matzuk,et al. The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes. , 1998, Molecular endocrinology.
[95] E. Lehtonen,et al. A novel growth differentiation factor-9 (GDF-9) related factor is co-expressed with GDF-9 in mouse oocytes during folliculogenesis , 1998, Mechanisms of Development.
[96] C. Heldin,et al. Transforming Growth Factor β1 Induces Nuclear Export of Inhibitory Smad7* , 1998, The Journal of Biological Chemistry.
[97] P. Hoodless,et al. Specific Activation of Smad1 Signaling Pathways by the BMP7 Type I Receptor, ALK2* , 1998, The Journal of Biological Chemistry.
[98] J. Graff,et al. Smad3 Mutant Mice Develop Metastatic Colorectal Cancer , 1998, Cell.
[99] C. Heldin,et al. The L45 loop in type I receptors for TGF‐β family members is a critical determinant in specifying Smad isoform activation , 1998, FEBS letters.
[100] C. Deng,et al. Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[101] J. Massagué,et al. Determinants of specificity in TGF-beta signal transduction. , 1998, Genes & development.
[102] E. Li,et al. Smad2 role in mesoderm formation, left–right patterning and craniofacial development , 1998, Nature.
[103] M. Kretzschmar,et al. Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1 , 1997, Nature.
[104] J. Massagué,et al. Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4 , 1997, Nature.
[105] V. Rosen,et al. Identification of ovarian granulosa cells as a novel site of expression for bone morphogenetic protein-3 (BMP-3/osteogenin) and regulation of BMP-3 messenger ribonucleic acids by chorionic gonadotropin in cultured human granulosa-luteal cells. , 1996, The Journal of clinical endocrinology and metabolism.
[106] B. Vogelstein,et al. Nomenclature: Vertebrate Mediators of TGFβ Family Signals , 1996, Cell.
[107] David F. Albertini,et al. Growth differentiation factor-9 is required during early ovarian folliculogenesis , 1996, Nature.
[108] A. Gougeon. Regulation of ovarian follicular development in primates: facts and hypotheses. , 1996, Endocrine reviews.
[109] K. Miyazono,et al. Cloning and characterization of a human type II receptor for bone morphogenetic proteins. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[110] M. Benahmed,et al. Ovary: Immunolocalization of transforming growth factor-β1 and transforming growth factor-β2 in the mouse ovary during gonadotrophin-induced follicular maturation , 1995 .
[111] J. Smith,et al. Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects , 1995, The Journal of cell biology.
[112] J. Sekelsky,et al. Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. , 1995, Genetics.
[113] K. Lyons,et al. A mammalian serine/threonine kinase receptor specifically binds BMP-2 and BMP-4. , 1994, Biochemical and biophysical research communications.
[114] D. Riddle,et al. Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4. , 1994, The Journal of biological chemistry.
[115] P. Schmid,et al. Expression of TGF-βS and TGF-β Type II Receptor mRNAs in Mouse Folliculogenesis: Stored Maternal TGF-β2 Message in Oocytes , 1994 .
[116] K. Miyazono,et al. Characterization of type I receptors for transforming growth factor-beta and activin. , 1994, Science.
[117] D. Robertson,et al. Effects of activin and follicle-stimulating hormone (FSH)-suppressing protein/follistatin on FSH receptors and differentiation of cultured rat granulosa cells. , 1992, Endocrinology.
[118] R. Weinberg,et al. Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase , 1992, Cell.
[119] J. Massagué,et al. Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors , 1992, Cell.
[120] L. Mathews,et al. Expression cloning of an activin receptor, a predicted transmembrane serine kinase , 1991, Cell.
[121] J. Rabinovici,et al. Recombinant human activin-A promotes proliferation of human luteinized preovulatory granulosa cells in vitro. , 1990, The Journal of clinical endocrinology and metabolism.
[122] B. Hogan,et al. Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development. , 1989, Genes & development.
[123] R. Gilchrist,et al. Adenoviral gene transfer allows Smad-responsive gene promoter analyses and delineation of type I receptor usage of transforming growth factor-beta family ligands in cultured human granulosa luteal cells. , 2005, The Journal of clinical endocrinology and metabolism.
[124] Chad H. Koonce,et al. Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile. , 2005, Genes & development.
[125] Pier Paolo Pandolfi,et al. Cytoplasmic PML function in TGF-beta signalling. , 2004, Nature.
[126] M. D. de Caestecker,et al. The transforming growth factor-beta superfamily of receptors. , 2004, Cytokine & growth factor reviews.
[127] A. Hsueh,et al. Growth differentiation factor-9 stimulates inhibin production and activates Smad2 in cultured rat granulosa cells. , 2003, Endocrinology.
[128] R. Derynck,et al. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. , 2003, Nature.
[129] J. Wrana,et al. Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover. , 2003, Nature cell biology.
[130] J. Massagué,et al. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. , 2003, Cell.
[131] J. Wrana,et al. Signal transduction by the TGF-beta superfamily. , 2002, Science.
[132] A. Durlinger,et al. Anti-Müllerian hormone inhibits initiation of primordial follicle growth in the mouse ovary. , 2002, Endocrinology.
[133] K. Mayo,et al. Gonadal pathologies in transgenic mice expressing the rat inhibin alpha-subunit. , 2001, Endocrinology.
[134] R. Weinberg,et al. Ski/Sno and TGF-beta signaling. , 2001, Cytokine & growth factor reviews.
[135] N. Spears,et al. Müllerian Inhibitory Substance Induces Growth of Rat Preantral Ovarian Follicles1 , 2001, Biology of reproduction.
[136] R. Rey,et al. Ovarian granulosa cell tumors express a functional membrane receptor for anti-Müllerian hormone in transgenic mice. , 2001, Endocrinology.
[137] P. Goldschmidt-Clermont,et al. Microtubule binding to Smads may regulate TGF beta activity. , 2000, Molecular cell.
[138] J. Massagué. How cells read TGF-beta signals. , 2000, Nature reviews. Molecular cell biology.
[139] Xin-Hua Feng,et al. Microtubule Binding to Smads May Regulate TGFβ Activity , 2000 .
[140] A. Durlinger,et al. Printed in U.S.A. Copyright © 1999 by The Endocrine Society Control of Primordial Follicle Recruitment by Anti-Müllerian Hormone in the Mouse Ovary* , 2022 .
[141] C. Niehrs,et al. Silencing of TGF-beta signalling by the pseudoreceptor BAMBI. , 1999, Nature.
[142] J. Rossant,et al. The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo. , 1998, Genes & development.
[143] P. Hoodless,et al. Specific Activation of Smad 1 Signaling Pathways by the BMP 7 Type I Receptor , ALK 2 * , 1998 .
[144] B. Vogelstein,et al. Nomenclature: vertebrate mediators of TGFbeta family signals. , 1996, Cell.
[145] M. Benahmed,et al. Immunolocalization of transforming growth factor-beta 1 and transforming growth factor-beta 2 in the mouse ovary during gonadotrophin-induced follicular maturation. , 1995, Human reproduction.
[146] S. McGrath,et al. Oocyte-specific expression of growth/differentiation factor-9. , 1995, Molecular endocrinology.
[147] L. Wilming,et al. A novel member of the transmembrane serine/threonine kinase receptor family is specifically expressed in the gonads and in mesenchymal cells adjacent to the müllerian duct. , 1994, Development.
[148] P. Schmid,et al. Expression of TGF-beta s and TGF-beta type II receptor mRNAs in mouse folliculogenesis: stored maternal TGF-beta 2 message in oocytes. , 1994, Biochemical and biophysical research communications.
[149] Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase. , 1992, Cell.