Direct costs of chronic obstructive pulmonary disease among managed care patients

Purpose To estimate patient- and episode-level direct costs of chronic obstructive pulmonary disease (COPD) among commercially insured patients in the US. Methods In this retrospective claims-based analysis, commercial enrollees with evidence of COPD were grouped into five mutually exclusive cohorts based on the most intensive level of COPD-related care they received in 2006, ie, outpatient, urgent outpatient (outpatient care in addition to a claim for an oral corticosteroid or antibiotic within seven days), emergency department (ED), standard inpatient admission, and intensive care unit (ICU) cohorts. Patient- level COPD-related annual health care costs, including patient- and payer-paid costs, were compared among the cohorts. Adjusted episode-level costs were calculated. Results Of the 37,089 COPD patients included in the study, 53% were in the outpatient cohort, 37% were in the urgent outpatient cohort, 3% were in the ED cohort, and the standard admission and ICU cohorts together comprised 6%. Mean (standard deviation, SD) annual COPD-related health care costs (2008 US$) increased across the cohorts (P < 0.001), ranging from $2003 ($3238) to $43,461 ($76,159) per patient. Medical costs comprised 96% of health care costs for the ICU cohort. Adjusted mean (SD) episode-level costs were $305 ($310) for an outpatient visit, $274 ($336) for an urgent outpatient visit, $327 ($65) for an ED visit, $9745 ($2968) for a standard admission, and $33,440 for an ICU stay. Conclusion Direct costs of COPD-related care for commercially insured patients are driven by hospital stays with or without ICU care. Exacerbation prevention resulting in reduced need for inpatient care could lower costs.

[1]  Anand A. Dalal,et al.  Costs of COPD exacerbations in the emergency department and inpatient setting. , 2011, Respiratory medicine.

[2]  D. Lauderdale,et al.  Hospitalizations for Acute Exacerbations of Chronic Obstructive Pulmonary Disease: How You Count Matters , 2010, COPD.

[3]  A. Anzueto,et al.  Dovepress Open Access to Scientific and Medical Research Open Access Full Text Article Impact of Frequency of Copd Exacerbations on Pulmonary Function, Health Status and Clinical Outcomes , 2022 .

[4]  I. Adcock,et al.  Clinical Definition of COPD Exacerbations and Classification of Their Severity , 2009, Southern medical journal.

[5]  U. Gerdtham,et al.  Factors affecting chronic obstructive pulmonary disease (COPD)-related costs: a multivariate analysis of a Swedish COPD cohort , 2009, The European Journal of Health Economics.

[6]  E. Geelhoed,et al.  Reduction in hospitalisation following pulmonary rehabilitation in patients with COPD. , 2008, Australian health review : a publication of the Australian Hospital Association.

[7]  M. Miravitlles,et al.  Exacerbations worsen the quality of life of chronic obstructive pulmonary disease patients in primary healthcare , 2008, International journal of clinical practice.

[8]  L. Kuramoto,et al.  The cost of moderate and severe COPD exacerbations to the Canadian healthcare system. , 2008, Respiratory medicine.

[9]  T. Seemungal,et al.  Investigating New Standards for Prophylaxis in Reduction of Exacerbations—The INSPIRE Study Methodology , 2007, COPD.

[10]  C. Mathers,et al.  Projections of Global Mortality and Burden of Disease from 2002 to 2030 , 2006, PLoS medicine.

[11]  C. D. Mathers,et al.  Chronic obstructive pulmonary disease: current burden and future projections , 2006, European Respiratory Journal.

[12]  R. Stanford,et al.  Cost of Chronic Obstructive Pulmonary Disease in the Emergency Department and Hospital , 2006, Treatments in respiratory medicine.

[13]  H. Quan,et al.  Coding Algorithms for Defining Comorbidities in ICD-9-CM and ICD-10 Administrative Data , 2005, Medical care.

[14]  W. MacNee,et al.  Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper , 2004, European Respiratory Journal.

[15]  Chronic obstructive pulmonary disease. National clinical guideline on management of chronic obstructive pulmonary disease in adults in primary and secondary care. , 2004, Thorax.

[16]  D. Forman,et al.  Delays in managing lung cancer. , 2004, Thorax.

[17]  T. Seemungal,et al.  Longitudinal changes in the nature, severity and frequency of COPD exacerbations , 2003, European Respiratory Journal.

[18]  M. Halpern,et al.  The burden of COPD in the U.S.A.: results from the Confronting COPD survey. , 2003, Respiratory medicine.

[19]  E. Wouters Economic analysis of the Confronting COPD survey: an overview of results. , 2003, Respiratory medicine.

[20]  S. Borg,et al.  Costs of COPD in Sweden according to disease severity. , 2002, Chest.

[21]  E. Rönmark,et al.  The costs of exacerbations in chronic obstructive pulmonary disease (COPD). , 2002, Respiratory medicine.

[22]  D. Mannino,et al.  Chronic obstructive pulmonary disease surveillance--United States, 1971-2000. , 2002, Morbidity and mortality weekly report. Surveillance summaries.

[23]  R. Pauwels,et al.  Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: National Heart, Lung, and Blood Institute and World Health Organization Global Initiative for Chronic Obstructive Lung Disease (GOLD): executive summary. , 2001, Respiratory care.

[24]  W. Manning,et al.  The logged dependent variable, heteroscedasticity, and the retransformation problem. , 1998, Journal of health economics.

[25]  Injury rates by industry 1970, BLS Report 406, Department of Labor, Bureau of Labor Statistics. , 1972, IMS, Industrial medicine and surgery.