Rinat Sergeev Drug-Resistant Tuberculosis Modeling the Dynamic Relationship Between HIV and the Risk of

that longitudinal studies, not a snapshot, will provide a better picture of the whole evolving story. . suggest et al perhaps as a result of less stringent selective pressure. Thus, Sergeev −− HIV-seronegative populations drug-resistant TB in HIV-seropositive populations may actually be less fit than drug-resistant TB that develops in rare. Intriguingly, although HIV infection may increase the prevalence of drug-resistant TB within a population, infections, acquired at a time when drug-resistant TB was M. Tb explained by HIV-stimulated reactivation of latent developing drug-resistant TB at the early stages of the coepidemic. Although counterintuitive, these results may be infections within a community over several decades, HIV-infected individuals may actually be at lower relative risk of drug-resistant TB. They found that, whereas HIV infection facilitated the rise in numbers of drug-resistant TB The authors developed a mathematical model to explore the effect of HIV on the dynamics of emerging drug-resistant TB. . provide a dynamic look at the relationship between HIV infection and the risk of acquiring et al results. Now, Sergeev developing drug-resistant TB. However, different studies of HIV-infected individuals with TB have yielded conflicting tuberculosis (TB). Some researchers have suggested that HIV-infected populations are more susceptible to can help, but inconsistencies may remain. Such is the case for the epidemiological interactions of HIV and A picture may be worth a thousand words, but a snapshot only gives you part of the story. Comparing snapshots Only Time Will Tell