Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases
暂无分享,去创建一个
J. Sydor | T. Terasaki | G. Fricker | Loic Laplanche | Yasuo Uchida | J. Delzer | M. Tachikawa | Yutaro Hoshi | Dominik Gartzke
[1] G. Fricker,et al. Establishment of optimized MDCK cell lines for reliable efflux transport studies. , 2014, Journal of pharmaceutical sciences.
[2] D. Richardson,et al. P-glycoprotein Mediates Drug Resistance via a Novel Mechanism Involving Lysosomal Sequestration* , 2013, The Journal of Biological Chemistry.
[3] T. Terasaki,et al. Quantitative atlas of blood-brain barrier transporters, receptors, and tight junction proteins in rats and common marmoset. , 2013, Journal of pharmaceutical sciences.
[4] T. Terasaki,et al. A study protocol for quantitative targeted absolute proteomics (QTAP) by LC-MS/MS: application for inter-strain differences in protein expression levels of transporters, receptors, claudin-5, and marker proteins at the blood–brain barrier in ddY, FVB, and C57BL/6J mice , 2013, Fluids and Barriers of the CNS.
[5] Michael P. Snyder,et al. Extensive genetic variation in somatic human tissues , 2012, Proceedings of the National Academy of Sciences.
[6] G. Hausner,et al. Homing endonucleases: DNA scissors on a mission. , 2012, Genome.
[7] J. Dukes,et al. The MDCK variety pack: choosing the right strain , 2011, BMC Cell Biology.
[8] T. Terasaki,et al. Quantitative membrane protein expression at the blood-brain barrier of adult and younger cynomolgus monkeys. , 2011, Journal of pharmaceutical sciences.
[9] C. Daumas-Duport,et al. Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels. , 2011, Molecular pharmaceutics.
[10] Takashi Suzuki,et al. Quantitative targeted absolute proteomics of human blood–brain barrier transporters and receptors , 2011, Journal of neurochemistry.
[11] Wolfgang Löscher,et al. Differences in the expression of endogenous efflux transporters in MDR1‐transfected versus wildtype cell lines affect P‐glycoprotein mediated drug transport , 2010, British journal of pharmacology.
[12] M. Niemi,et al. Membrane transporters in drug development , 2010, Nature Reviews Drug Discovery.
[13] Y. Sugiyama,et al. Model Analysis of the Concentration-Dependent Permeability of P-gp Substrates , 2010, Pharmaceutical Research.
[14] G. Chakravarty,et al. Montelukast is a potent and durable inhibitor of multidrug resistance protein 2-mediated efflux of taxol and saquinavir. , 2009, Biological & pharmaceutical bulletin.
[15] J. Lupski,et al. Mechanisms of change in gene copy number , 2009, Nature Reviews Genetics.
[16] I. Romero,et al. P-Glycoprotein and Breast Cancer Resistance Protein Restrict Apical-to-Basolateral Permeability of Human Brain Endothelium to Amyloid-β , 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[17] N. Simmons,et al. Induction of P-glycoprotein expression and function in human intestinal epithelial cells (T84). , 2008, Biochemical pharmacology.
[18] Bo Feng,et al. In Vitro P-glycoprotein Assays to Predict the in Vivo Interactions of P-glycoprotein with Drugs in the Central Nervous System , 2008, Drug Metabolism and Disposition.
[19] Tetsuya Terasaki,et al. Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria , 2008, Pharmaceutical Research.
[20] Jos H Beijnen,et al. P-Glycoprotein and Breast Cancer Resistance Protein: Two Dominant Transporters Working Together in Limiting the Brain Penetration of Topotecan , 2007, Clinical Cancer Research.
[21] Scott E. Martin,et al. Applications of RNA interference in mammalian systems. , 2007, Annual review of genomics and human genetics.
[22] Fyodor D Urnov,et al. Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases , 2007, Proceedings of the National Academy of Sciences.
[23] Supratim Choudhuri,et al. Structure, Function, Expression, Genomic Organization, and Single Nucleotide Polymorphisms of Human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) Efflux Transporters , 2006, International journal of toxicology.
[24] C. Glaubitz,et al. Localization of multidrug transporter substrates within model membranes. , 2006, Biochemistry.
[25] J. Keogh,et al. Development, validation and utility of an in vitro technique for assessment of potential clinical drug-drug interactions involving P-glycoprotein. , 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[26] M. Bibikova,et al. Efficient Gene Targeting in Drosophila With Zinc-Finger Nucleases , 2006, Genetics.
[27] M. Gottesman,et al. Targeting multidrug resistance in cancer , 2006, Nature Reviews Drug Discovery.
[28] Andrew D. Johnson,et al. Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability , 2005, Pharmacogenetics and genomics.
[29] Jeffrey C. Miller,et al. Highly efficient endogenous human gene correction using designed zinc-finger nucleases , 2005, Nature.
[30] N. Shibata,et al. In vivo effects of cyclosporin A and ketoconazole on the pharmacokinetics of representative substrates for P-glycoprotein and cytochrome P450 (CYP) 3A in rats. , 2005, Biological & pharmaceutical bulletin.
[31] R. Evers,et al. Eletriptan metabolism by human hepatic CYP450 enzymes and transport by human P-glycoprotein. , 2003, Drug metabolism and disposition: the biological fate of chemicals.
[32] David Baltimore,et al. Chimeric Nucleases Stimulate Gene Targeting in Human Cells , 2003, Science.
[33] Dana Carroll,et al. Enhancing Gene Targeting with Designed Zinc Finger Nucleases , 2003, Science.
[34] T. Friedberg,et al. Endogenous drug transporters in in vitro and in vivo models for the prediction of drug disposition in man. , 2002, Biochemical pharmacology.
[35] L. Faivre,et al. Effect of interleukin-2 on intestinal P-glycoprotein expression and functionality in mice. , 2002, The Journal of pharmacology and experimental therapeutics.
[36] J. Polli,et al. Rational use of in vitro P-glycoprotein assays in drug discovery. , 2001, The Journal of pharmacology and experimental therapeutics.
[37] A. Aggarwal,et al. FokI requires two specific DNA sites for cleavage. , 2001, Journal of molecular biology.
[38] J. Hochman,et al. In vitro substrate identification studies for p-glycoprotein-mediated transport: species difference and predictability of in vivo results. , 2001, The Journal of pharmacology and experimental therapeutics.
[39] B. Rothen‐Rutishauser,et al. Cell cultures as tools in biopharmacy. , 2000, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[40] S Chandrasegaran,et al. Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains. , 2000, Nucleic acids research.
[41] J. Bitinaite,et al. FokI dimerization is required for DNA cleavage. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[42] S Chandrasegaran,et al. Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[43] A Klug,et al. Zinc fingers , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[44] Carol L. Williams,et al. Transepithelial transport of drugs by the multidrug transporter in cultured Madin-Darby canine kidney cell epithelia. , 1989, The Journal of biological chemistry.
[45] I. Pastan,et al. A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[46] M. Terzi. Chromosomal variation and the origin of drug-resistant mutants in mammalian cell lines. , 1974, Proceedings of the National Academy of Sciences of the United States of America.
[47] Springer Basel. Gene knockout and knockin by zinc-finger nucleases: current status and perspectives , 2012 .
[48] M. Pomper,et al. Hedgehog pathway inhibitor HhAntag691 is a potent inhibitor of ABCG2/BCRP and ABCB1/Pgp. , 2009, Neoplasia.
[49] Thomas J. Vidmar,et al. The Madin Darby Canine Kidney (MDCK) Epithelial Cell Monolayer as a Model Cellular Transport Barrier , 2004, Pharmaceutical Research.
[50] S Chandrasegaran,et al. A detailed study of the substrate specificity of a chimeric restriction enzyme. , 1999, Nucleic acids research.
[51] J. Tolan,et al. MDCK (Madin-Darby canine kidney) cells: A tool for membrane permeability screening. , 1999, Journal of pharmaceutical sciences.
[52] J. Silverman. Multidrug-resistance transporters. , 1999, Pharmaceutical biotechnology.