OpenPrescribing: normalised data and software tool to research trends in English NHS primary care prescribing 1998–2016

Objectives We aimed to compile and normalise England’s national prescribing data for 1998–2016 to facilitate research on long-term time trends and create an open-data exploration tool for wider use. Design We compiled data from each individual year’s national statistical publications and normalised them by mapping each drug to its current classification within the national formulary where possible. We created a freely accessible, interactive web tool to allow anyone to interact with the processed data. Setting and participants We downloaded all available annual prescription cost analysis datasets, which include cost and quantity for all prescription items dispensed in the community in England. Medical devices and appliances were excluded. Primary and secondary outcome measures We measured the extent of normalisation of data and aimed to produce a functioning accessible analysis tool. Results All data were imported successfully. 87.5% of drugs were matched exactly on name to the current formulary and a further 6.5% to similar drug names. All drugs in core clinical chapters were reconciled to their current location in the data schema, with only 1.26% of drugs not assigned a current chemical code. We created an openly accessible interactive tool to facilitate wider use of these data. Conclusions Publicly available data can be made accessible through interactive online tools to help researchers and policy-makers explore time trends in prescribing.

[1]  R. Afshari,et al.  Effects of licence change on prescribing and poisons enquiries for antipsychotic agents in England and Scotland. , 2003, British journal of clinical pharmacology.

[2]  Manuela Lippek National Health Service (NHS) in England , 2004 .

[3]  S. Pearce,et al.  Trends in thyroid hormone prescribing and consumption in the UK , 2009, BMC public health.

[4]  E. Dietrich Effects of the National Institute for Health and Clinical Excellence's technology appraisals on prescribing and net ingredient costs of drugs in the National Health Service in England , 2009, International Journal of Technology Assessment in Health Care.

[5]  T. Coleman,et al.  Prescribing of smoking cessation medication in England since the introduction of varenicline. , 2011, Addiction.

[6]  T. Coleman,et al.  The impact of the introduction of smoke-free legislation on prescribing of stop-smoking medications in England. , 2011, Addiction.

[7]  J. Moncrieff,et al.  Trends in prescriptions and costs of drugs for mental disorders in England, 1998-2010. , 2012, The British journal of psychiatry : the journal of mental science.

[8]  M. May,et al.  Effects of MHRA drug safety advice on time trends in prescribing volume and indices of clinical toxicity for quinine. , 2013, British journal of clinical pharmacology.

[9]  R. Quinton,et al.  A UK epidemic of testosterone prescribing, 2001–2010 , 2013, Clinical endocrinology.

[10]  A. Connor,et al.  Glaucoma prescribing trends in England 2000 to 2012 , 2014, Eye.

[11]  R. Fitzpatrick,et al.  Assessing the impact of NICE guidance on the prescribing of hormonal treatments of breast cancer in England. , 2015, Journal of evaluation in clinical practice.

[12]  P. Aveyard,et al.  Provision of smoking cessation support in UK primary care: impact of the 2012 QOF revision. , 2016, The British journal of general practice : the journal of the Royal College of General Practitioners.