CRISPR-Cas9 editing of TLR4 to improve the outcome of cardiac cell therapy
暂无分享,去创建一个
J. Leor | N. Naftali-Shani | E. Raanani | L. Sternik | Y. Schary | R. Brzezinski | N. Lewis | I. Rotem | D. Lendengolts | O. Shaihov–Teper | T. Caller
[1] J. Leor,et al. Osteopontin promotes infarct repair , 2022, Basic Research in Cardiology.
[2] R. Bassel-Duby,et al. Toward CRISPR Therapies for Cardiomyopathies , 2021, Circulation.
[3] A. Brazma,et al. The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences , 2021, Nucleic Acids Res..
[4] N. Karrow,et al. CRISPR-Cas9-mediated knockout of TLR4 modulates Mycobacterium avium ssp. paratuberculosis cell lysate-induced inflammation in bovine mammary epithelial cells. , 2021, Journal of dairy science.
[5] S. Prabhu,et al. Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure , 2021, JACC. Basic to translational science.
[6] J. Leor,et al. Extracellular Vesicles From Epicardial Fat Facilitate Atrial Fibrillation , 2021, Circulation.
[7] P. Doevendans,et al. Damage-Associated Molecular Patterns in Myocardial Infarction and Heart Transplantation: The Road to Translational Success , 2020, Frontiers in Immunology.
[8] Nadezhda T. Doncheva,et al. The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets , 2020, Nucleic Acids Res..
[9] K. Kwiatkowska,et al. TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling , 2020, Cellular and Molecular Life Sciences.
[10] R. Bolli,et al. Administration of cardiac mesenchymal cells modulates innate immunity in the acute phase of myocardial infarction in mice , 2020, Scientific Reports.
[11] V. Ezenwa,et al. Complex Tissue Regeneration in Mammals Is Associated With Reduced Inflammatory Cytokines and an Influx of T Cells , 2020, Frontiers in Immunology.
[12] Yun Wang,et al. Adipose mesenchymal stem cell-derived extracellular vesicles containing microRNA-26a-5p target TLR4 and protect against diabetic nephropathy , 2020, The Journal of Biological Chemistry.
[13] Shijun Hu,et al. The therapeutic potential of mesenchymal stem cells for cardiovascular diseases , 2020, Cell Death & Disease.
[14] Lei S. Qi,et al. Therapeutic genome editing in cardiovascular diseases. , 2020, Advanced drug delivery reviews.
[15] M. Pittenger,et al. Mesenchymal stem cell perspective: cell biology to clinical progress , 2019, npj Regenerative Medicine.
[16] J. Molkentin,et al. An acute immune response underlies the benefit of cardiac stem cell therapy , 2019, Nature.
[17] F. Spinale,et al. Heart failure as interstitial cancer: emergence of a malignant fibroblast phenotype , 2019, Nature Reviews Cardiology.
[18] N. Frangogiannis. How do endosomal Toll-like Receptors (TLRs) sense and extend ischemic myocardial injury? , 2019, Cardiovascular research.
[19] L. Kirshenbaum,et al. Inflammation in myocardial injury- mesenchymal stem cells as potential immunomodulators. , 2019, American journal of physiology. Heart and circulatory physiology.
[20] J. Downey,et al. Innate immunity as a target for acute cardioprotection. , 2019, Cardiovascular research.
[21] N. Frangogiannis,et al. Fibroblasts in the Infarcted, Remodeling, and Failing Heart , 2019, JACC. Basic to translational science.
[22] D. Funamoto,et al. Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice. , 2019, Cardiovascular research.
[23] S. Hoerstrup,et al. Proteomic analysis of human mesenchymal stromal cell secretomes: a systematic comparison of the angiogenic potential , 2019, npj Regenerative Medicine.
[24] F. Granucci,et al. Below the surface: The inner lives of TLR4 and TLR9 , 2019, Journal of leukocyte biology.
[25] Jing Xu,et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines , 2018, Journal of Extracellular Vesicles.
[26] Damian Szklarczyk,et al. STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets , 2018, Nucleic Acids Res..
[27] M. Packer. The Alchemist’s Nightmare: Might Mesenchymal Stem Cells That Are Recruited to Repair the Injured Heart Be Transformed Into Fibroblasts Rather Than Cardiomyocytes? , 2018, Circulation.
[28] J. Molkentin,et al. Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart , 2018, The Journal of clinical investigation.
[29] X. Cui,et al. Concise Review: Is Cardiac Cell Therapy Dead? Embarrassing Trial Outcomes and New Directions for the Future , 2018, Stem cells translational medicine.
[30] Hongliang Li,et al. Insights into innate immune signalling in controlling cardiac remodelling. , 2017, Cardiovascular research.
[31] A. Scharenberg,et al. Therapeutic Gene Editing Safety and Specificity. , 2017, Hematology/oncology clinics of North America.
[32] M. V. Goncharuk,et al. Spatial structure of TLR4 transmembrane domain in bicelles provides the insight into the receptor activation mechanism , 2017, Scientific Reports.
[33] J. Leor,et al. Left Ventricular Dysfunction Switches Mesenchymal Stromal Cells Toward an Inflammatory Phenotype and Impairs Their Reparative Properties Via Toll-Like Receptor-4 , 2017, Circulation.
[34] J. Molkentin,et al. Redefining the identity of cardiac fibroblasts , 2017, Nature Reviews Cardiology.
[35] Yu-Kyoung Oh,et al. Therapeutic gene editing: delivery and regulatory perspectives , 2017, Acta Pharmacologica Sinica.
[36] M. Porteus,et al. Genome Editing in Cardiovascular Biology , 2017, Circulation research.
[37] J. Leor,et al. Loss of Macrophage Wnt Secretion Improves Remodeling and Function After Myocardial Infarction in Mice , 2017, Journal of the American Heart Association.
[38] R. Califf,et al. Clarifying Stem-Cell Therapy's Benefits and Risks. , 2016, The New England journal of medicine.
[39] Yue Tang,et al. Bone Marrow Mesenchymal Stem Cells (BM-MSCs) Improve Heart Function in Swine Myocardial Infarction Model through Paracrine Effects , 2016, Scientific Reports.
[40] K. Patel,et al. Paracrine effects of TLR4-polarised mesenchymal stromal cells are mediated by extracellular vesicles , 2016, Journal of Translational Medicine.
[41] D. Gattas,et al. SEPSIS-INDUCED MYOCARDIAL DEPRESSION IS ASSOCIATED WITH APOPTOSIS AND DIFFERENTIAL REGULATION OF S100A1, S100B, AND S100A6 AND THEIR RECEPTORS, RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS AND TOLL-LIKE RECEPTOR 4 , 2015 .
[42] D. Widera,et al. Controversial Role of Toll-like Receptor 4 in Adult Stem Cells , 2015, Stem Cell Reviews and Reports.
[43] Sky W. Brubaker,et al. Innate immune pattern recognition: a cell biological perspective. , 2015, Annual review of immunology.
[44] B. van Steensel,et al. Easy quantitative assessment of genome editing by sequence trace decomposition , 2014, Nucleic acids research.
[45] E. Eggenhofer,et al. The Life and Fate of Mesenchymal Stem Cells , 2014, Front. Immunol..
[46] Jae Young Kim,et al. Anti-CD14 antibody reduces LPS responsiveness via TLR4 internalization in human monocytes. , 2014, Molecular immunology.
[47] J. Sluijter,et al. Mesenchymal Stem Cell Therapy for Cardiac Inflammation: Immunomodulatory Properties and the Influence of Toll-Like Receptors , 2013, Mediators of inflammation.
[48] J. Leor,et al. Macrophage subpopulations are essential for infarct repair with and without stem cell therapy. , 2013, Journal of the American College of Cardiology.
[49] W. Fibbe,et al. Mesenchymal stromal cells: sensors and switchers of inflammation. , 2013, Cell stem cell.
[50] M. Pevsner-Fischer,et al. The Origin of Human Mesenchymal Stromal Cells Dictates Their Reparative Properties , 2013, Journal of the American Heart Association.
[51] Le Cong,et al. Multiplex Genome Engineering Using CRISPR/Cas Systems , 2013, Science.
[52] N. Baldini,et al. Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy , 2012, Front. Physio..
[53] Kevin W Eliceiri,et al. NIH Image to ImageJ: 25 years of image analysis , 2012, Nature Methods.
[54] N. S. Asli,et al. Adult cardiac-resident MSC-like stem cells with a proepicardial origin. , 2011, Cell stem cell.
[55] J. Hare,et al. Mesenchymal stem cells: biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease. , 2011, Circulation research.
[56] D. Meldrum,et al. TLR4 Inhibits Mesenchymal Stem Cell (MSC) STAT3 Activation and Thereby Exerts Deleterious Effects on MSC–Mediated Cardioprotection , 2010, PloS one.
[57] Ruth S. Waterman,et al. A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype , 2010, PloS one.
[58] C. Tschöpe,et al. Toll-Like Receptor-4 Modulates Survival by Induction of Left Ventricular Remodeling after Myocardial Infarction in Mice1 , 2008, The Journal of Immunology.
[59] M. Goumans,et al. Toll-Like Receptor 4 Mediates Maladaptive Left Ventricular Remodeling and Impairs Cardiac Function After Myocardial Infarction , 2008, Circulation research.
[60] L. Cosmi,et al. Toll‐Like Receptors 3 and 4 Are Expressed by Human Bone Marrow‐Derived Mesenchymal Stem Cells and Can Inhibit Their T‐Cell Modulatory Activity by Impairing Notch Signaling , 2008, Stem cells.
[61] J. Leor,et al. Iron-Oxide Labeling and Outcome of Transplanted Mesenchymal Stem Cells in the Infarcted Myocardium , 2007, Circulation.
[62] C. Liang,et al. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro , 2007, Nature Protocols.
[63] Y. Bae,et al. Role of Toll‐Like Receptors on Human Adipose‐Derived Stromal Cells , 2006, Stem cells.
[64] J. Weiss. Faculty Opinions recommendation of Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: evidence for an intracellular compartmentalization of TLR4. , 2004 .
[65] Y. Saga,et al. Interleukin-10-mediated inhibition of angiogenesis and tumor growth in mice bearing VEGF-producing ovarian cancer. , 2003, Cancer research.
[66] R. Munford,et al. CD14-dependent internalization of bacterial lipopolysaccharide (LPS) is strongly influenced by LPS aggregation but not by cellular responses to LPS. , 1998, Journal of immunology.