Sensitivity and Specificity of the Finger Tapping Task for the Detection of Psychogenic Movement Disorders Recommended Citation Sensitivity and Specificity of the Finger Tapping Task for the Detection of Psychogenic Movement Disorders

Psychogenic movement disorders (PMD) represent a diagnostically challenging group of patients in movement disorders. Finger tapping tests (FTT) have been used in neuropsychiatric evaluations to identify psychogenic conditions, but their use in movement disorders has been limited to the quantification of upper extremity disability in idiopathic Parkinson disease (IPD). We evaluated the ability of the FTT to objectively identify PMD by screening 195 individuals from a movement disorder clinic with IPD, dystonia, essential tremor, or PMD and compared them to 130 normal adults. All subjects performed six-30 s trials using alternate hands. We compared mean FTT score and the coefficient of variation between diagnostic groups. FTT scores in IPD were inversely correlated with Hoehn and Yahr stage (p < 0.001) and the United Parkinson Disease Rating Scale III (motor) subscale (p < 0.001). FTT scores were significantly lower in PMD (mean = 41.72) when compared to the other diagnostic groups after controlling for age. The coefficient of variation was not significantly different between diagnostic groups. ROC analysis identified a cutoff FTT ratio of 0.670 or less was 89.1% specific and 76.9% sensitive for the diagnosis of PMD. We conclude the FTT can provide supportive evidence for the diagnosis of PMD.

[1]  S. Bressman,et al.  The diagnosis of dystonia , 2006, The Lancet Neurology.

[2]  M. Hoehn Parkinson's disease: progression and mortality. , 1987, Advances in neurology.

[3]  S. Factor,et al.  Psychogenic movement disorders: frequency, clinical profile, and characteristics. , 1995, Journal of neurology, neurosurgery, and psychiatry.

[4]  M. Schlossberg The Halstead-Reitan Neuropsychological Test Battery: Theory and Clinical Interpretation. , 1986 .

[5]  S. Fahn Unified Parkinson's Disease Rating Scale , 1987 .

[6]  C. Marsden,et al.  Recent Developments in Parkinson's Disease , 1986 .

[7]  Hoehn Mm,et al.  Parkinson's disease: progression and mortality. , 1987 .

[8]  Francis I. Kittredge,et al.  Assessment: Intensive EEG/video monitoring for epilepsy , 1989 .

[9]  J. Rothwell,et al.  Parkinsonism following bilateral lesions of the globus pallidus: performance on a variety of motor tasks shows similarities with Parkinson’s disease , 2005, Journal of Neurology, Neurosurgery & Psychiatry.

[10]  M. Brin,et al.  Consensus Statement of the Movement Disorder Society on Tremor , 2008, Movement disorders : official journal of the Movement Disorder Society.

[11]  Brain and intelligence: A quantitative study of the frontal lobes. , 1949 .

[12]  J. Rabe-Jabłońska,et al.  [Affective disorders in the fourth edition of the classification of mental disorders prepared by the American Psychiatric Association -- diagnostic and statistical manual of mental disorders]. , 1993, Psychiatria polska.

[13]  R. Heaton,et al.  Prospects for faking believable deficits on neuropsychological testing. , 1978, Journal of consulting and clinical psychology.

[14]  L. Matheson,et al.  Use of maximum voluntary effort grip strength testing to identify symptom magnification syndrome in persons with low back pain , 1998 .

[15]  Gábor Fazekas,et al.  Analysis of finger-tapping movement , 2005, Journal of Neuroscience Methods.

[16]  G. Demakis Serial malingering on verbal and nonverbal fluency and memory measures: an analog investigation. , 1999, Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists.

[17]  L. Rapport,et al.  Effects of coaching on malingered motor function profiles. , 1998, Journal of clinical and experimental neuropsychology.

[18]  Sue Leurgans,et al.  Rating scale for psychogenic movement disorders: Scale development and clinimetric testing , 2005, Movement disorders : official journal of the Movement Disorder Society.

[19]  A. Samii,et al.  Alternating two finger tapping with contralateral activation is an objective measure of clinical severity in Parkinson's disease and correlates with PET , 2001, Parkinsonism & related disorders.

[20]  S. Fahn Members of the UPDRS Development Committee. Unified Parkinson's Disease Rating Scale , 1987 .

[21]  K. Boone,et al.  SENSITIVITY AND SPECIFICITY OF FINGER TAPPING TEST SCORES FOR THE DETECTION OF SUSPECT EFFORT , 2005, The Clinical neuropsychologist.

[22]  M. Vokaer,et al.  Effects of levodopa on upper limb mobility and gait in Parkinson’s disease , 2003, Journal of neurology, neurosurgery, and psychiatry.

[23]  M. Hallett,et al.  Diagnosing psychogenic movement disorders—which criteria should be used in clinical practice? , 2007, Nature Clinical Practice Neurology.

[24]  M. Hallett Psychogenic parkinsonism , 2011, Journal of the Neurological Sciences.

[25]  J. G. Nutt,et al.  Long-duration response to levodopa , 1995, Neurology.

[26]  T. Hastie,et al.  Quantitative measurements of alternating finger tapping in Parkinson's disease correlate with UPDRS motor disability and reveal the improvement in fine motor control from medication and deep brain stimulation , 2005, Movement disorders : official journal of the Movement Disorder Society.

[27]  W. Weiner,et al.  Psychogenic tremors , 1989, Neurology.

[28]  J. Hughes,et al.  Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. , 1992, Journal of neurology, neurosurgery, and psychiatry.

[29]  Gavin Giovannoni,et al.  The bradykinesia akinesia incoordination test (BRAIN TEST©), an objective and user‐friendly means to evaluate patients with Parkinsonism , 2000, Movement disorders : official journal of the Movement Disorder Society.

[30]  Dc Washington Diagnostic and Statistical Manual of Mental Disorders, 4th Ed. , 1994 .

[31]  J. Sackellares,et al.  Intellectual and neuropsychological features of patients with psychogenic pseudoseizures , 1999, Psychiatry Research.