Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development
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P. Van Vlierberghe | K. Liang | F. van Nieuwerburgh | A. Kuchmiy | M. Lavaert | J. Roels | B. Vandekerckhove | G. Leclercq | T. Taghon | Steven Strubbe | Matthias De Decker
[1] D. Wiest,et al. Faculty Opinions recommendation of γδ T cells: pleiotropic immune effectors with therapeutic potential in cancer. , 2020 .
[2] D. Wiest,et al. Faculty Opinions recommendation of γδ TCR ligands: the quest to solve a 500-million-year-old mystery. , 2020 .
[3] Timothy L. Tickle,et al. Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes. , 2020, Immunity.
[4] S. Teichmann,et al. A cell atlas of human thymic development defines T cell repertoire formation , 2020, Science.
[5] M. Weirauch,et al. AP-1 activity induced by co-stimulation is required for chromatin opening during T cell activation , 2019, The Journal of experimental medicine.
[6] Brigitta Stockinger,et al. Meningeal γδ T cell–derived IL-17 controls synaptic plasticity and short-term memory , 2019, Science Immunology.
[7] A. Tutt,et al. An innate-like Vδ1+ γδ T cell compartment in the human breast is associated with remission in triple-negative breast cancer , 2019, Science Translational Medicine.
[8] Ellen V Rothenberg,et al. Single-Cell Analysis Reveals Regulatory Gene Expression Dynamics Leading to Lineage Commitment in Early T Cell Development. , 2019, Cell systems.
[9] A. Hayday. γδ T Cell Update: Adaptate Orchestrators of Immune Surveillance , 2019, The Journal of Immunology.
[10] S. Coffelt,et al. γδ T cells: pleiotropic immune effectors with therapeutic potential in cancer , 2019, Nature Reviews Cancer.
[11] B. Willcox,et al. γδ TCR ligands: the quest to solve a 500-million-year-old mystery , 2019, Nature Immunology.
[12] Paul A Bates,et al. The γδTCR combines innate immunity with adaptive immunity by utilizing spatially distinct regions for agonist selection and antigen responsiveness , 2018, Nature Immunology.
[13] Jun Sese,et al. ChIP‐Atlas: a data‐mining suite powered by full integration of public ChIP‐seq data , 2018, EMBO reports.
[14] Lisa K. Peterson,et al. TCR signal strength controls thymic differentiation of iNKT cell subsets , 2018, Nature Communications.
[15] K. Nakayama,et al. Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding , 2018, Immunity.
[16] I. Taniuchi. CD4 Helper and CD8 Cytotoxic T Cell Differentiation. , 2018, Annual review of immunology.
[17] R. Geffers,et al. Publisher Correction: Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection , 2018, Nature Immunology.
[18] Nicholas A. Sinnott-Armstrong,et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues , 2017, Nature Methods.
[19] R. Geffers,et al. Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection , 2017, Nature Immunology.
[20] L. Steinmetz,et al. Human haematopoietic stem cell lineage commitment is a continuous process , 2017, Nature Cell Biology.
[21] D. Casero,et al. The T-ALL related gene BCL11B regulates the initial stages of human T-cell differentiation , 2017, Leukemia.
[22] F. Staal,et al. Loss of CD44dim Expression from Early Progenitor Cells Marks T-Cell Lineage Commitment in the Human Thymus , 2017, Front. Immunol..
[23] Andrew D. Rouillard,et al. Enrichr: a comprehensive gene set enrichment analysis web server 2016 update , 2016, Nucleic Acids Res..
[24] F. Speleman,et al. GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate , 2016, Nature Communications.
[25] E. Rothenberg,et al. Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control. , 2016, Advances in immunology.
[26] D. Casero,et al. LncRNA profiling of human lymphoid progenitors reveals transcriptional divergence of B and T lineages , 2015, Nature Immunology.
[27] Nathan C. Sheffield,et al. ChIPmentation: fast, robust, low-input ChIP-seq for histones and transcription factors , 2015, Nature Methods.
[28] Howard Y. Chang,et al. ATAC‐seq: A Method for Assaying Chromatin Accessibility Genome‐Wide , 2015, Current protocols in molecular biology.
[29] W. Huber,et al. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.
[30] Ellen V. Rothenberg,et al. Developmental gene networks: a triathlon on the course to T cell identity , 2014, Nature Reviews Immunology.
[31] Fidel Ramírez,et al. deepTools: a flexible platform for exploring deep-sequencing data , 2014, Nucleic Acids Res..
[32] D. Wiest,et al. The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification , 2014, The Journal of experimental medicine.
[33] Keji Zhao,et al. Expression and regulation of lincRNAs during T cell development and differentiation , 2013, Nature Immunology.
[34] Avi Ma'ayan,et al. Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool , 2013, BMC Bioinformatics.
[35] G. Nolan,et al. The transcriptional landscape of αβ T cell differentiation , 2013, Nature Immunology.
[36] Lihua Julie Zhu,et al. Integrative analysis of ChIP-chip and ChIP-seq dataset. , 2013, Methods in molecular biology.
[37] Thomas R. Gingeras,et al. STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..
[38] Iannis Aifantis,et al. ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression. , 2012, Cancer cell.
[39] M. Ciofani,et al. Determining γδ versus αβ T cell development , 2010, Nature Reviews Immunology.
[40] D. Wiest,et al. Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice. , 2010, Seminars in immunology.
[41] C. Glass,et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. , 2010, Molecular cell.
[42] D. Wiest,et al. Towards a molecular understanding of the differential signals regulating αβ / γδ T lineage choice , 2010 .
[43] David S. Lapointe,et al. ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data , 2010, BMC Bioinformatics.
[44] M. Ciofani,et al. Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent. , 2009, Immunity.
[45] B. Vandekerckhove,et al. An early decrease in Notch activation is required for human TCR-alphabeta lineage differentiation at the expense of TCR-gammadelta T cells. , 2009, Blood.
[46] E. Rothenberg,et al. Molecular mechanisms that control mouse and human TCR-αβ and TCR-γδ T cell development , 2008, Seminars in Immunopathology.
[47] Xiuli Wang,et al. Human intrathymic lineage commitment is marked by differential CD7 expression: identification of CD7- lympho-myeloid thymic progenitors. , 2008, Blood.
[48] A. Bhandoola,et al. Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from. , 2007, Immunity.
[49] T. Boehm,et al. Thymus-homing precursors and the thymic microenvironment. , 2006, Trends in immunology.
[50] J. V. van Dongen,et al. Human thymus contains multipotent progenitors with T/B lymphoid, myeloid, and erythroid lineage potential. , 2006, Blood.
[51] L. Thompson,et al. Human αβ and γδ Thymocyte Development: TCR Gene Rearrangements, Intracellular TCRβ Expression, and γδ Developmental Potential—Differences between Men and Mice12 , 2006, The Journal of Immunology.
[52] E. Rothenberg,et al. Developmental and Molecular Characterization of Emerging β- and γδ-Selected Pre-T Cells in the Adult Mouse Thymus , 2006 .
[53] Dick de Ridder,et al. New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling , 2005, The Journal of experimental medicine.
[54] P. Love,et al. TCR Signal Strength Influences αβ/γδ Lineage Fate , 2005 .
[55] M. Carleton,et al. Attenuation of γδTCR Signaling Efficiently Diverts Thymocytes to the αβ Lineage , 2005 .
[56] B. Verhasselt,et al. HOX-A10 regulates hematopoietic lineage commitment: evidence for a monocyte-specific transcription factor. , 2002, Blood.
[57] J. V. van Dongen,et al. Disruption of αβ but not of γδ T cell development by overexpression of the helix–loop–helix protein Id3 in committed T cell progenitors , 1999 .