Notch4 reveals a novel mechanism regulating Notch signal transduction.
暂无分享,去创建一个
S. Dunwoodie | G. Chapman | J. Major | S. Pursglove | J. Szot | A. C. James | K. Iyer | Justin O Szot | A. James
[1] D. Anastassiou,et al. Notch and VEGF pathways play distinct but complementary roles in tumor angiogenesis , 2013, Vascular cell.
[2] B. Styp-Rekowska,et al. Inhibition of Notch signaling induces extensive intussusceptive neo-angiogenesis by recruitment of mononuclear cells , 2013, Angiogenesis.
[3] R. Adams,et al. Notch controls retinal blood vessel maturation and quiescence , 2013, Development.
[4] M. Hellström,et al. Notch as a hub for signaling in angiogenesis. , 2013, Experimental cell research.
[5] D. Accili,et al. Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability , 2013, Nature Medicine.
[6] Rong A. Wang,et al. Notch4 is required for tumor onset and perfusion , 2013, Vascular cell.
[7] F. le Noble,et al. Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models , 2013, Development.
[8] M. Oshimura,et al. Transplantation of Genetically Corrected Human iPSC-Derived Progenitors in Mice with Limb-Girdle Muscular Dystrophy , 2012, Science Translational Medicine.
[9] A. Karsan,et al. Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling , 2012, Proceedings of the National Academy of Sciences.
[10] F. le Noble,et al. Extrinsic Notch Ligand Delta-Like 1 Regulates Tip Cell Selection and Vascular Branching Morphogenesis , 2012, Circulation research.
[11] Tyson N. Kim,et al. Notch4 Normalization Reduces Blood Vessel Size in Arteriovenous Malformations , 2012, Science Translational Medicine.
[12] J. Aster,et al. Notch Ankyrin Repeat Domain Variation Influences Leukemogenesis and Myc Transactivation , 2011, PloS one.
[13] S. Dunwoodie,et al. A cell autonomous role for the Notch ligand Delta‐like 3 in αβ T‐cell development , 2011, Immunology and cell biology.
[14] Shayn M. Peirce,et al. Rapid Analysis of Vessel Elements (RAVE): A Tool for Studying Physiologic, Pathologic and Tumor Angiogenesis , 2011, PloS one.
[15] E. Kremmer,et al. Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis. , 2011, Human molecular genetics.
[16] Hervé Rouault,et al. Mechanism and Significance of cis-Inhibition in Notch Signalling , 2011, Current Biology.
[17] J. Waltenberger,et al. Feed-forward Signaling by Membrane-bound Ligand Receptor Circuit , 2010, The Journal of Biological Chemistry.
[18] K. Ross,et al. Characterization of Notch1 Antibodies That Inhibit Signaling of Both Normal and Mutated Notch1 Receptors , 2010, PloS one.
[19] Rong A. Wang,et al. Constitutively active endothelial Notch4 causes lung arteriovenous shunts in mice. , 2010, American journal of physiology. Lung cellular and molecular physiology.
[20] P. V. van Diest,et al. Metalloprotease ADAM10 Is Required for Notch1 Site 2 Cleavage* , 2009, The Journal of Biological Chemistry.
[21] G. Weinmaster,et al. Selective Use of ADAM10 and ADAM17 in Activation of Notch1 Signaling , 2009, Molecular and Cellular Biology.
[22] J. Aster,et al. Effects of S1 Cleavage on the Structure, Surface Export, and Signaling Activity of Human Notch1 and Notch2 , 2009, PloS one.
[23] G. Weinmaster,et al. Numb Regulates Post-endocytic Trafficking and Degradation of Notch1* , 2009, The Journal of Biological Chemistry.
[24] R. Adams,et al. DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries. , 2009, Blood.
[25] G. Ulrich Nienhaus,et al. mRuby, a Bright Monomeric Red Fluorescent Protein for Labeling of Subcellular Structures , 2009, PloS one.
[26] Holger Gerhardt,et al. Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis. , 2009, Developmental cell.
[27] Rong A. Wang,et al. Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis , 2008, Development.
[28] Tyson N. Kim,et al. Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice , 2008, Proceedings of the National Academy of Sciences.
[29] G. Goodall,et al. Attenuation of leakiness in doxycycline-inducible expression via incorporation of 3' AU-rich mRNA destabilizing elements. , 2008, BioTechniques.
[30] A. Israël,et al. AIP4/Itch Regulates Notch Receptor Degradation in the Absence of Ligand , 2008, PloS one.
[31] Jianzhong Huang,et al. A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis. , 2008, Cancer research.
[32] M. Skobe,et al. Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. , 2007, The Journal of clinical investigation.
[33] J. Aster,et al. Structural basis for autoinhibition of Notch , 2007, Nature Structural &Molecular Biology.
[34] J. Folkman. Opinion: Angiogenesis: an organizing principle for drug discovery? , 2007, Nature Reviews Drug Discovery.
[35] G. Thurston,et al. Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting , 2007, Proceedings of the National Academy of Sciences.
[36] Antonio Duarte,et al. The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching , 2007, Proceedings of the National Academy of Sciences.
[37] Marcus Fruttiger,et al. Development of the retinal vasculature , 2007, Angiogenesis.
[38] H. Drexler,et al. Notch Ligand Delta-Like 1 Is Essential for Postnatal Arteriogenesis , 2007, Circulation research.
[39] Holger Gerhardt,et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis , 2007, Nature.
[40] K. Tsubota,et al. Functional Analysis of an Established Mouse Vascular Endothelial Cell Line , 2007, Journal of Vascular Research.
[41] G. Du,et al. 3′ End cDNA amplification using classic RACE , 2006, Nature Protocols.
[42] U. Lendahl,et al. High levels of Notch signaling down-regulate Numb and Numblike , 2006, The Journal of cell biology.
[43] Martin Friedlander,et al. Mechanisms of endothelial cell guidance and vascular patterning in the developing mouse retina , 2006, Progress in Retinal and Eye Research.
[44] G. Stormo,et al. Target Selectivity of Vertebrate Notch Proteins , 2006, Journal of Biological Chemistry.
[45] Peter Carmeliet,et al. Angiogenesis in life, disease and medicine , 2005, Nature.
[46] Z. Werb,et al. Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[47] K. Sakamoto,et al. Distinct roles of EGF repeats for the Notch signaling system. , 2005, Experimental cell research.
[48] M. Vooijs,et al. Ectodomain Shedding and Intramembrane Cleavage of Mammalian Notch Proteins Are Not Regulated through Oligomerization* , 2004, Journal of Biological Chemistry.
[49] Gavin Thurston,et al. Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[50] Marcus Fruttiger,et al. Periodic Delta-like 4 expression in developing retinal arteries. , 2004, Gene expression patterns : GEP.
[51] Janet Rossant,et al. Dosage-sensitive requirement for mouse Dll4 in artery development. , 2004, Genes & development.
[52] L. Maquat. Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics , 2004, Nature Reviews Molecular Cell Biology.
[53] J. Kitajewski,et al. Notch Signaling in Primary Endothelial Cells , 2003, Annals of the New York Academy of Sciences.
[54] D. Ish-Horowicz,et al. Periodic Lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to notch signaling. , 2002, Developmental cell.
[55] U. Lendahl,et al. A Sensitive and Quantitative Assay for Measuring Cleavage of Presenilin Substrates* , 2002, The Journal of Biological Chemistry.
[56] O. Ohara,et al. Intracellular cell-autonomous association of Notch and its ligands: a novel mechanism of Notch signal modification. , 2002, Developmental biology.
[57] Raphael Kopan,et al. Murine Notch Homologs (N1–4) Undergo Presenilin-dependent Proteolysis* , 2001, The Journal of Biological Chemistry.
[58] G. Weinmaster,et al. Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels , 2001, Mechanisms of Development.
[59] C. Niehrs,et al. Nrarp is a novel intracellular component of the Notch signaling pathway. , 2001, Genes & development.
[60] J. Rossant,et al. Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[61] K. Mackey,et al. Analysis of RNA by Northern and Slot‐Blot Hybridization , 2001, Current protocols in neuroscience.
[62] G. Weinmaster,et al. Ligand-induced signaling in the absence of furin processing of Notch1. , 2001, Developmental biology.
[63] G. Weinmaster,et al. Notch4 and Jagged-1 induce microvessel differentiation of rat brain endothelial cells. , 2000, Microvascular research.
[64] M. Gessler,et al. Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes. , 2000, Biochemical and biophysical research communications.
[65] J. Sundberg,et al. Notch signaling is essential for vascular morphogenesis in mice. , 2000, Genes & development.
[66] J. Sklar,et al. Calcium Depletion Dissociates and Activates Heterodimeric Notch Receptors , 2000, Molecular and Cellular Biology.
[67] Raphael Kopan,et al. A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1. , 2000, Molecular cell.
[68] G. Weinmaster,et al. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. , 1999, Human molecular genetics.
[69] William J. Ray,et al. A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain , 1999, Nature.
[70] A. Israël,et al. The Notch1 receptor is cleaved constitutively by a furin-like convertase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[71] B. Trask,et al. Cloning, characterization, and the complete 56.8-kilobase DNA sequence of the human NOTCH4 gene. , 1998, Genomics.
[72] Raphael Kopan,et al. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain , 1998, Nature.
[73] S. Minoguchi,et al. Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives. , 1997, Development.
[74] R. Beddington,et al. Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo. , 1997, Development.
[75] S. Artavanis-Tsakonas,et al. Intracellular Cleavage of Notch Leads to a Heterodimeric Receptor on the Plasma Membrane , 1997, Cell.
[76] T. Ikemura,et al. Proto‐oncogene of int‐3, a mouse Notch homologue, is expressed in endothelial cells during early embryogenesis , 1997, Genes to cells : devoted to molecular & cellular mechanisms.
[77] S. Minoguchi,et al. Functional conservation of mouse Notch receptor family members , 1996, FEBS letters.
[78] D. Sassoon,et al. Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. , 1996, Development.
[79] Christel Brou,et al. Signalling downstream of activated mammalian Notch , 1995, Nature.
[80] H. Weintraub,et al. The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD. , 1994, Development.
[81] G. Weinmaster,et al. Notch1 is essential for postimplantation development in mice. , 1994, Genes & development.
[82] J. Rossant,et al. Expression analysis of a Notch homologue in the mouse embryo. , 1992, Developmental biology.
[83] L. Drewes,et al. A lock-docking oligo(dT) primer for 5' and 3' RACE PCR. , 1992, PCR methods and applications.
[84] R. Greenspan,et al. Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. , 1992, Development.
[85] K. Umesono,et al. Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors , 1991, Cell.
[86] D. Sillence,et al. Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype. , 2006, American journal of human genetics.
[87] Masaaki Ii,et al. Serveur Académique Lausannois SERVAL serval.unil.ch , 2022 .