OBJECTIVES
The aim of this randomized clinical trial was to evaluate the desensitizing and remineralizing effect of a new zinc-hydroxyapatite-based paste in sites affected by Molar-Incisor Hypomineralization (MIH), by assessing dental sensitivity, tooth wear and periodontal indexes.
MATERIALS AND METHODS
25 patients with presence of 1 enamel demineralization of permanent molars and incisors in two different quadrants were recruited. After professional dental hygiene, a domiciliary hydroxyapatite-based paste was assigned and recommended to be applied on 2 MIH teeth in one random quadrant (Test group), while the 2 contralateral MIH teeth did not undergo paste application (Control group). The following primary outcomes were assessed: Plaque Control Record (PCR), Bleeding Index (BI), MIH Treatment Need Index (MIH-TNI) and Schiff Air Index (SAI).
RESULTS
No significant inter- and intragroup differences were found for PI and BI, except for both intragroup T0-T1. For MIH-TNI, significant intergroup differences were detectable in the Test group after 9 months of treatment. For SAI values, no significant differences were found in the Control group, while in the Test group significant lower values were found after 1 and 3 months since baseline, respectively.
CONCLUSIONS AND CLINICAL RELEVANCE
Biomimetic zinc-hydroxyapatite showed a desensitizing effect when used to treat MIH.