Indoor environment and respiratory symptoms in children living in the Dutch-German borderland.

OBJECTIVE To investigate the relation between indoor environmental risk factors and respiratory symptoms in 7-8-year-old children living in the Dutch-German borderland. METHODS A nested case-control study was conducted among children participating in a large longitudinal study on respiratory health. Parents of all 781 children with respiratory complaints and an equal number of randomly selected controls were asked to complete a questionnaire, including questions on indoor environment. RESULTS The parents of 1191 children (76.2%) participated. Past exposure to environmental (OR = 2.73, 95% CI 1.14-6.67) as well as in utero exposure (OR = 2.28, 95% CI 1.15-4.53) to tobacco smoke, use of an unvented geyser for water heating (OR = 3.01, 95% CI 1.21-7.56), long-term exposure to dampness (OR = 2.98, 95% CI 1.10-8.28) or pets (OR = 2.18, 95% CI 1.39-3.42) increased the risk of asthmatic symptoms in 7-8-year-old children. A middle or low socio-economic status also increased the risk of asthmatic symptoms. An inverse association with asthmatic symptoms was seen for wall-to-wall carpeting (OR = 0.57, 95% CI 0.33-0.95) and insulation measures (OR = 0.46, 95% CI 0.25-0.83). Except for the presence of an unvented geyser, these environmental risk factors also presented a risk for coughing symptoms in children. CONCLUSION This study showed an increased risk of respiratory symptoms in children exposed to several indoor environmental risk factors.

[1]  D K Wagener,et al.  Breathing better or wheezing worse? The changing epidemiology of asthma morbidity and mortality. , 1993, Annual review of public health.

[2]  D. Strachan Damp housing and childhood asthma: validation of reporting of symptoms. , 1988, BMJ.

[3]  Richard Beasley,et al.  Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC , 1998, The Lancet.

[4]  A. Kosheleva,et al.  Housing characteristics and children's respiratory health in the Russian Federation. , 2004, American journal of public health.

[5]  I. Tager Health effects of "passive smoking" in children. , 1989, Chest.

[6]  D. Jarvis,et al.  Individual use of antiasthmatic drugs in the European Community Respiratory Health Survey. , 1998, The European respiratory journal.

[7]  M. Eisner,et al.  Gas stove use and respiratory health among adults with asthma in NHANES III , 2003, Occupational and environmental medicine.

[8]  E. Peterson,et al.  Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age. , 2002, JAMA.

[9]  P. Corey,et al.  The effect of domestic factors on respiratory symptoms and FEV1. , 1989, International journal of epidemiology.

[10]  M. Klinnert,et al.  Relation between house-dust endotoxin exposure, type 1 T-cell development, and allergen sensitisation in infants at high risk of asthma , 2000, The Lancet.

[11]  A. Woodcock,et al.  ABC of allergies: Avoiding exposure to indoor allergens , 1998, BMJ.

[12]  P. Gergen Social class and asthma--distinguishing between the disease and the diagnosis. , 1996, American journal of public health.

[13]  J S Boleij,et al.  Respiratory health effects of the indoor environment in a population of Dutch children. , 1990, The American review of respiratory disease.

[14]  M. Bracken,et al.  Exposure to NO2 and Nitrous Acid and Respiratory Symptoms in the First Year of Life , 2004, Epidemiology.

[15]  D. Strachan,et al.  International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. , 1995, The European respiratory journal.

[16]  Sidria Asthma and respiratory symptoms in 6-7 yr old Italian children: gender, latitude, urbanization and socioeconomic factors , 1997 .

[17]  D. Strachan,et al.  Respiratory symptoms and home environment in children: a national survey , 1999, Thorax.

[18]  P. Sly,et al.  Effects of maternal smoking during pregnancy and a family history of asthma on respiratory function in newborn infants , 1996, The Lancet.

[19]  J M Peters,et al.  Effects of maternal smoking during pregnancy and environmental tobacco smoke on asthma and wheezing in children. , 2001, American journal of respiratory and critical care medicine.

[20]  Edward B Rappaport,et al.  environmental tobacco smoke exposure and childhood lung function , 2022 .

[21]  Olf Herbarth,et al.  Redecoration of apartments promotes obstructive bronchitis in atopy risk infants – Results of the LARS study , 2003, International Journal of Hygiene and Environmental Health.

[22]  S. A. Perlin,et al.  Influences of asthma and household environment on lung function in children and adolescents: the third national health and nutrition examination survey. , 2003, American journal of epidemiology.

[23]  M Svartengren,et al.  Indoor exposures and recurrent wheezing in infants: a study in the BAMSE cohort , 2004, Acta paediatrica.

[24]  M. Abramson,et al.  Respiratory symptoms in children and indoor exposure to nitrogen dioxide and gas stoves. , 1998, American journal of respiratory and critical care medicine.

[25]  A. Woodcock,et al.  Tobacco smoke exposure, wheeze, and atopy , 2004, Pediatric pulmonology.

[26]  R. Burnett,et al.  Respiratory health effects of home dampness and molds among Canadian children. , 1991, American journal of epidemiology.

[27]  A P Verhoeff,et al.  Damp housing and childhood respiratory symptoms: the role of sensitization to dust mites and molds. , 1995, American journal of epidemiology.

[28]  D. Strachan,et al.  Health effects of passive smoking. 3. Parental smoking and prevalence of respiratory symptoms and asthma in school age children. , 1997, Thorax.

[29]  A. Mielck,et al.  Severity of childhood asthma by socioeconomic status. , 1996, International journal of epidemiology.

[30]  G Wesseling,et al.  Adverse effects of the indoor environment on respiratory health in primary school children. , 1995, Environmental research.

[31]  D. Strachan Family size, infection and atopy: the first decade of the 'hygiene hypothesis' , 2000, Thorax.

[32]  G. Swaen,et al.  Differences in asthma diagnosis and medication use in children living in Germany and the Netherlands. , 2005, Primary care respiratory journal : journal of the General Practice Airways Group.

[33]  G. Russell,et al.  Continuing increase in respiratory symptoms and atopy in Aberdeen schoolchildren , 1996, BMJ.

[34]  Deborah Jarvis,et al.  Variations in the prevalence of respiratory symptoms, self-reported asthma attacks, and use of asthma medication in the European Community Respiratory Health Survey (ECRHS). , 1996, The European respiratory journal.

[35]  W. Morgan,et al.  Recurrent cough in childhood and its relation to asthma. , 1996, American journal of respiratory and critical care medicine.

[36]  D. Hui,et al.  Factors associated with difference in prevalence of asthma in children from three cities in China: multicentre epidemiological survey , 2004, BMJ : British Medical Journal.

[37]  N. Pearce,et al.  Diet and asthma, allergic rhinoconjunctivitis and atopic eczema symptom prevalence: an ecological analysis of the International Study of Asthma and Allergies in Childhood (ISAAC) data. ISAAC Phase One Study Group. , 2001, The European respiratory journal.

[38]  J. Stoddard,et al.  Impact of parental smoking on the prevalence of wheezing respiratory illness in children. , 1995, American journal of epidemiology.

[39]  E. Barletta Asthma and respiratory symptoms in 6-7 yr old Italian children: gender, latitude, urbanization and socioeconomic factors. SIDRIA (Italian Studies on Respiratory Disorders in Childhood and the Environment). , 1997, The European respiratory journal.

[40]  M. Kerkhof,et al.  The effect of gas cooking on bronchial hyperresponsiveness and the role of immunoglobulin E. , 1999, The European respiratory journal.

[41]  T. Platts-Mills,et al.  Asthma, type-1 allergy and related conditions in 7- and 8-year-old children in northern Sweden: prevalence rates and risk factor pattern. , 1998, Respiratory medicine.

[42]  G. Pershagen,et al.  PARENTAL SMOKING, URINARY COTININE, AND WHEEZING BRONCHITIS IN CHILDREN , 1995, Epidemiology.

[43]  D. Strachan,et al.  A national survey of asthma prevalence, severity, and treatment in Great Britain. , 1994, Archives of disease in childhood.