C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors
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Philipp S. Hoppe | F. Lauridsen | B. Porse | J. Waage | N. Rapin | F. O. Bagger | J. S. Jakobsen | T. Schroeder | Anne-Katrine Frank | M. Hasemann | M. B. Schuster
[1] J. Milbrandt,et al. DNA-binding specificity of NGFI-A and related zinc finger transcription factors , 1995, Molecular and cellular biology.
[2] D. Tenen,et al. PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells. , 1996, Blood.
[3] B. Porse,et al. E2F Repression by C/EBPα Is Required for Adipogenesis and Granulopoiesis In Vivo , 2001, Cell.
[4] D. Tenen,et al. Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: possible role in lineage commitment decisions. , 2002, Blood.
[5] Irving L. Weissman,et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells , 2003, Nature.
[6] Pu Zhang,et al. Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha. , 2004, Immunity.
[7] S. Orkin,et al. Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells , 2004, Nature.
[8] T. Graf,et al. Stepwise Reprogramming of B Cells into Macrophages , 2004, Cell.
[9] S Miyano,et al. Open source clustering software. , 2004, Bioinformatics.
[10] A. Iwama,et al. Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. , 2004, Immunity.
[11] S. Orkin,et al. Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival. , 2004, Genes & development.
[12] K. Akashi,et al. Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation. , 2005, Blood.
[13] Marie S. Hasemann,et al. Loss of C/EBPα cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage , 2005, The Journal of experimental medicine.
[14] Peter F. Johnson,et al. Molecular stop signs: regulation of cell-cycle arrest by C/EBP transcription factors , 2005, Journal of Cell Science.
[15] James A. Cuff,et al. A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells , 2006, Cell.
[16] Xi C. He,et al. PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention , 2006, Nature.
[17] S. Morrison,et al. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells , 2006, Nature.
[18] Ryan Brinkman,et al. Long-term propagation of distinct hematopoietic differentiation programs in vivo. , 2007, Cell stem cell.
[19] S. Morrison,et al. Sox17 Dependence Distinguishes the Transcriptional Regulation of Fetal from Adult Hematopoietic Stem Cells , 2007, Cell.
[20] G. Ligresti,et al. Regulation of the Extrinsic Apoptotic Pathway by the Extracellular Matrix Glycoprotein EMILIN2 , 2007, Molecular and Cellular Biology.
[21] J. Fisher,et al. Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors. , 2007, Cell stem cell.
[22] C. Nerlov. The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation control. , 2007, Trends in cell biology.
[23] Leonard I. Zon,et al. Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal , 2008, Nature.
[24] Elizabeth A. Kruse,et al. The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells , 2008, Nature Immunology.
[25] Clifford A. Meyer,et al. Model-based Analysis of ChIP-Seq (MACS) , 2008, Genome Biology.
[26] M. van Lohuizen,et al. Stem cell regulation by polycomb repressors: postponing commitment. , 2008, Current opinion in cell biology.
[27] Lina A. Thoren,et al. NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements. , 2008, Genes & development.
[28] Cole Trapnell,et al. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.
[29] Lucy Skrabanek,et al. Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features. , 2009, Blood.
[30] R. Jaenisch,et al. DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction , 2009, Nature Genetics.
[31] R. Månsson,et al. Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML. , 2009, Cancer cell.
[32] E. Reddy,et al. Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation , 2009, Proceedings of the National Academy of Sciences.
[33] Philipp S. Hoppe,et al. The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis. , 2009, Blood.
[34] G. Crabtree,et al. The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells , 2009, Nature Immunology.
[35] T. Suda,et al. Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon–dependent exhaustion , 2009, Nature Medicine.
[36] T. Enver,et al. Forcing cells to change lineages , 2009, Nature.
[37] Andreas Trumpp,et al. IFNα activates dormant haematopoietic stem cells in vivo , 2009, Nature.
[38] Philipp S. Hoppe,et al. Hematopoietic Cytokines Can Instruct Lineage Choice , 2009, Science.
[39] S. Orkin,et al. DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. , 2009, Cell stem cell.
[40] Cory Y. McLean,et al. GREAT improves functional interpretation of cis-regulatory regions , 2010, Nature Biotechnology.
[41] Nathan C Boles,et al. Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. , 2010, Cell stem cell.
[42] Alistair L. J. Symonds,et al. Early Growth Response Gene-2 (Egr-2) Regulates the Development of B and T Cells , 2011, PloS one.
[43] P. Vyas,et al. Generation of bivalent chromatin domains during cell fate decisions , 2011, Epigenetics & Chromatin.
[44] P. Opolon,et al. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. , 2011, Cancer cell.
[45] G. Smyth,et al. Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice. , 2011, Blood.
[46] O. Abdel-Wahab,et al. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. , 2011, Cancer cell.
[47] Juri Rappsilber,et al. TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity , 2011, Nature.
[48] Riitta Lahesmaa,et al. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. , 2011, Cell stem cell.
[49] Andrew J. Bannister,et al. Regulation of chromatin by histone modifications , 2011, Cell Research.
[50] Kristian Helin,et al. Molecular mechanisms and potential functions of histone demethylases , 2012, Nature Reviews Molecular Cell Biology.
[51] Nathan C Boles,et al. Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice. , 2012, Cell stem cell.
[52] Harinder Singh,et al. Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling , 2012, Nature Immunology.
[53] Carsten Peterson,et al. Inferring rules of lineage commitment in haematopoiesis , 2012, Nature Cell Biology.
[54] Daniel Bilbao,et al. FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors , 2011, The EMBO journal.
[55] O. Abdel-Wahab,et al. The role of mutations in epigenetic regulators in myeloid malignancies , 2012, Nature Reviews Cancer.
[56] Felicia S. L. Ng,et al. Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells. , 2013, Molecular cell.
[57] B. Porse,et al. Lack of the p42 form of C/EBPα leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors. , 2013, Experimental hematology.
[58] D. Tenen,et al. C/EBPa controls acquisition and maintenance of adult hematopoietic stem cell quiescence , 2013, Nature Cell Biology.
[59] Ole Winther,et al. HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis , 2012, Nucleic Acids Res..