Ultrafast detection and quantification of brain signaling molecules with carbon fiber microelectrodes.

Carbon fiber microelectrodes provide the ideal platform for performing ultrafast, selective measurements of electroactive brain molecules. This article highlights the current status of the use of carbon fiber microelectrodes in neurochemical measurements, outlining the most cutting edge findings and technological advances in amperometry and fast-scan cyclic voltammetry.

[1]  Pedram Mohseni,et al.  Development of the Wireless Instantaneous Neurotransmitter Concentration System for intraoperative neurochemical monitoring using fast-scan cyclic voltammetry. , 2009, Journal of neurosurgery.

[2]  R. Blakely,et al.  Transgenic elimination of high-affinity antidepressant and cocaine sensitivity in the presynaptic serotonin transporter , 2011, Proceedings of the National Academy of Sciences.

[3]  R. Wightman,et al.  Voltammetric detection of 5-hydroxytryptamine release in the rat brain. , 2009, Analytical chemistry.

[4]  L. Daws.  Unfaithful neurotransmitter transporters: focus on serotonin uptake and implications for antidepressant efficacy. , 2009, Pharmacology & therapeutics.

[5]  Andrew G Ewing,et al.  Hybrid capillary-microfluidic device for the separation, lysis, and electrochemical detection of vesicles. , 2009, Analytical chemistry.

[6]  Rachel A. Millstein,et al.  Ethanol Inhibits Clearance of Brain Serotonin by a Serotonin Transporter-independent Mechanism , 2022 .

[7]  W. A. Owens,et al.  In vivo analysis of serotonin clearance in rat hippocampus reveals that repeated administration of p‐methoxyamphetamine (PMA), but not 3,4‐methylenedioxymethamphetamine (MDMA), leads to long‐lasting deficits in serotonin transporter function , 2007, Journal of neurochemistry.

[8]  R. Wightman,et al.  In vivo comparison of norepinephrine and dopamine release in rat brain by simultaneous measurements with fast‐scan cyclic voltammetry , 2011, Journal of neurochemistry.

[9]  L. Sombers,et al.  Comparison of electrode materials for the detection of rapid hydrogen peroxide fluctuations using background-subtracted fast scan cyclic voltammetry. , 2011, The Analyst.

[10]  A. Michael,et al.  An inverse correlation between the apparent rate of dopamine clearance and tonic autoinhibition in subdomains of the rat striatum: a possible role of transporter‐mediated dopamine efflux , 2011, Journal of neurochemistry.

[11]  Raag D. Airan,et al.  Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures , 2010, Nature Protocols.

[12]  Parastoo Hashemi,et al.  In vivo electrochemical evidence for simultaneous 5‐HT and histamine release in the rat substantia nigra pars reticulata following medial forebrain bundle stimulation , 2011, Journal of neurochemistry.

[13]  Sara A Love,et al.  Examining changes in cellular communication in neuroendocrine cells after noble metal nanoparticle exposure. , 2012, The Analyst.

[14]  Pavel Takmakov,et al.  Higher sensitivity dopamine measurements with faster-scan cyclic voltammetry. , 2011, Analytical chemistry.

[15]  R. Blakely,et al.  Rapid Stimulation of Presynaptic Serotonin Transport by A3 Adenosine Receptors , 2007, Journal of Pharmacology and Experimental Therapeutics.

[16]  R. Wightman,et al.  Cue-evoked dopamine release in the nucleus accumbens shell tracks reinforcer magnitude during intracranial self-stimulation , 2010, Neuroscience.

[17]  B. J. Venton,et al.  Both synthesis and reuptake are critical for replenishing the releasable serotonin pool in Drosophila , 2010, Journal of neurochemistry.

[18]  Bryce J Marquis,et al.  Investigation of noble metal nanoparticle ζ-potential effects on single-cell exocytosis function in vitro with carbon-fiber microelectrode amperometry. , 2011, The Analyst.

[19]  M. Lindau,et al.  Improved surface-patterned platinum microelectrodes for the study of exocytotic events. , 2009, Analytical chemistry.

[20]  Camelia M. Kuhnen,et al.  Delays Conferred by Escalating Costs Modulate Dopamine Release to Rewards But Not Their Predictors , 2010, The Journal of Neuroscience.

[21]  Garret D Stuber,et al.  Overoxidation of carbon-fiber microelectrodes enhances dopamine adsorption and increases sensitivity. , 2003, The Analyst.

[22]  E. Budygin,et al.  Speedball induced changes in electrically stimulated dopamine overflow in rat nucleus accumbens , 2011, Neuropharmacology.

[23]  B. J. Venton,et al.  Adenosine Release Evoked by Short Electrical Stimulations in Striatal Brain Slices is Primarily Activity Dependent. , 2010, ACS chemical neuroscience.

[24]  M. Rice,et al.  H2O2 signaling in the nigrostriatal dopamine pathway via ATP-sensitive potassium channels: issues and answers. , 2006, Antioxidants & redox signaling.

[25]  G. Gerhardt,et al.  Dopamine release from serotonergic nerve fibers is reduced in L‐DOPA‐induced dyskinesia , 2011, Journal of neurochemistry.

[26]  B. J. Venton,et al.  Fast-scan cyclic voltammetry for the detection of tyramine and octopamine , 2009, Analytical and bioanalytical chemistry.

[27]  S. Sesack,et al.  Domain‐dependent effects of DAT inhibition in the rat dorsal striatum , 2012, Journal of neurochemistry.

[28]  R. Wightman,et al.  Optimizing the Temporal Resolution of Fast-Scan Cyclic Voltammetry. , 2012, ACS chemical neuroscience.

[29]  R. Wightman,et al.  Distinguishing splanchnic nerve and chromaffin cell stimulation in mouse adrenal slices with fast-scan cyclic voltammetry. , 2011, American journal of physiology. Cell physiology.

[30]  J. McCutcheon,et al.  Sucrose‐predictive cues evoke greater phasic dopamine release than saccharin‐predictive cues , 2012, Synapse.

[31]  R. Wightman,et al.  Correlation of local changes in extracellular oxygen and pH that accompany dopaminergic terminal activity in the rat caudate–putamen , 2003, Journal of neurochemistry.

[32]  P. Shizgal,et al.  Cannabinoid Receptor Blockade Reduces the Opportunity Cost at Which Rats Maintain Operant Performance for Rewarding Brain Stimulation , 2011, The Journal of Neuroscience.

[33]  L. Sombers,et al.  Voltammetric detection of hydrogen peroxide at carbon fiber microelectrodes. , 2010, Analytical chemistry.

[34]  T. Robinson,et al.  An Animal Model of Genetic Vulnerability to Behavioral Disinhibition and Responsiveness to Reward-Related Cues: Implications for Addiction , 2010, Neuropsychopharmacology.

[35]  R. Wightman,et al.  Microelectrodes for the measurement of catecholamines in biological systems. , 1996, Analytical chemistry.

[36]  R. P. Sullivan,et al.  Optogenetic control of striatal dopamine release in rats , 2010, Journal of neurochemistry.

[37]  Parastoo Hashemi,et al.  Brain dopamine and serotonin differ in regulation and its consequences , 2012, Proceedings of the National Academy of Sciences.

[38]  Pavel Takmakov,et al.  Microfabricated FSCV-compatible microelectrode array for real-time monitoring of heterogeneous dopamine release. , 2010, The Analyst.

[39]  M. Rice,et al.  Subsecond regulation of striatal dopamine release by pre‐synaptic KATP channels , 2011, Journal of neurochemistry.

[40]  G. Gerhardt,et al.  Kinetic analysis of striatal clearance of exogenous dopamine recorded by chronoamperometry in freely-moving rats , 2002, Journal of Neuroscience Methods.

[41]  B. J. Venton,et al.  Subsecond detection of physiological adenosine concentrations using fast-scan cyclic voltammetry. , 2007, Analytical chemistry.

[42]  Pavel Takmakov,et al.  Simultaneous decoupled detection of dopamine and oxygen using pyrolyzed carbon microarrays and fast-scan cyclic voltammetry. , 2009, Analytical chemistry.

[43]  K. Deisseroth,et al.  Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning , 2009, Science.

[44]  R. Wightman,et al.  PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosine , 2011, Molecular pain.

[45]  Khajak Berberian,et al.  Transparent Electrode Materials for Simultaneous Amperometric Detection of Exocytosis and Fluorescence Microscopy. , 2012, Journal of biomaterials and nanobiotechnology.

[46]  K. Bosse,et al.  Aberrant striatal dopamine transmitter dynamics in brain‐derived neurotrophic factor‐deficient mice , 2012, Journal of neurochemistry.

[47]  John L. Zhou,et al.  Occurrence and removal of endocrine disrupting chemicals in wastewater. , 2008, Chemosphere.

[48]  R. Wightman,et al.  Real-time monitoring of chemical transmission in slices of the murine adrenal gland. , 2010, Endocrinology.

[49]  R. Wightman,et al.  Rapid Dopamine Signaling Differentially Modulates Distinct Microcircuits within the Nucleus Accumbens during Sucrose-Directed Behavior , 2011, The Journal of Neuroscience.

[50]  Hoon-Ki Min,et al.  Evolution of Deep Brain Stimulation: Human Electrometer and Smart Devices Supporting the Next Generation of Therapy , 2009, Neuromodulation : journal of the International Neuromodulation Society.

[51]  Terry Lohrenz,et al.  Sub-Second Dopamine Detection in Human Striatum , 2011, PloS one.

[52]  Greg A. Gerhardt,et al.  Effects of electrical stimulation of brain reward sites on release of dopamine in rat: An in vivo electrochemical study , 1988, Brain Research Bulletin.

[53]  B. J. Venton,et al.  Nafion-CNT coated carbon-fiber microelectrodes for enhanced detection of adenosine. , 2012, The Analyst.

[54]  Lisa J. Mellander,et al.  Estradiol Inhibits Depolarization-Evoked Exocytosis in PC12 Cells via N-Type Voltage-Gated Calcium Channels , 2010, Cellular and Molecular Neurobiology.

[55]  Jay Hirsh,et al.  Journal of Neuroscience Methods Quantitative Evaluation of Serotonin Release and Clearance in Drosophila , 2022 .

[56]  R. Wightman,et al.  Subsecond dopamine release promotes cocaine seeking , 2003, Nature.

[57]  C. Haynes,et al.  Assessment of functional changes in nanoparticle-exposed neuroendocrine cells with amperometry: exploring the generalizability of nanoparticle-vesicle matrix interactions , 2010, Analytical and bioanalytical chemistry.

[58]  A. Ewing,et al.  Carbon-ring microelectrode arrays for electrochemical imaging of single cell exocytosis: fabrication and characterization. , 2012, Analytical chemistry.

[59]  C. Amatore,et al.  Prediction of local pH variations during amperometric monitoring of vesicular exocytotic events at chromaffin cells. , 2010, Chemphyschem : a European journal of chemical physics and physical chemistry.

[60]  Lisa J. Mellander,et al.  Temporal resolution in electrochemical imaging on single PC12 cells using amperometry and voltammetry at microelectrode arrays. , 2011, Analytical chemistry.

[61]  J. Hensler,et al.  Density and function of central serotonin (5‐HT) transporters, 5‐HT1A and 5‐HT2A receptors, and effects of their targeting on BTBR T+tf/J mouse social behavior , 2011, Journal of neurochemistry.

[62]  R. Wightman,et al.  Characterization of local pH changes in brain using fast-scan cyclic voltammetry with carbon microelectrodes. , 2010, Analytical chemistry.

[63]  R. Wightman,et al.  Phasic Nucleus Accumbens Dopamine Encodes Risk-Based Decision-Making Behavior , 2012, Biological Psychiatry.

[64]  C. Lansink,et al.  Role for mTOR Signaling and Neuronal Activity in Morphine-Induced Adaptations in Ventral Tegmental Area Dopamine Neurons , 2011, Neuron.

[65]  Young-Min Shon,et al.  High frequency stimulation of the subthalamic nucleus evokes striatal dopamine release in a large animal model of human DBS neurosurgery. , 2010 .

[66]  Andrew G Ewing,et al.  Development and characterization of a voltammetric carbon-fiber microelectrode pH sensor. , 2010, Langmuir : the ACS journal of surfaces and colloids.