Genetic Screening for Signal Transduction in the Era of Network Biology

[1]  C. Waddington Canalization of Development and the Inheritance of Acquired Characters , 1942, Nature.

[2]  B. Bainbridge,et al.  Genetics , 1981, Experientia.

[3]  C. Nüsslein-Volhard,et al.  Mutations affecting segment number and polarity in Drosophila , 1980, Nature.

[4]  AC Tose Cell , 1993, Cell.

[5]  P. Lawrence,et al.  Regulation of cell number in Drosopfiila , 1994, Nature.

[6]  E. Wieschaus,et al.  Embryonic transcription and the control of developmental pathways. , 1996, Genetics.

[7]  S. Lindquist,et al.  Hsp90 as a capacitor for morphological evolution , 1998, Nature.

[8]  Norbert Perrimon,et al.  Are There Close Encounters Between Signaling Pathways? , 2000, Science.

[9]  I. Weinstein Addiction to Oncogenes--the Achilles Heal of Cancer , 2002, Science.

[10]  G. Rubin,et al.  Quantitative Analysis of Bristle Number in Drosophila Mutants Identifies Genes Involved in Neural Development , 2003, Current Biology.

[11]  James R. Knight,et al.  A Protein Interaction Map of Drosophila melanogaster , 2003, Science.

[12]  Gary D Bader,et al.  Global Mapping of the Yeast Genetic Interaction Network , 2004, Science.

[13]  A. Barabasi,et al.  Network biology: understanding the cell's functional organization , 2004, Nature Reviews Genetics.

[14]  Lan V. Zhang,et al.  Evidence for dynamically organized modularity in the yeast protein–protein interaction network , 2004, Nature.

[15]  J. Stelling,et al.  Robustness of Cellular Functions , 2004, Cell.

[16]  G. Church,et al.  A global view of pleiotropy and phenotypically derived gene function in yeast , 2005, Molecular systems biology.

[17]  A. Wagner Robustness and Evolvability in Living Systems , 2005 .

[18]  D. Lauffenburger,et al.  A Systems Model of Signaling Identifies a Molecular Basis Set for Cytokine-Induced Apoptosis , 2005, Science.

[19]  Pengyu Hong,et al.  Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays , 2006, Nature Methods.

[20]  C. Wilke,et al.  Robustness and Evolvability in Living Systems , 2006 .

[21]  Adam A. Friedman,et al.  A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling , 2006, Nature.

[22]  E. Ruppin,et al.  Multiple knockout analysis of genetic robustness in the yeast metabolic network , 2006, Nature Genetics.

[23]  A. Fraser,et al.  Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways , 2006, Nature Genetics.

[24]  Sean R. Collins,et al.  Global landscape of protein complexes in the yeast Saccharomyces cerevisiae , 2006, Nature.

[25]  Greg Gibson,et al.  Epidermal Growth Factor Receptor and Transforming Growth Factor-β Signaling Contributes to Variation for Wing Shape in Drosophila melanogaster , 2006, Genetics.

[26]  N. Hao,et al.  Genome-Scale Analysis Reveals Sst2 as the Principal Regulator of Mating Pheromone Signaling in the Yeast Saccharomyces cerevisiae , 2006, Eukaryotic Cell.

[27]  Lawrence Lum,et al.  Prevalence of off-target effects in Drosophila RNA interference screens , 2006, Nature.

[28]  R. Rosenfeld Nature , 2009, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.