Allelic variation in CRHR1 predisposes to panic disorder: evidence for biased fear processing

[1]  G. Alpers,et al.  The functional −1019C/G HTR1A polymorphism and mechanisms of fear , 2014, Translational Psychiatry.

[2]  J. Endicott,et al.  Schedule for Affective Disorders and Schizophrenia , 2014 .

[3]  C. Freitag,et al.  The genetic contribution of the NO system at the glutamatergic post-synapse to schizophrenia: Further evidence and meta-analysis , 2014, European Neuropsychopharmacology.

[4]  M. Kanehisa,et al.  Association between corticotropin-releasing hormone receptor 1 and 2 (CRHR1 and CRHR2) gene polymorphisms and personality traits , 2013, Psychiatric genetics.

[5]  A. Jansen,et al.  Neural substrates of treatment response to cognitive-behavioral therapy in panic disorder with agoraphobia. , 2013, The American journal of psychiatry.

[6]  Vladimir I. Vladimirov,et al.  Association of CRHR1 variants and posttraumatic stress symptoms in hurricane exposed adults. , 2013, Journal of anxiety disorders.

[7]  Pedro G. Ferreira,et al.  Transcriptome and genome sequencing uncovers functional variation in humans , 2013, Nature.

[8]  R. Oosting,et al.  Human Fear Acquisition Deficits in Relation to Genetic Variants of the Corticotropin Releasing Hormone Receptor 1 and the Serotonin Transporter , 2013, PloS one.

[9]  Martin H. Schmidt,et al.  Interactive effects of corticotropin-releasing hormone receptor 1 gene and childhood adversity on depressive symptoms in young adults: Findings from a longitudinal study , 2013, European Neuropsychopharmacology.

[10]  A. Jansen,et al.  Altered top-down and bottom-up processing of fear conditioning in panic disorder with agoraphobia , 2013, Psychological Medicine.

[11]  Wanhong Liu,et al.  Negative life events and corticotropin-releasing-hormone receptor1 gene in recurrent major depressive disorder , 2013, Scientific Reports.

[12]  A. Gloster,et al.  Effect of Cognitive-Behavioral Therapy on Neural Correlates of Fear Conditioning in Panic Disorder , 2013, Biological Psychiatry.

[13]  G. Alpers,et al.  Meta‐analysis argues for a female‐specific role of MAOA‐uVNTR in panic disorder in four European populations , 2012, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[14]  A. Gloster,et al.  Dynamics of Defensive Reactivity in Patients with Panic Disorder and Agoraphobia: Implications for the Etiology of Panic Disorder , 2012, Biological Psychiatry.

[15]  F. Holsboer,et al.  Early‐life stress‐induced anxiety‐related behavior in adult mice partially requires forebrain corticotropin‐releasing hormone receptor 1 , 2012, The European journal of neuroscience.

[16]  S. Langenecker,et al.  Variation in the Corticotropin-Releasing Hormone Receptor 1 (CRHR1) Gene Influences fMRI Signal Responses during Emotional Stimulus Processing , 2012, The Journal of Neuroscience.

[17]  F. Holsboer,et al.  Consolidation of Remote Fear Memories Involves Corticotropin-Releasing Hormone (CRH) Receptor Type 1-Mediated Enhancement of AMPA Receptor GluR1 Signaling in the Dentate Gyrus , 2012, Neuropsychopharmacology.

[18]  David L. Walker,et al.  EFFECTS OF CONTINUOUSLY ENHANCED CORTICOTROPIN RELEASING FACTOR EXPRESSION WITHIN THE BED NUCLEUS OF THE STRIA TERMINALIS ON CONDITIONED AND UNCONDITIONED ANXIETY , 2012, Molecular Psychiatry.

[19]  L. Farrer,et al.  A CRHR1 haplotype moderates the effect of adverse childhood experiences on lifetime risk of major depressive episode in African‐American women , 2011, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[20]  E. V. van Rossum,et al.  Glucocorticoid Sensitivity in Mood Disorders , 2011, Neuroendocrinology.

[21]  M. Bradley,et al.  Aversive Imagery in Panic Disorder: Agoraphobia Severity, Comorbidity, and Defensive Physiology , 2011, Biological Psychiatry.

[22]  A. Gloster,et al.  Neuropeptide S receptor gene — converging evidence for a role in panic disorder , 2011, Molecular Psychiatry.

[23]  D. Cicchetti,et al.  Moderation of the association between childhood maltreatment and neuroticism by the corticotropin-releasing hormone receptor 1 gene. , 2011, Journal of child psychology and psychiatry, and allied disciplines.

[24]  F. Holsboer,et al.  Forebrain CRHR1 deficiency attenuates chronic stress-induced cognitive deficits and dendritic remodeling , 2011, Neurobiology of Disease.

[25]  P. Moorjani,et al.  Corticotrophin-Releasing Hormone Type 1 Receptor Gene (CRHR1) Variants Predict Posttraumatic Stress Disorder Onset and Course in Pediatric Injury Patients , 2011, Disease markers.

[26]  U. John,et al.  Childhood maltreatment, the corticotropin‐releasing hormone receptor gene and adult depression in the general population , 2010, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[27]  A. Thorsell Brain neuropeptide Y and corticotropin-releasing hormone in mediating stress and anxiety , 2010, Experimental biology and medicine.

[28]  Luigi Ferrucci,et al.  Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain , 2010, PLoS genetics.

[29]  A. Jansen,et al.  Neural correlates of aversive conditioning: development of a functional imaging paradigm for the investigation of anxiety disorders , 2010, European Archives of Psychiatry and Clinical Neuroscience.

[30]  Elisabeth B Binder,et al.  Polymorphisms in CRHR1 and the Serotonin Transporter Loci: Gene × Gene × Environment Interactions on Depressive Symptoms , 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[31]  M. Davis,et al.  Selective participation of the bed nucleus of the stria terminalis and CRF in sustained anxiety-like versus phasic fear-like responses , 2009, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[32]  M. Höfler,et al.  Mechanism of action in CBT (MAC): methods of a multi-center randomized controlled trial in 369 patients with panic disorder and agoraphobia , 2009, European Archives of Psychiatry and Clinical Neuroscience.

[33]  F. Holsboer,et al.  CRH Signaling , 2009, Annals of the New York Academy of Sciences.

[34]  A. Caspi,et al.  Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension. , 2009, Archives of general psychiatry.

[35]  B. Bradley,et al.  Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene , 2009, Front. Behav. Neurosci..

[36]  C. Béroud,et al.  Human Splicing Finder: an online bioinformatics tool to predict splicing signals , 2009, Nucleic acids research.

[37]  D. Wasserman,et al.  Depression in suicidal males: genetic risk variants in the CRHR1 gene , 2009, Genes, brain, and behavior.

[38]  M. Weissman,et al.  Association and linkage analysis of candidate genes GRP, GRPR, CRHR1, and TACR1 in panic disorder , 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[39]  W. Maier,et al.  Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder , 2008, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[40]  Philip S Rosenberg,et al.  PGA: power calculator for case-control genetic association analyses , 2008, BMC Genetics.

[41]  Florian Holsboer,et al.  Central CRH system in depression and anxiety--evidence from clinical studies with CRH1 receptor antagonists. , 2008, European journal of pharmacology.

[42]  Michel Georges,et al.  Patrocles: a database of polymorphic miRNA-mediated gene regulation in vertebrates , 2008, Nucleic Acids Res..

[43]  K. Ressler,et al.  Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. , 2008, Archives of general psychiatry.

[44]  D. Stephan,et al.  A survey of genetic human cortical gene expression , 2007, Nature Genetics.

[45]  Zhaohui S. Qin,et al.  A second generation human haplotype map of over 3.1 million SNPs , 2007, Nature.

[46]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[47]  Steven Taylor,et al.  Robust dimensions of anxiety sensitivity: development and initial validation of the Anxiety Sensitivity Index-3. , 2007, Psychological assessment.

[48]  Z. Cao,et al.  Association of corticotropin-releasing hormone receptor1 gene SNP and haplotype with major depression , 2006, Neuroscience Letters.

[49]  J. Schulkin,et al.  A neuroendocrine mechanism for sustaining fear , 2005, Trends in Neurosciences.

[50]  Thomas Werner,et al.  MatInspector and beyond: promoter analysis based on transcription factor binding sites , 2005, Bioinform..

[51]  Olga V. Demler,et al.  Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. , 2005, Archives of general psychiatry.

[52]  Mark Daly,et al.  Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..

[53]  K. Catt,et al.  Corticotropin releasing hormone receptors: two decades later , 2004, Peptides.

[54]  F. Holsboer,et al.  Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress , 2003, Nature Neuroscience.

[55]  A. Moorman,et al.  Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data , 2003, Neuroscience Letters.

[56]  F. Speleman,et al.  Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes , 2002, Genome Biology.

[57]  F. Holsboer,et al.  Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1 , 1998, Nature Genetics.

[58]  A. Farmer,et al.  The Composite International Diagnostic Interview. An epidemiologic Instrument suitable for use in conjunction with different diagnostic systems and in different cultures. , 1988, Archives of general psychiatry.

[59]  A. Hamm,et al.  When the threat comes from inside the body: a neuroscience based learning perspective of the etiology of panic disorder. , 2014, Restorative neurology and neuroscience.

[60]  石飛 佳宣 Association of CRHR1 and CRHR2 with major depressive disorder and panic disorder in a Japanese population , 2013 .

[61]  C. Grillon,et al.  Overgeneralization of conditioned fear as a pathogenic marker of panic disorder. , 2010, The American journal of psychiatry.

[62]  C. Grillon,et al.  Phasic vs Sustained Fear in Rats and Humans: Role of the Extended Amygdala in Fear vs Anxiety , 2010, Neuropsychopharmacology.

[63]  Florian Holsboer,et al.  Stress hormone regulation: biological role and translation into therapy. , 2010, Annual review of psychology.

[64]  D. Swaab,et al.  Corticotropin-releasing hormone and arginine vasopressin in depression focus on the human postmortem hypothalamus. , 2010, Vitamins and hormones.

[65]  D. Sheehan,et al.  The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. , 1998, The Journal of clinical psychiatry.

[66]  S. Reiss,et al.  Anxiety sensitivity, anxiety frequency and the prediction of fearfulness. , 1986, Behaviour research and therapy.

[67]  D. Klein,et al.  Schedule for Affective Disorders and Schizophrenia--Lifetime Version modified for the study of anxiety disorders (SADS-LA): rationale and conceptual development. , 1986, Journal of psychiatric research.

[68]  D. Chambless,et al.  Assessment of fear of fear in agoraphobics: the body sensations questionnaire and the agoraphobic cognitions questionnaire. , 1984, Journal of consulting and clinical psychology.