Metabolism of methylglyoxal in microorganisms.

INTRODUCTION 49 A METHYl.GLYOXAL BYPASS OF THE EMBDEN·MEYERHOF PATHWAy...... 51 CYTOTOXIC NATURE OF METHYLGLYOXAL ........ 54 ENZYMA TJ[C FORMATION OF METHYLGLYOXAL 54 Studies on Methylglyoxal Synthase 54 Glyceraldehyde 3.Phosphate and Glyceraldehyde as Possible Precursors of Methylglyoxal 57 Acetol Dehydrogenase 57 Methylglyoxal from Aminoacetone 58 REACTIONS FOR THE UTILIZATION OF METHYLGLYOXAL 58 The Glyoxalase System 58 Methylg,yoxal Dehydrogen ase 60 Formaldehyde Dehydrogenase 60