Targeting Tumor-Associated Fibroblasts for Therapeutic Delivery in Desmoplastic Tumors.
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William Y. Kim | Yuhua Wang | Leaf Huang | Lei Miao | Qi Liu | Shihao Hu | C. M. Lin | Weiyan Yin | Cong Luo | Lina Liu | Cong Luo | Cong Luo
[1] J. DeSimone,et al. Subtumoral analysis of PRINT nanoparticle distribution reveals targeting variation based on cellular and particle properties. , 2016, Nanomedicine : nanotechnology, biology, and medicine.
[2] W. Quax,et al. Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity , 2016, Oncogene.
[3] M. Detmar,et al. Findings questioning the involvement of Sigma-1 receptor in the uptake of anisamide-decorated particles. , 2016, Journal of controlled release : official journal of the Controlled Release Society.
[4] Leaf Huang,et al. Stromal barriers and strategies for the delivery of nanomedicine to desmoplastic tumors. , 2015, Journal of controlled release : official journal of the Controlled Release Society.
[5] R. Jain,et al. Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages , 2015, PloS one.
[6] William Y. Kim,et al. Nanoparticle modulation of the tumor microenvironment enhances therapeutic efficacy of cisplatin. , 2015, Journal of controlled release : official journal of the Controlled Release Society.
[7] Ralph Weissleder,et al. Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug , 2015, Nature Communications.
[8] Jen Jen Yeh,et al. Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma , 2015, Nature Genetics.
[9] O. De Wever,et al. Cancer-associated fibroblasts as target and tool in cancer therapeutics and diagnostics , 2015, Virchows Archiv.
[10] D. Hedley,et al. Targeting of metastasis-promoting tumor-associated fibroblasts and modulation of pancreatic tumor-associated stroma with a carboxymethylcellulose-docetaxel nanoparticle. , 2015, Journal of controlled release : official journal of the Controlled Release Society.
[11] David M. Kaetzel,et al. Metastasis suppressor NME1 regulates melanoma cell morphology, self‐adhesion and motility via induction of fibronectin expression , 2015, Experimental dermatology.
[12] William Y. Kim,et al. Nanoparticles with Precise Ratiometric Co‐Loading and Co‐Delivery of Gemcitabine Monophosphate and Cisplatin for Treatment of Bladder Cancer , 2014, Advanced functional materials.
[13] G. Wahl,et al. Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy , 2014, Cell.
[14] Yuan Zhang,et al. Synergistic anti-tumor effects of combined gemcitabine and cisplatin nanoparticles in a stroma-rich bladder carcinoma model. , 2014, Journal of controlled release : official journal of the Controlled Release Society.
[15] Lin Mei,et al. The effect of autophagy inhibitors on drug delivery using biodegradable polymer nanoparticles in cancer treatment. , 2014, Biomaterials.
[16] W. Mesker,et al. Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts , 2014, Oncogene.
[17] H. Yeger,et al. TGF-β1 induces EMT reprogramming of porcine bladder urothelial cells into collagen producing fibroblasts-like cells in a Smad2/Smad3-dependent manner , 2013, Journal of Cell Communication and Signaling.
[18] Huan Meng,et al. Two-wave nanotherapy to target the stroma and optimize gemcitabine delivery to a human pancreatic cancer model in mice. , 2013, ACS nano.
[19] Yuhua Wang,et al. Lipid-coated Cisplatin nanoparticles induce neighboring effect and exhibit enhanced anticancer efficacy. , 2013, ACS nano.
[20] Lu Zhang,et al. Intravenous delivery of siRNA targeting CD47 effectively inhibits melanoma tumor growth and lung metastasis. , 2013, Molecular therapy : the journal of the American Society of Gene Therapy.
[21] R. Swann,et al. Tumor Stromal Architecture Can Define the Intrinsic Tumor Response to VEGF-Targeted Therapy , 2013, Clinical Cancer Research.
[22] I. Endo,et al. Conditionally replicative adenoviral vectors for imaging the effect of chemotherapy on pancreatic cancer cells , 2013, Cancer science.
[23] Shyh-Dar Li,et al. Docetaxel conjugate nanoparticles that target α-smooth muscle actin-expressing stromal cells suppress breast cancer metastasis. , 2013, Cancer research.
[24] C. Lewis,et al. Macrophage regulation of tumor responses to anticancer therapies. , 2013, Cancer cell.
[25] Y. Ba,et al. Transforming growth factor-1 promotes the transcriptional activation of plasminogen activator inhibitor type 1 in carcinoma-associated fibroblasts. , 2012, Molecular medicine reports.
[26] J. Bussink,et al. Targeting Hypoxia, HIF-1, and Tumor Glucose Metabolism to Improve Radiotherapy Efficacy , 2012, Clinical Cancer Research.
[27] T. Golub,et al. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion , 2012, Nature.
[28] R. Jain,et al. Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner , 2012, Nature nanotechnology.
[29] Z. Werb,et al. The extracellular matrix: A dynamic niche in cancer progression , 2012, The Journal of cell biology.
[30] M. Uesaka,et al. Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. , 2011, Nature nanotechnology.
[31] P. Cirri,et al. Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression , 2011, Cancer and Metastasis Reviews.
[32] Rakesh K. Jain,et al. Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases , 2011, Nature Reviews Drug Discovery.
[33] William C Hines,et al. Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression , 2011, Nature Medicine.
[34] S. Denmeade,et al. Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin , 2009, Molecular Cancer Therapeutics.
[35] Xia Zhang,et al. The expression of exogenous genes in macrophages: obstacles and opportunities. , 2009, Methods in molecular biology.
[36] Y. Sung,et al. Gene therapy using TRAIL-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial glioma. , 2008, Cancer research.
[37] R. Weissleder,et al. Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide , 2008, Molecular Cancer Therapeutics.
[38] Leaf Huang,et al. An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor. , 2008, Journal of controlled release : official journal of the Controlled Release Society.
[39] G. Giaccone,et al. TRAIL therapy in non–small cell lung cancer cells: sensitization to death receptor–mediated apoptosis by proteasome inhibitor bortezomib , 2007, Molecular Cancer Therapeutics.
[40] Kazunori Kataoka,et al. Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-β signaling , 2007, Proceedings of the National Academy of Sciences.
[41] A. Albini,et al. TRAIL inhibits angiogenesis stimulated by VEGF expression in human glioblastoma cells , 2006, British Journal of Cancer.
[42] Won-Kyung Cho,et al. Adeno‐associated virus‐mediated gene transfer of a secreted form of TRAIL inhibits tumor growth and occurrence in an experimental tumor model , 2006, The journal of gene medicine.
[43] R. Jain. Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy , 2005, Science.
[44] Jacques Buffle,et al. Size effects on diffusion processes within agarose gels. , 2004, Biophysical journal.
[45] R. Weissleder,et al. Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy. , 2004, Cancer research.
[46] D. Lauffenburger,et al. Self-organization of polarized cell signaling via autocrine circuits: computational model analysis. , 2004, Biophysical journal.
[47] H. Kalthoff,et al. FAP-1 in pancreatic cancer cells: functional and mechanistic studies on its inhibitory role in CD95-mediated apoptosis. , 2001, Journal of cell science.
[48] S. Batra,et al. Combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and actinomycin D induces apoptosis even in TRAIL-resistant human pancreatic cancer cells. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.
[49] R K Jain,et al. Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: clinical implications. , 1999, Cancer research.
[50] K. Heider,et al. Polycation‐based DNA complexes for tumor‐targeted gene delivery in vivo , 1999, The journal of gene medicine.