Application of chest high‐resolution computer tomography in young children with cystic fibrosis

Summary. High‐resolution computed tomography (HRCT) of the chest permits early detection of lung disease; two relevant scoring systems (Bhalla and Nathanson) have been developed to describe CF lung disease. Comparisons between the two scoring systems have not been made, and it is not known which system is more appropriate for young children, i.e., the age group where other objective markers are scarce. We reviewed the clinical findings, pulmonary function data, and HRCT of 16 children aged less than 12 years.

[1]  Christina J. Herold,et al.  Cystic fibrosis: CT assessment of lung involvement in children and adults. , 1999, Radiology.

[2]  Chest radiology in cystic fibrosis: is scoring useful? , 1994, Thorax.

[3]  J. Carlin,et al.  Critical evaluation of three chest radiograph scores in cystic fibrosis. , 1994, Thorax.

[4]  High resolution computed tomography in Cystic Fibrosis: Correlation with pulmonary function and assessment of prognostic value , 1996, Irish journal of medical science.

[5]  R. Stiglbauer,et al.  High Resolution CT in Children with Cystic Fibrosis , 1992, Acta radiologica.

[6]  M. Hodson,et al.  High resolution computed tomography in adult cystic fibrosis patients with mild lung disease. , 1991, Clinical radiology.

[7]  Maya Ramagopal,et al.  High-resolution computed tomography of the chest in children with cystic fibrosis: support for use as an outcome surrogate , 1999, Pediatric Radiology.

[8]  D. Lynch,et al.  Pediatric pulmonary disease: assessment with high-resolution ultrafast CT. , 1990, Radiology.

[9]  K. Conboy,et al.  Ultrafast computerized tomography of the chest in cystic fibrosis: A new scoring system , 1991, Pediatric pulmonology.

[10]  Melvin Berger,et al.  Current understanding of the inflammatory process in cystic fibrosis: Onset and etiology , 1997, Pediatric pulmonology.

[11]  Kuhn Jp.  High-resolution computed tomography of pediatric pulmonary parenchymal disorders. , 1993 .

[12]  A. Friedman,et al.  High-resolution CT in the acute exacerbation of cystic fibrosis: evaluation of acute findings, reversibility of those findings, and clinical correlation. , 1997, AJR. American journal of roentgenology.

[13]  D. McCauley,et al.  Cystic fibrosis: scoring system with thin-section CT. , 1991, Radiology.

[14]  D. Hansell,et al.  High-resolution computed tomography in pulmonary cystic fibrosis. , 1989, The British journal of radiology.

[15]  A. Brody.  Cystic fibrosis: when should high-resolution computed tomography of the chest be obtained? , 1998, Pediatrics.

[16]  M. Candusso,et al.  Cystic Fibrosis in Children: HRCT Findings and Distribution of Disease , 1996, Journal of thoracic imaging.

[17]  T. Boat,et al.  Outcome measures for clinical trials in cystic fibrosis. Summary of a Cystic Fibrosis Foundation consensus conference. , 1994, The Journal of pediatrics.

[18]  D. Riches,et al.  Early pulmonary inflammation in infants with cystic fibrosis. , 1995, American journal of respiratory and critical care medicine.