Subtypes of HBsAg in Eastern and South‐Eastern Europe

Abstract. A total of 481 serum samples was collected from asymptomatic carriers of H B,Ag as well as some patients with acute and chronic hepatitis, type B. The sera were obtained mainly from blood banks in the following countries: Poland, Hungary, Romania, Bulgaria, Yugoslavia, and the European part of the Soviet Union. Asymptomatic carriers of HBsAg from Poland and Hungary showed a preponderance of adw subtype over uyw subtype (Poland ‐80.7% adw, Hungary ‐72.2% adw). Carriers from the remaining countries showed the reverse situation: Bulgaria ‐71.5% ayw, Yugoslavia ‐79.0% ayw, Romania ‐82.8% ayw, Soviet Union ‐87.5% ayw. No individuals were found among these indigenous populations to have the adr or ayr subtypes but two carriers appeared to have the unusual subtype adyw.

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