Proposed reference sequences for hepatitis E virus subtypes.

The nomenclature of hepatitis E virus (HEV) subtypes is inconsistent and makes comparison of different studies problematic. We have provided a table of proposed complete genome reference sequences for each subtype. The criteria for subtype assignment vary between different genotypes and methodologies, and so a conservative pragmatic approach has been favoured. Updates to this table will be posted on the International Committee on Taxonomy of Viruses website (http://talk.ictvonline.org/r.ashx?C). The use of common reference sequences will facilitate communication between researchers and help clarify the epidemiology of this important human pathogen. This subtyping procedure might be adopted for other taxa of the genus Orthohepevirus.

[1]  E. Thiry,et al.  Belgian Wildlife as Potential Zoonotic Reservoir of Hepatitis E Virus , 2017, Transboundary and emerging diseases.

[2]  G. Lee,et al.  Chronic Infection With Camelid Hepatitis E Virus in a Liver Transplant Recipient Who Regularly Consumes Camel Meat and Milk. , 2016, Gastroenterology.

[3]  L. Rostaing,et al.  Temporal evolution of the distribution of hepatitis E virus genotypes in Southwestern France. , 2015, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

[4]  P. Simmonds,et al.  Variability and pathogenicity of hepatitis E virus genotype 3 variants , 2015, The Journal of general virology.

[5]  M. Groschup,et al.  Hepatitis E Virus Genotype 3 Diversity: Phylogenetic Analysis and Presence of Subtype 3b in Wild Boar in Europe , 2015, Viruses.

[6]  I. Ushiro-Lumb,et al.  Hepatitis E virus in blood components: a prevalence and transmission study in southeast England , 2014, The Lancet.

[7]  P. Simmonds,et al.  Consensus proposals for classification of the family Hepeviridae , 2014, The Journal of general virology.

[8]  R. Tedder,et al.  Indigenous hepatitis E in England and wales from 2003 to 2012: evidence of an emerging novel phylotype of viruses. , 2014, The Journal of infectious diseases.

[9]  Koichiro Tamura,et al.  MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. , 2013, Molecular biology and evolution.

[10]  E. F. Oliveira-Filho,et al.  Genetic variability of HEV isolates: inconsistencies of current classification. , 2013, Veterinary microbiology.

[11]  P. Simmonds,et al.  Genetic Variability and the Classification of Hepatitis E Virus , 2013, Journal of Virology.

[12]  J. Izopet,et al.  Hepatitis E Virus Strains in Rabbits and Evidence of a Closely Related Strain in Humans, France , 2012, Emerging infectious diseases.

[13]  P. Liu,et al.  Phylogenetic analysis of 626 hepatitis E virus (HEV) isolates from humans and animals in China (1986-2011) showing genotype diversity and zoonotic transmission. , 2012, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

[14]  P. Simmonds.  SSE: a nucleotide and amino acid sequence analysis platform , 2012, BMC Research Notes.

[15]  G. Metreveli,et al.  Molecular epidemiology of hepatitis E virus in humans, pigs and wild boars in Sweden , 2010, Epidemiology and Infection.

[16]  C. Hagedorn,et al.  Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis , 2006, Reviews in medical virology.